Stefan Somlo MD

C. N. H. Long Professor of Medicine (Nephrology) and Professor of Genetics; Chief, Section of Nephrology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology

Yale Medical GroupPhysiology of Human Disease | Graduate Program in Cellular and Molecular PhysiologyInternal Medicine: Nephrology: Center for Polycystic Kidney Disease Research | Genetics

Research Interests

Genetic kidney and liver disease; Cilia function in tissue homeostasis; Polycystin function

Clinical Interests

Polycystic kidney disease; inherited or familial kidney disease; genetic aspects of kidney disease; polycystic liver disease


  • B.A., Harvard University , 1980
  • M.D., Columbia University , 1984

Selected Publication

  • Fedeles SV, Tian X, Gallagher AR, Mitobe M, Nishio S, Lee SH, Cai Y, Geng L, Crews CM, Somlo S: A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet 43:639-647, 2011