Fred Gorelick MD
Professor of Medicine (Digestive Diseases) and of Cell Biology; Deputy Director, Yale M.D., Ph.D. Program
Departments & OrganizationsYale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development
Cell Biology: Membrane Traffic
Internal Medicine: Digestive Diseases
After completing medical school and internal medicine training at the University of Missouri, Dr. Gorelick trained at Yale in Gastroenterology. Afterhis clinical training, he began basic science training with Dr. James Jamieson at Yale. During that period he described calcium-calmodulin dependent protein kinase II and subsequently worked with Dr. Paul Greengard (Rockefeller University) to examines the enzyme's mechanism of activation, a response critical to memory.
His later work has focused on the mechanisms of acute pancreatits and how digestive enzymes, such as trypsin, are activated within the pancreas during this disease. Dr. Gorelick sees patients with gastrointestinal diseases at the VAMC in West Haven, CT. He is also the Deputy Director for the Yale physician Scientist program and directs a year-long course for the group that links basic science to clinical disease. He laboratory at the VA studies the molecular mechanisms related to acute pancreatitis with a goal of developing tools that prevent or lessen disease.