Richard Bucala MD, PhD

Professor of Medicine (Rheumatology), of Epidemiology (Microbial Diseases) and of Pathology and Residential College Associate Fellow in Faculty of Arts and Sciences

Departments & Organizations

Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Yale Medical Group

Cancer Immunology

Global Health Initiative: Infectious Diseases

School of Public Health: Parasitology Program

Skin Diseases Research Center, Yale

Pathology

Internal Medicine: Rheumatology | Diabetes Endocrinology Research Center

Research Interests

Mechanisms by which host immunity converts from a protective response to one producing disease and tissue pathology; Emergence of steroid resistance; Biochemical, biological, and genetic characterization of the MIF cytokine family; MIF's role in malaria and global infectious diseases; Pharmacologic immuniomodulation of the MIF pathway; Role of fibrocytes in different systemic fibroses

Clinical Interests

Autoimmune diseases; Rheumatoid arthritis; Systemic Fibroses; Y-NHH Consultation

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Education

B.S., Yale University , 1979
M.S., Yale University , 1979
Ph.D., Rockefeller University , 1985
M.D., Cornell College , 1986

Selected Publication

Sreih A, Ezzeddine R, Leng L, Lachance A, Yu G, Mizue Y, Subrahmanyan L, Pons-Estel BA, Abelson AK, Gunnarsson I, Svenungsson E, Cavett J, Glenn S, Zhang L, Montgomery R, Perl A, Salmon J, Alarcón-Riquelme ME, Harley JB, Bucala R. 2011. Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus. Arthritis Rheum. 63:3942-3951. PMCID: PMC3228269