David J. Leffell MD
David P. Smith Professor of Dermatology and Professor of Surgery (Otolaryngology and Plastic); Deputy Dean for Clinical Affairs, Yale School of Medicine; Section Chief, Dermatologic Surgery and Cutaneous Oncology

Departments & Organizations
Yale Medical GroupCancer Center, Yale: Head and Neck Cancer Surgery Program | Melanoma Program
YMG Administration
Dermatology: Dermatologic Surgery: Mohs Surgery | Skin Diseases Research Center, Yale
Surgery
Cancer Genetics
Biography
A graduate of Yale College and the McGill University Faculty of Medicine in Montreal, Leffell completed his residency training in internal medicine at Cornell Cooperating Hospitals and then in dermatology at Yale-New Haven Hospital. He did a clinical research fellowship in dermatology at Yale followed by a clinical fellowship in dermatologic surgery at the University of Michigan Medical School in Ann Arbor. Author of the popular book "Total Skin," Leffell is an expert clinician, specializing in skin cancer diagnosis and surgical treatment using the Mohs micrographic technique. The Cutaneous Oncology Unit that he founded in 1988 now performs specialized surgical treatment on more than 3,500 patients annually. His major clinical interest is the management of skin cancer, including basal cell cancer, squamous cell cancer and melanoma. In 1996 Leffell was a member of the research group that discovered the skin cancer gene known as PTCH. In addition, he has conducted collaborative research clarifying the role of ultraviolet radiation in skin cancer and skin aging. Author of more than 100 publications, Leffell has also done research on epidemiologic aspects of skin cancer and wound healing.Education
- B.S., Yale College , 1977
- M.D., McGill University , 1981
Selected Publication
- Asplund A, Gustafsson AC, Wikonkal NM, Sela A, Leffell DJ, Kidd K, Lundeberg J. Brash DE, Ponten F: PTCH codon 1315 polymorphism and risk for nonmelanoma skin cancer, British Journal of Medicine, 152(5):868-73, 2005
Latest Honor and Recognition
- Best Doctors in New York(2009) , Castle and Connolly
Articles
Summer 2000
Total Skin: The Definitive Guide to Whole Skin Care for Life
by David J. Leffell, M.D., professor of dermatology and surgery, Hyperion Books (N.Y.), 2000.
Autumn 2012
Manual of Skin Surgery: A Practical Guide to Dermatologic Procedures, 2nd ed
by David J. Leffell, M.D., HS ’86, FW ’87, the David P. Smith Professor of Dermatology and professor of surgery...
Autumn 2008
62 YMG members in top docs list
New York Magazine’s 2008 list of the region’s top physicians includes 62 physicians from Yale Medical Group (YMG)....
Spring 2001
What's in a name?
Physicians at medical schools around the country usually provide their services through umbrella faculty practice...
Summer 2000
Faculty Practice elects governors
The Yale Faculty Practice, the multi-specialty academic medical practice composed of over 650 School of Medicine...

Summer 2005
As deputy dean, Leffell moves practice into 21st century
With his appointment as deputy dean for clinical affairs in February, David J. Leffell, M.D., HS ’86, continues a task...
Spring 1999
Rimar appointed medical director of Yale Faculty Practice
Stephen Rimar, M.D., HS ’83-87, vice chair for finance and administration in the Department of Anesthesiology, has been...
Winter 1999
Perfecting the Faculty Practice
David J. Leffell, M.D., medical director of the Yale Faculty Practice for the past three years and a professor of...
Spring 2001
New chairs appointed in three departments; clinical leadership changes
Dean David A. Kessler, M.D., has announced the appointment of three new chairs to lead the departments of Cell Biology,...
Spring 2009
Michael J. Caplan, M.D. ’87, Ph.D. ’87, FW ’89, Mark Hochstrasser, Ph.D., David J. Leffell, M.D., David A. McCormick, Ph.D., Scott A. Strobel, Ph.D.
Several faculty members have been named to endowed chairs in recent months. Michael J. Caplan, M.D. ’87, Ph.D. ’87, FW...

Winter 2013
Yale’s Epic challenge
In early October, Gary E. Friedlaender, M.D., a specialist in musculoskeletal oncology who chairs the Department of...

Fall/Winter 2004
Recreating the residency
Under new rules, residents may not work more than 80 hours a week. This change has forced physicians to rethink the...
Spring 1999
Patients, doctors and the bottom line
Market forces and a changing world of medicine have prompted Yale’s 650-member physician organization to take a closer...

Autumn 2005
A year at the helm
Since he arrived at Yale in 2004, Dean Robert Alpern has led faculty to a new vision of the medical school, with a...



