John H. Krystal MD

Robert L. McNeil, Jr. Professor of Translational Research and Professor of Neurobiology; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Departments & Organizations

LCME Medical Students Subcommittee

Office of Student Research

DAHRSInterdepartmental Neuroscience ProgramNeurobiologyNIMH Research Training Program in Childhood-onset Neuropsychiatric Disorders | Albert J. Solnit Integrated Training | Diabetes Research Center | Psychiatry: Center for the Translational Neuroscience of Alcoholism; Clinical Neuroscience Research Unit; Obsessive Compulsive Disorder Research Clinic; Adult Psychiatry; VA National Center for PTSD


Dr. Krystal is a leading expert in the areas of alcoholism, schizophrenia, and post-traumatic stress disorder. His work links psychopharmacology, neuroimaging, and molecular genetics to study the neurobiology and to develop novel treatments for these disorders.

He is a member of the Institute of Medicine of the National Academies. He also serves in a variety of advisory and review capacities for NIAAA, NIMH, Wellcome Trust, Brain and Behavior Research Foundation, and the Karolinska Institutet.

He previously served on the National Alcohol Abuse and Alcoholism Advisory Council (NIAAA), the Department of Defense Psychological Health Advisory Committee, the NIMH Board of Scientific Counselors (chair, 2005-2007), American College of Neuropsychopharmacology (president, 2012), and International College of Neuropsychopharmacology (president-elect).

Dr. Krystal also edits the journal, Biological Psychiatry (impact factor: 9.472).


  • B.A., University of Chicago , 1980
  • M.D., Yale University , 1984

Selected Publication

  • Krystal JH, Sanacora G, Duman RS. Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond. Biol Psychiatry. 2013 Jun 15;73(12):1133-41. doi: 10.1016/j.biopsych.2013.03.026. Review. PubMed PMID: 23726151; PubMed Central PMCID: PMC3671489.

Latest Honor and Recognition

  • Kempf Award for Contributions to Schizophrenia Research through Research and Mentorship(06/2005) , American Psychiatric Association
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