Jose Costa MD, FACP

Professor of Pathology and of Medicine (Medical Oncology); Director, Translational Diagnostics; Director, Musculoskeletal Tumor Program

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Cancer Center, Yale: Cancer Genetics & Genomics | Sarcoma Oncology Program

Skin Diseases Research Center, Yale

Pathology: Surgical Pathology: Bone and Soft-tissue Pathology; Pediatric Pathology | Molecular Diagnostics

Molecular Diagnostics

Gene Regulation and Functional Genomics

Research Interests

Oncology; Carcinogenesis; Tumor development and progression; Advanced diagnostics; Molecular diagnostics; Diagnosed genetic alterations in tumors; Cancer risk detection by mutational load distribution analysis

Clinical Interests

Molecular biology of tumors; oncologic pathology; molecular diagnostics; functional imaging; orthopaedic pathology; soft-tissue tumors; bone cancer; pediatric sarcomas; head and neck tumors.


  • M.D., University of Barcelona , 1967

Selected Publication

  • Costa, J., Gonzalez-Garcia, I., and Sole, R. (2006). Spatial Dynamics in Cancer, in Complex Systems Science in Biomedicine (Deisboeck, T.S., and Kresh, J.Y.), Chapter 6.2, pp. 557-572.