Matthew W. State MD, PhD

Donald J. Cohen Professor (Adjunct) in the Child Study Center and Professor of Genetics and of Psychiatry; Co-Director, Yale Program on Neurogenetics; Deputy Chairman for Research, Department of Psychiatry

Departments & Organizations

Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development: Genetics and Genomics

Yale Medical Group

Albert J. Solnit Integrated Training Program

Program in Neurodevelopment and Regeneration: Collaborators

Kavli Institute for Neuroscience

Child Study Center: Adjunct Faculty

Genetics

Psychiatry: Obsessive Compulsive Disorder Research Clinic

Research Interests

Genetic mechanisms; neuropsychiatric disorders of childhood

Clinical Interests

Child and adolescent psychiatry; genetic syndromes; Tourette's syndrome; Obsessive/Compulsive Disorder (OCD); developmental delay; mental retardation

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Education

M.D., Stanford University , 1991
Ph.D., Yale University School of Medicine , 2001

Selected Publication

Sanders SJ, Murtha MT, Gupta AR, Murdoch JD, Raubeson MJ, Willsey AJ, Ercan-Sencicek AG, DiLullo NM, Parikshak NN, Stein JL, Walker MF, Ober GT, Teran NA, Song Y, El-Fishawy P, Murtha RC, Choi M, Overton JD, Bjornson RD, Carriero NJ, Meyer KA, Bilguvar K, Mane SM, Sestan N, Lifton RP, Günel M, Roeder K, Geschwind DH, Devlin B, State MW (2012).De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature. 2012 Apr 4;485(7397):237-41. doi: 10.1038/nature10945

Articles

March/April 2008

Gene-hunters search the world for treatments

Yale researchers are going to the ends of the earth to find the genetic causes of human disease. The inspiration for...

Sept/Oct 2008

Genetics researcher is named inaugural Cohen Professor

Matthew W. State, M.D., Ph.D., an authority on the genetics of psychiatric disorders in children, has been named the...

July/August 2010

Faulty histamine gene is a factor in Tourette’s

Best known for triggering symptoms of hay fever, histamine also acts as a neurotransmitter in the brain. A new genetic...

Jan/Feb 2006

Making a major impact in Science

When French neurologist Gilles de la Tourette first cataloged the persistent muscle tics and involuntary vocal...

May 2012

A firm foothold in the genetics of autism

Matthew W. State, M.D., Ph.D., had never seriously considered a career in genetic research until 1995, when he spent a...

Sept/Oct 2012

Yale alum builds a crucial bridge for psychiatry researchers

Over the course of an eventful life, Herb Allison, M.B.A., a 1965 alumnus of Yale College, has found himself in many...

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