Agnès M C Vignery DDS, PhD

Senior Research Scientist in Orthopaedics and Rehabilitation and in Cell Biology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development

Stem Cell Center, Yale: Stem Cell Niche and Homing

Vascular Biology and Therapeutics Program

Cell Biology: Membrane Traffic | Developmental Cell Biology and Genetics

Yale Core Center for Musculoskeletal Disorders

Orthopaedics and Rehabilitation

Immunology and Immunotherapy

Research Interests

Differentiation mechanism of osteoblasts; Fusion mechanism of macrophages


  • D.D.S., University of Paris , 1972
  • Ph.D., University of Paris , 1975

Selected Publication

  • Jin C, Frayssinet P, Pelker R, Cwirka D, Hu B, Vignery A, Eisenbarth SC, Flavell RA. NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathy. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14867-72. Epub 2011 Aug 19.