Harvey J Kliman MD, PhD

Research Scientist in Obstetrics, Gynecology, and Reproductive Sciences; Director, Reproductive and Placental Research Unit


Departments & Organizations

Obstetrics, Gynecology & Reproductive Sciences: Recurrent Pregnancy Loss Program | Yale Fertility Center | Reproductive and Placental Research Unit

Women's Behavioral Health Research, Division of

Biography

Harvey J. Kliman has, in addition to an M.D., a Ph.D. in cellular biochemistry from the University of Chicago. He is currently a Research Scientist in the Department of Obstetrics and Gynecology, Yale University School of Medicine and the Director of the Reproductive and Placental Research Unit with a special interest in infertility and pregnancy complications. He has over thirty years of anatomic pathology training with particular emphasis in electron microscopy, immunohistochemistry, endometrial and placental pathology. He has over ten patents, including the patent for the Endometrial Function Test® (EFT®)—“The soil test for the endometrium®” and “Method and system for determining placental volume.” His contributions in the field of placental research include the development of the “Kliman” method of trophoblast purification, research into the mechanisms of trophoblast differentiation and invasion, the role and genesis of syncytial knots, the discovery of fetal fibronectin, and more recently, the clinical utility of abnormalities in placental villous growth patterns, especially trophoblast invaginations and inclusions, to diagnose genetic abnormalities in pregnancy, including autism.


Education

  • M.D., University of Chicago , 1980
  • Ph.D., University of Chicago , 1981

Selected Publication

  • Walker CK, Anderson KW, Milano KM, Ye S, Tancredi DJ, Pessah IN, Hertz-Picciotto I, Kliman HJ. (2013) Trophoblast Inclusions are Significantly Increased in the Placentas of Children in Families at Risk for Autism, Biological Psychiatry, http://dx.doi.org/10.1016/j.biopsych.2013.03.006