Michael Marsland

Images

Visitors entering from Park Street come in through an atrium that includes a player piano and a waterfall.

A detail from a mural in the atrium.

A rooftop garden on the seventh floor, which includes plantings and a stream, is designed as a meditative space for patients.

A waiting room at Smilow lacks a television but features an aquarium with exotic fish. A television, the hospital’s planners believe, sends a message that patients are in for a long wait.

A detail from a mural in the atrium.

The hospital from Park Street.

Operating rooms were designed with all equipment hanging from the ceiling, making it easier for physicians, nurses, and technicians to move around and easier to clean. “What do I have to do to practice here?” ask new surgery recruits.

Benefactor Joel Smilow.

Maria Menocal was the hospital’s first outpatient in October.

Dean Robert Alpern was among the speakers at the hospital’s dedication in October.

Structural biologist Thomas Steitz shared the 2009 Nobel Prize for Chemistry in October for elucidating the structure of the large subunit of the ribosome, which helps translate DNA information into the proteins that make life possible.

On September 14, the day after police found Annie Le’s body hidden inside a wall at 10 Amistad Street, members of the Yale community gathered for a vigil at Cross Campus.

Gary Ginsberg is the co-author of What’s Toxic, What’s Not, an accessible guide to the risks of common household products.

Peter Salovey

H. Kim Bottomly, Ph.D.

Medical students who launched a free clinic in the Fair Haven neighborhood of New Haven received an Ivy Award last spring for their efforts. From left, Maggie Samuels-Kalow, Ryan Hebert, Mallika Mendu, Christopher Janson, Sara Crager and Andrew Simpson received the award from President Richard Levin.

The Daniel L. Malone Engineering Center is one of two new buildings on Yale’s central campus that is devoted to science.

With President Richard Levin at his side, Robert Alpern, left, the 16th dean of the medical school, greeted faculty in the Historical Library in April. Alpern, who served as dean of the University of Texas Southwestern Medical School, started at Yale on June 1.

W. Mark Saltzman, chair of the new biomedical engineering department, and Erin Lavik, an assistant professor, with a sample of a polymer wafer capable of delivering therapeutic agents in the brain after surgery.

Peter Salovey

Neurosurgeon Dennis Spencer believes new imaging technology could permit targeted surgery or drug delivery.

Kelly Brownell

On the day before the Super Tuesday primaries, Hillary Rodham Clinton, a U.S. senator from New York who is seeking the Democratic Party’s presidential nomination, returned to Yale to lead a discussion of health care issues.

(Shrikant Mane (left), director of the Yale Center for Genome Analysis (YCGA) and Kira Fitzsimons, biotechnology assistant, discuss data produced by the YCGA’s latest gene sequencers, which can sequence the equivalent of more than 300 complete human genomes per month.

October 8: Leaders of Yale and University College London (UCL) and their associated hospitals were joined by former British Prime Minister Tony Blair (right) to sign an agreement creating the YALE–UCL COLLABORATIVE ON BIOMEDICINE, a new partnership in biomedical research and clinical care. (From left) David Fish, M.D., professor of epilepsy and clinical neurophysiology at UCL and managing director, UCL Partners; Malcolm Grant, CBE, L.L.D., president and provost of UCL; Yale President Richard C. Levin; and Yale-New Haven Hospital CEO Marna P. Borgstrom, M.P.H. Blair, founder of the Tony Blair Faith Foundation, is teaching a “Faith and Globalization” seminar at Yale for the second year.

In September, students, faculty, and staff gathered on Yale’s Cross Campus for a candlelight vigil in memory of pharmacology graduate student Annie Le, whose murder in a medical school research building shook the Yale community and the nation.

April 28: The 30th annual SETON ELM AND IVY AWARDS were given in the President’s Room at Yale’s Woolsey Hall. The awards, which honor people and organizations that further partnership between New Haven and Yale, were established with the support of Fenmore Seton, a 1938 Yale College alumnus, and his wife Phyllis, who created an endowment at the Community Foundation for Greater New Haven in 1979. Elm Awards are given to members of the New Haven community, and Ivy Awards are given to Yale staff, faculty, and students. Erin Lavik, Sc.D., associate professor of biomedical engineering and co-organizer of Science Saturdays, a series of weekend presentations by Yale scientists that bring the excitement and passion of research to “kids of all ages” in New Haven.

April 28: The 30th annual SETON ELM AND IVY AWARDS were given in the President’s Room at Yale’s Woolsey Hall. The awards, which honor people and organizations that further partnership between New Haven and Yale, were established with the support of Fenmore Seton, a 1938 Yale College alumnus, and his wife Phyllis, who created an endowment at the Community Foundation for Greater New Haven in 1979. Elm Awards are given to members of the New Haven community, and Ivy Awards are given to Yale staff, faculty, and students. Michael Ma and Sachin Shah of the School of Medicine’s Class of 2011, organizers of this year’s Yale Health Professional Schools Annual Hunger and Homelessness Auction, which raised $32,000 for New Haven-area charities in 2008.

April 28: The 30th annual SETON ELM AND IVY AWARDS were given in the President’s Room at Yale’s Woolsey Hall. The awards, which honor people and organizations that further partnership between New Haven and Yale, were established with the support of Fenmore Seton, a 1938 Yale College alumnus, and his wife Phyllis, who created an endowment at the Community Foundation for Greater New Haven in 1979. Elm Awards are given to members of the New Haven community, and Ivy Awards are given to Yale staff, faculty, and students. New Haven Mayor John DeStefano Jr. (left) and Bruce Alexander (right), vice president for New Haven and State Affairs and Campus Development at Yale, present an Ivy Award to Forrester A. Lee, M.D. Lee, assistant dean for multicultural affairs and professor of medicine at the School of Medicine, is a leader in the Hill Regional Career High School partnerships with Yale and in local celebrations of African-American history.

June 15: Yale University’s Maurice R. Greenberg International Conference Center was the setting for STRATEGIC PROBLEM SOLVING IN GLOBAL HEALTH, the first annual conference of the Global Health Leadership Institute (GHLI). The GHLI, a collaborative effort between the Yale School of Public Health and the Whitney and Betty MacMillan Center for International and Area Studies at Yale, works with leaders in numerous countries to improve the performance of health systems. Elizabeth H. Bradley (kneeling, third from left), Ph.D., founder of the GHLI and professor at the School of Public Health, invited representatives from six countries that have made exceptional improvements in health systems in recent years despite resource obstacles—Ethiopia, Ghana, Liberia, Mexico, Rwanda, and Singapore—to attend the conference.

Psychology major Emily Yudofsky is conducting research aimed at enhancing the effectiveness of public-service advertisements that promote healthy behaviors.

New Haven’s City Chief Administrator, Robert Smuts (right), presents Curtis Patton (center) with a 2008 Ivy Award, joined by Yale President Richard Levin (left).

Many of the speakers at the Bicentennial Symposium joined President Richard Levin, Dean Robert Alpern, and other medical school faculty for a dinner on April 28. Front row, from left: Levin, Charles Sawyers, Joseph Goldstein, David Baltimore, Eric Kandel, Elizabeth Blackburn, Elaine Fuchs, Robert Lefkowitz, and Alpern. Back row, from left: Peter Kim, Phillip Sharp, Harold Varmus, Michael Brown, and Michael Marmot. Speakers Robert Califf, Susan Lindquist, and Huda Zoghbi were unable to attend the dinner.

In an age of increasing emphasis on research explicitly directed toward treatments for human diseases, Lynn Cooley is a passionate advocate of basic, “curiosity-driven” research, which often provides insights that later prove useful in the clinic. Recent studies of ovarian muscle in the fruit fly Drosophila melanogaster in Cooley’s lab have shown that the fly could provide an important new model of human diseases such as muscular dystrophy.

Yale University President Richard Levin (center) joined neurosurgeon and geneticist Murat Günel (left) and financier Mehmet Kutman (right) at Woodbridge Hall to mark Kutman’s donation establishing the Yale Program in Brain Tumor Research. The new program will apply genomic techniques to the study of brain tumors, especially glioblastoma multiforme, the most common and most aggressive form of brain cancer.

From left: Miyoung Chung, vice president for scientific programs at the Kavli Foundation, and Robert W. Conn, Kavli Foundation president, joined Yale President Richard C. Levin and Pasko Rakic, director of the Kavli Center for Neuroscience at Yale, to mark the foundation’s renewed support for the center, which will expand its reach to embrace a broader range of neuroscience research at Yale.

Many of the speakers at the Bicentennial Symposium joined Yale President Richard Levin, Dean Robert Alpern, and medical school faculty for a dinner on April 28. (Front row, from left) Levin, Charles Sawyers, Joseph Goldstein, David Baltimore, Eric Kandel, Elizabeth Blackburn, Elaine Fuchs, Robert Lefkowitz, and Alpern. (Back row, from left) Peter Kim, Phillip Sharp, Harold Varmus, Michael Brown, and Michael Marmot. Symposium speakers Robert Califf, Susan Lindquist, and Huda Zogby were unable to attend the dinner.

Elizabeth Bradley (front, center) welcomes Chinese leaders in psychiatric care to the Yale GHLI-Fudan Mental Health Program.

Biomedical engineer Mark Saltzman, pictured with medical student Maya Kotas (left) and graduate student Margaret Cartiera, has developed a nanoparticle to deliver gene therapy. The particle has proven successful in vitro and in mouse models in introducing genes that thwart tumor cells while avoiding toxicity.

One of the world’s leading researchers in the cell biology of the synapse, Pietro De Camilli has catalogued and characterized a host of proteins involved in synaptic vesicle trafficking. Vesicles, which are crucial to brain function, are spherical sacs shaped from nerve cell membranes that are loaded with neurotransmitters. At synapses, vesicles fuse with the membrane and empty their cargo to send a chemical message. Then the membrane reshapes to form a new vesicle, and the cycle begins anew.

Marina Picciotto’s research not only sheds light on nicotine’s effects on the brain, but also has implications for for other important health issues, such as controlling obesity and the development of effective pain medications that do not lead to drug dependence.

During President Richard Levin’s 20-year tenure, biomedical science has flourished at Yale, with unprecedented increases in funding, research space, faculty hires, and the launch of novel interdisciplinary institutes.

Marina Picciotto is one of 70 American scientists elected in 2012 to the Institute of Medicine (IOM), “one of the highest honors in the fields of health and medicine [recognizing] individuals who have demonstrated outstanding professional achievement and commitment to service” according to the IOM website. Part of the National Academies, the IOM’s mission is “to provide unbiased and authoritative advice to decision makers and the public.”

Richard Levin (right) announced in August that he would step down after 20 years as president of Yale. Peter Salovey (left) was named to succeed him.

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