Rounds

Malaria makes a comeback, even in the U.S.

When two cases of malaria surfaced in New Haven late last year, they were of interest to clinicians not because of any epidemiological threat, but for the treatment problems they posed. Both cases were imported, rather than transmitted within North America. Both patients had contracted malaria during visits to West Africa to visit family. One was 24 weeks pregnant and one was found to be HIV-positive.

The clinicians treating the HIV-positive patient, according to Frank J. Bia, M.D., M.P.H., professor of medicine and laboratory medicine, speaking at grand rounds in January, were concerned about the interactions between HIV infection and malaria. In the case of the pregnant patient, noted Marissa Wilck, M.D., Winchester Fellow in Clinical Microbiology, clinicians were interested in the interaction of hemoglobinopathy and malaria. Ultrasound revealed the woman’s fetus to be healthy.

A...

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Ultrasound provides an alternative to amnio

Yale scientists have devised a test for fetal anemia that eliminates the risks of invasive procedures such as amniocentesis or cordocentesis. The test uses Doppler ultrasound to measure fetal blood velocity in the cerebral circulation. Anemic fetuses have a higher blood flow velocity in arteries and veins. “Invasive procedures place the fetus in unnecessary danger,” said Giancarlo Mari, M.D., associate professor of...

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Is it ever right to practice on the dying?

Early in 1998 a student approached Lauris C. Kaldjian, M.D., HS ’91, with a question about something disturbing seen on...

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Breast-cancer genes factor into treatment

Young women with breast cancer who carry either of two mutated genes may be at higher risk for a new cancer years after...

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Aspirin, on its own, shown to reduce heart-attack risk

An aspirin a day is as effective alone as with a powerful drug at preventing blood clotting in coronary vessels after a...

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Antibody test is a reliable screen for ehrlichiosis

A collaboration between scientists at Yale and the State of Connecticut has yielded a simpler and more reliable blood...

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Much heralded medication for autism is ineffective

A drug thought to work marvels on autistic children has no more effect than a placebo, according to a Yale...

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A new therapy for prostate cancer

A new radioactive isotope, palladium-103, used for radiation implant therapy for early prostate cancer has proven as...

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