The lab of Lawrence Rizzolo, Ph.D., is inviting applications to work on a project that involves tissue engineering and stem cell transplantation to study retinal diseases such as Age Related Macular Degeneration (AMD). AMD is the leading cause of visual impairment in the US. The macula is the region of the retina that is responsible for visual acuity. We have adapted current methods for culturing the retinal pigment epithelium (RPE) and retinal progenitor cells to a novel method for co-culture in a 3D configuration that emulates the outer retina. Current projects use this engineered tissue 1) to study agents that promote differentiation and their mechanism of action and 2) to determine whether the engineered tissue will integrate functionally into the host retina of animals with retinal injury or degeneration.
Essential Qualifications: The successful candidate must have a doctoral degree in cell biology or a related field. Experience in standard tissue culture and animal surgery is required. Excellent oral and written communication skills and the ability to work independently or in collaboration are needed. Willingness to learn new techniques is essential.
Preferred Qualifications: Experience in stem cell biology, RNAi, immunobiochemisty, immunocytochemistry, quantitative, real time RT-PCR are desirable.
Interested candidates should submit their CV including names and contact information for three references and a short description of their doctoral training and future research goals.
Lawrence Rizzolo, Ph.D.
Department of Surgery
PO Box 208062
New Haven, CT 06520-8062