John P Geibel DSc, MD, MSc

Professor of Surgery (Gastrointestinal) and of Cellular and Molecular Physiology; Vice Chair, Surgery; Director, Surgical Research


Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Signal Transduction

Cellular & Molecular Physiology: Physiology and Integrative Medical Biology Track | Graduate Program in Cellular and Molecular Physiology

Surgery: Geibel Lab

Signal Transduction

Biography

John Geibel is Vice Chairman of the Department of Surgery at Yale University School of Medicine and Director of Surgical Research and Professor of Cellular and Molecular Physiology. His early research training was in Innsbruck Austria where he worked in the Physiology Department and investigated renal physiology on the isolated perfused tubule model. He holds a Bachelors of Science Degree in Physiology, an MD and DSc degree as well as a Master’s of Science, and a Master’s of Arts Degree. He has also obtained his Dozent in Medicine from the University of Innsbruck. After obtaining his Dozent he went to Yale University first as a visiting fellow and then joined the faculty in both Surgery and Cellular and Molecular Physiology where he rose through the ranks to Professor in both faculties.

Academically, Professor Geibel’s active research interests are on the role of the Calcium Sensing Receptor (CaSR) in gastrointestinal physiology and pathophysiology. In addition, John Geibel has conducted research in fluid and electrolyte transport in the intestine where he was the first to identify that the colonic crypt can both actively secrete and absorb fluid. He has also identified 4 new transport pathways in the stomach that play important roles in acid secretion and may help to explain some of the hypersecretion of acid that occurs in patients. In addition he maintains a research program in the kidney where he was the first to identify a functional role for the H-ATPase in the proximal tubule; he was also the first to demonstrate a role for Angiotensin on the Na/H exchanger and Na/HCO3 and H-ATPase in the proximal tubule. Professor Geibel is the author of over 150 publications and presents his findings both nationally and internationally. He is the holder of 7 patents on the role of the calcium sensing receptor on gastrointestinal models and is currently actively working to begin clinical trials on a method to stop secretory diarrhea in the developing world based on targeting the calcium sensing receptor.


Education

  • M.S., University of New Brunswick , 1981
  • D.Sc., University of Innsbruck , 1983
  • M.D., University of Innsbruck , 1986

Selected Publication

  • Roginiel AC, Kohut DL, Kaur S, Saleh AM, Weber T, Geibel P, Singh H, and Geibel JP. Effect of NSAIDs on Na+/H+ exchanger activity in Rat colonic crypts. American journal of physiology Cell physiology 2013

Latest Honor and Recognition

  • NIDDK NIH Chair Special Emphasis Panel KO-1 award (2005) , ational Institute of Diabetes and Digestive and Kidney Diseases/National Institute of Health
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