Marie E Egan MD

Professor of Pediatrics (Respiratory) and Associate Professor of Cellular and Molecular Physiology; Director, Cystic Fibrosis Center


Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Stem Cells and Tissue Repair

Cellular & Molecular Physiology: Membrane Proteins - Ion Channels | Membrane Protein Sorting and Trafficking | Epithelial Transport of Ions and Solutes | Physiology of Human Disease | Physiology and Integrative Medical Biology Track | Graduate Program in Cellular and Molecular Physiology

Pediatrics: Pediatric Respiratory Medicine: Pediatric Asthma Program; Cystic Fibrosis Program, Pediatric | Pediatric Specialty Center | Pediatric Faculty Development Group

Research Interests

Cystic fibrosis clinical studies; Cystic fibrosis basic science research (ion transport, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) function); Cystic fibrosis translational research studies (strategies to bypass the basic defect)


Clinical Interests

Acute and chronic respiratory diseases; Asthma; Cystic fibrosis; Bronchopulmonary Dysplasia; Pneumonia; Congenital anomalies; Flexible bronchoscopy; Chronic ventilation; Sleep/sleep studies


Education

  • M.D., Mount Sinai School of Medicine , 1986

Selected Publication

  • Bruscia E., PX. Zhang, A. Satoh, C. Caputo, R. Medzhitov, A. Shenoy, M.E. Egan D.S. Krause. Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis, Journal of Immunology. 186: 6990-6998, 2011. (D.S.K. and M.E.E. contributed equally to this project and each should be considered as senior author.)

Latest Honor and Recognition

  • Society of Distinguished Teachers (2002) , Yale University School of Medicine