Gerald I Shulman MD, PhD, FACP, FACE

George R. Cowgill Professor of Medicine (Endocrinology) and Professor of Cellular and Molecular Physiology; Investigator, Howard Hughes Medical Institute; Co-Director, Yale Diabetes Research Center; Director, Yale Mouse Metabolic Phenotyping Center

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Yale Medical Group

Office of Student ResearchMouse Metabolic Phenotyping CenterCellular & Molecular Physiology: Epithelial Transport of Ions and Solutes; Organ Physiology; Physiology of Human Disease; Physiology and Integrative Medical Biology Track; Graduate Program in Cellular and Molecular PhysiologyInternal Medicine: Endocrinology: Diabetes Center, Fellowship Training; Diabetes Research CenterCenter for X-Linked Hypophosphatemia, Yale


Dr. Shulman is Professor of Internal Medicine & Cellular and Molecular Physiology at Yale University, where he serves as Associate Director of the Yale Diabetes Endocrine Research Center and Associate Director of the Yale Medical Scientist (M.D., Ph.D.) Program. He is also an Investigator of the Howard Hughes Medical Institute. Dr. Shulman is an internationally recognized diabetes researcher, and the recipient of numerous awards, including the Outstanding Scientific Achievement Award and the Distinguished Clinical Scientist Award from the American Diabetes Association, the Diabetes Care Research Award from Boehringer-Mannheim/Juvenile Diabetes Foundation, and the Stanley Korsmeyer Award from the American Society for Clinical Investigation (ASCI). In addition to the ASCI Dr. Shulman is a Fellow of the American Association for the Advancement of Science and he has been elected to the American Society for Clinical Investigation, the Association of American Physicians, the Institute of Medicine and the National Academy of Sciences. He is a leading authority on the cellular mechanisms of insulin resistance, the role of the liver and muscle in the pathogenesis of type 2 diabetes, and the benefits of exercise in the management of diabetes. Dr. Shulman's practice is limited to the treatment of diabetes, and other disorders of glucose metabolism, with specific interests in the management of newly diagnosed type 2 diabetes mellitus.


  • BS, University of Michigan, Ann Arbor, MI , 1974
  • M.D., Wayne State University , 1979
  • Ph.D., Wayne State University , 1979

Selected Publication

  • Perry RJ, Kim T, Zhang XM, Lee HY, Pesta D, Popov VB, Zhang, D, Rahimi Y, Jurczak MJ, Cline GW, Spiegel DA, Shulman GI. Reversal of hypertriglyceridemia, fatty liver disease and insulin resistance by a liver-targeted mitochondrial uncoupler. Cell Metabolism. 2013;(18):740-48. PMID: 24206666. PMCID: 4104686.
Download on the Apple App Store