Murat Gunel MD, FACS, FAHA
Nixdorff-German Professor of Neurosurgery and Professor of Genetics and of Neurobiology; Co-Director, Yale Program on Neurogenetics; Director, Neurovascular Surgery

Departments & Organizations
Gamma Knife Center, Yale-New HavenBiological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Neuroscience | Molecular Cell Biology, Genetics and Development
Interdepartmental Neuroscience Program
Yale Medical Group
Cancer Center, Yale
Vascular Biology and Therapeutics Program
Neurobiology
Genetics
Neurosurgery: Neurovascular Surgery | Brain Aneurysm & AVM Program
Brain Tumor Research
Biography
Dr. Murat Gunel, Professor of Neurosurgery, assumed the position of chief of Neurovascular Surgery Program in January of 2001. Dr. Gunel is a board certified neurosurgeon and is a fellow of the American College of Surgeons. He has special interest in treating brain aneurysms and vascular malformations with special emphasis on arterio-venous malformations and cavernous malformations. He also has expertise in occlusive vascular disorders such as carotid disease and gamma knife surgery (radiosurgery).His laboratory interests parallel his expertise in clinical neurovascular surgery and focus on gene discovery in disorders of the nervous system and its vasculature. Dr. Gunel's lab completed the two largest genome wide association studies (GWAS) aimed at understanding common variants that underlie intracranial aneurysm genetic risk based on the analysis of over 20,000 subjects. In addition, he is interested in the identification of genes important in human brain development through the study of rare, consanguineous families with recessive forms of malformations of cortical development.
Education
- M.D., Istanbul University , 1991
Selected Publication
- Bilgüvar K, Öztürk AK, Louvi A, Kwan KY, Choi M, Tatli B, Yalnizoglu D, Tüysüz B, Çaglayan AO, Gökben S, Kaymakçalan H, Barak T, Bakircioglu M, Yasuno K, Ho W, Sanders S, Zhu Y, Yilmaz S, Dinçer A, Johnson MJ, Bronen RA, Koçer N, Per H, Mane S, Pamir MN, Yalçinkaya C, Kumandas S, Topçu M, Özmen M, Šestan N, Lifton RP, State MW, Günel M: Whole exome sequencing identifies recessive mutations in severe brain malformations, Nature, 467(7312):207-10, 2010.
Latest Honor and Recognition
- Honorary Doctor of Philosophy Degree(2010) , Bahcesehir University, Turkey
Articles

March/April 2008
Gene-hunters search the world for treatments
Yale researchers are going to the ends of the earth to find the genetic causes of human disease. The inspiration for...

Nov/Dec 2009
Nixdorff-German Professor is neurosurgeon and geneticist
Murat Günel, M.D., recently named the Nixdorff-German Professor of Neurosurgery, combines a neurosurgical practice with...
May/June 2010
Zeroing in on genes to head off aneurysms
In a massive new genomic study, an international team led by School of Medicine researchers has identified three new...
May/June 2011
Small brains reveal a gene’s outsize role
Microcephaly is a developmental disorder characterized by significantly reduced brain size and a smaller number of...

March/April 2011
New line of attack on a dreaded disease
Few diseases are as feared, or as deadly, as glioblastoma multiforme (GBM), the most aggressive and most common form of...

March 2012
Center will study rare genetic diseases
For complex diseases like cancer and diabetes, there’s no crystal ball that can tell you for sure whether you’ll...


