Stephen M Strittmatter MD, PhD
Vincent Coates Professor of Neurology and Professor of Neurobiology; Director, Cellular Neuroscience, Neurodegeneration and Repair; Director, Adler Memory Clinic in Neurology
Departments & Organizations
Program in Cellular Neuroscience, Neurodegeneration and Repair
Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development
Interdepartmental Neuroscience Program
Yale Medical Group
Neurobiology: Kavli Institute for Neuroscience | Strittmatter Lab
Neurology: Alzheimer's Disease/Dementia and Neuro-degenerative Disorders
Research Interests
Axon Guidance; Axon Regeneration; Spinal Cord Injury; Molecular Biology; Stroke; Neurodegenerative Disease; Alzheimer's Disease; Fronto-Temporal Dementia more...
Education
- AB, Harvard College, 1980
- M.D., Johns Hopkins University, 1986
- Ph.D., Johns Hopkins University, 1986
Selected Publications
- Akbik FV, Bhagat SM, Patel PR, Cafferty WB, Strittmatter SM. Anatomical plasticity of adult brain is titrated by nogo receptor 1. Neuron. 6:859-866 (2013).
- Um JW, Nygaard HB, Heiss JK, Kostylev MA, Stagi M, Vortmeyer A, Wisniewski T, Gunther EC, Strittmatter SM. Alzheimer Amyloid-ß Oligomer Bound to Post-Synaptic Prion Protein Activates Fyn to Impair Neurons. Nat Neurosci. 15: 1227-1235 (2012).
- Duffy P, Wang X, Seigel CS, Tu N, Henkemeyer M, Cafferty WBJ, Strittmatter SM. Myelin-Derived EphrinB3 Restricts Axonal Regeneration and Recovery after Adult CNS Injury. Proc. Natl. Acad. Sci. USA, 109:5063-5068 (2012).
Articles
May/June 2008
A scientific assault on brain diseases
The School of Medicine is home to outstanding research programs in cell biology and neurobiology, and members of its...
May/June 2009
A protein’s surprise role in Alzheimer’s
In 1906, the German psychiatrist Alois Alzheimer first described the disease that now bears his name, noting that...
March 2012
Heading off the ‘silent thief of sight’
About a decade ago, when Isobel Soukup went for a routine eye exam, her primary ophthalmologist discovered that the...
March 2013
Mapmakers of the living human body
Imagine trying to develop a drug and being able to see how and where that drug acts inside the body of a living person....
May 2012
Cycle of life
The poet William Carlos Williams exalted the ordinary: “So much depends,” he wrote, “upon/a red wheel/barrow.” Seen...
Jan/Feb 2010
‘Stimulus package’ grants saving jobs, building infrastructure, advancing research at Yale
The $787 billion American Recovery and Reinvestment Act of 2009 (ARRA), colloquially known as “the stimulus package,”...
July/August 2010
A familiar voice speaks up for Alzheimer’s patients, research
It began with a sweatshirt. In December 2007, when Tony- and Emmy-Award-winning actor David Hyde Pierce appeared on...
Jan/Feb 2006
Restoring flexibility to heal broken brains
In early life, the brain is continually sculpted by stimuli from the outside world. But soon, most neural circuits...
July/August 2010
Building a case against an Alzheimer’s culprit
In 2009, a team from the lab of Stephen M. Strittmatter, M.D., Ph.D., reported in Nature that small amyloid beta (A-β)...
May/June 2009
A continuous infusion of philanthropy
According to family lore, Ralph Falk, M.D., a physician and surgeon who practiced in Boise, Idaho in the early to...
Jan/Feb 2006
Neuroscientists target disorders of the brain and spinal cord
Neurodegenerative diseases, such as Alzheimer’s, Huntington’s and Parkinson’s, and injuries to the brain and spinal...
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