Thomas A Steitz PhD

Sterling Professor of Molecular Biophysics and Biochemistry and Professor of Chemistry; Investigator, Howard Hughes Medical Institute

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology

Office of Student ResearchInfectious DiseasesTuberculosisStructural BiologyCenter for RNA Science and Medicine, YaleMolecular Biophysics and Biochemistry: Cell Cycle and Transcriptional Regulation; DNA Replication and Repair; RNA Biology; Structural Biology; Thomas Steitz Lab

Research Interests

Protein Structure; Proteins and Macromolecules; Protein Nucleic Acid Complexes; X-ray Crystallography more...


  • BA, Lawrence College, 1962
  • Ph.D., Harvard University, 1966

Selected Publications

  • Bailey, S., Wing, R.A., and Steitz, T.A. (2006). The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Cell 126:893-904.
  • Schmeing, T.M., Huang, K.S., Strobel, S.A., and Steitz, T.A. (2005). An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature 438:520-524.
  • Blaha G, Stanley RE, Steitz TA. Science. 2009 Aug 21;325(5943):966-70



Latest News


Edit Profile