Shangqin Guo PhD

Assistant Professor of Cell Biology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development

Office of Student ResearchStem Cell Center, Yale: Transcriptional Regulation of Stem and Progenitor Cells; Stem Cell Niche and Homing; Stem Cell Self-Renewal and Cell Symmetry; Tissue Specific Stem CellsCell Biology

Research Interests

Cell fate control; Reprogramming; Hematopoietic stem and progenitors; Leukemogenesis; Cell cycle; live-cell imaging more...


  • Ph.D., Boston University, 2005

Selected Publications

  • Non-stochastic reprogramming from a privileged somatic cell state. Shangqin Guo (corresponding author), Xiaoyuan Zi, Vincent P. Schulz, Jijun Cheng, Mei Zhong, Sebastian H.J. Koochaki, Cynthia M. Megyola, Xinghua Pan, Kartoosh Heydari, Sherman M. Weissman, Patrick G. Gallagher, Diane S. Krause, Rong Fan and Jun Lu. Cell, online Jan 30th, 2014
  • An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis. Cheng J, Guo S (co-first and co-corresponding author), Chen S, Mastriano SJ, Liu C, D'Alessio AC, Hysolli E, Guo Y, Yao H, Megyola CM, Li D, Liu J, Pan W, Roden CA, Zhou XL, Heydari K, Chen J, Park IH, Ding Y, Zhang Y, Lu J. Cell Rep. 2013 Oct 31;5(2):471-81.
  • Dynamic migration and cell-cell interactions of early reprogramming revealed by high-resolution time-lapse imaging. Megyola CM, Gao Y, Teixeira AM, Cheng J, Heydari K, Cheng EC, Nottoli T, Krause DS, Lu J, Guo S. Stem Cells. 2013 May;31(5):895-905.



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