Fred Gorelick MD
Professor of Medicine (Digestive Diseases) and of Cell Biology; Associate Director, Yale M.D., Ph.D. Program

Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and DevelopmentCell Biology: Cancer cell biology
Internal Medicine: Digestive Diseases: Liver Center
Biography
After completing medical school and internal medicine training at the University, Dr. Gorelick came to Yale for a fellowship in gastroenterology. After completing his clinical training he began basic science training with Dr. James Jamieson at Yale. During that period he described calcium-calmodulin dependent protein kinase II. He subsequently worked with Dr. Paul Greengard (Rockefeller University) to demonstrate how this enzyme could become calcium-independent and function in memory.His later work has focused on the mechanisms of acute pancreatits and how digestive enzymes, such as trypsin, are activated within the pancreas during this disease. Dr. Gorelick sees patients with gastrointestinal diseases at the VAMC in West Haven, CT. He is also an Associate Director for the Yale physician Scientist program and directs a year-long course for the group that links basic science to clinical disease.
Education
- M.D., University of Missouri , 1973
Selected Publication
- Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F. Vacuolar-ATPase modulates MMP activities and invasive properties in human pancreatic ductal adenocarcinoma (PDAC). In Press, Laboratory Investigation NIHMS257466
Articles
Autumn 2006
Always put the patient first
The pressures of the real world will challenge their graduation-day idealism, Herbert S. Chase Jr., M.D., told the 101...

Autumn 2007
From the inner city to Yale and neurosurgery
An elite neurosurgeon born in crushing poverty, Benjamin Carson, M.D., told the Class of 2007 how learning transformed...



