Mark B Gerstein PhD

Albert L. Williams Professor of Biomedical Informatics; Co-Director, Yale Computational biology and Bioinformatics Program

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Program in Neurodevelopment and Regeneration

Keck: NHLBI Proteomics | NIDA Neuroproteomics Center | High Performance Computation

Cancer Center, Yale: Cancer Genetics & Genomics

Center for RNA Science and Medicine, Yale

Molecular Biophysics and Biochemistry: Genomics, Genetics, and Bioinformatics


After graduating from Harvard summa cum laude with a A.B. in physics in 1989, Prof. Mark Gerstein earned a doctorate in biophysics and chemistry from Cambridge University in 1993. He did postdoctoral research in bioinformatics at Stanford University 1993-1996. He came to Yale in 1997 as an assistant professor in the Department of Molecular Biophysics and Biochemistry, and since 1999, in the computer science department. He was named an associate professor in 2001, and the following year became co-director of the Yale Computational Biology and Bioinformatics Program. In addition to the Keck Foundation grant, Prof. Gerstein has received Young Investigator Awards from the U.S. Navy, IBM, Pharmaceutical Research and Manufacturers of America, and the Donaghue Foundation. His other awards include a Herchel-Smith Scholarship supporting his doctoral work and a Damon Runyon-Walter Winchell Postdoctoral Fellowship. The author of numerous articles in scientific publications, Gerstein is editor of the Sequences and Topology section for the journal Current Opinion in Structural Biology. He also serves on the editorial boards of Functional and Integrative Genomics, the Journal of Structural and Functional Genomics, BioMed Central's Proteome Science and Genome Biology.


  • Ph.D., Cambridge University , 1992

Selected Publication

  • Yip KY, Kim PM, McDermott D, Gerstein M. BMC Bioinformatics. 2009 Aug 5;10(1):241. [Epub ahead of print]