Human Embryonic/Induced Pluripotent Stem Cell Core
Mission
The mission of the Yale Stem Cell Center’s hESC/iPSC Core – now part of the Yale Medical School’s Central Research Cores - is to provide essential services for research on human embryonic stem cells (hESCs) and human induced pluripotent stem cells (iPSCs) to researchers at Yale University and beyond.
- Serves as a central repository and distribution center for hESC and iPSC lines.
- Provides training in thawing, maintenance, expansion, differentiation, and cryopreservation of hESCs/iPSCs.
- Provides service on reprogramming somatic cells into iPSCs.
- Provides service on genome editing on hESCs and iPSCs lines using CRISPR/Cas9 technology including single nucleotide replacement and adding and knocking out of genes.
- Provides service on banking customer’s iPSC lines.
- Orders bulk essential reagents for research on hESCs and iPSCs and distributes to researchers with at discounted prices.
- Provide service on karyotyping and teratoma formation to ensure hESC and iPSC genome stability and pluripotency.
- Opens laboratory to researchers to initiate their hESC/iPSC research.
- Serves as a liaison with the ESCRO committee and assists with and oversees Materials Transfer Agreements for hESC lines as needed.
- Expands all services to external users, including non-profit and biotech companies.
Staff
Technical Director: Caihong Qiu, PhD
Telephone: 203-737-7925
Research Associate: Jason Thomson, BS
Research Associate: Yinghong Ma, PhD
Telephone: (203) 785-6673