Joseph Schlessinger PhD, MSc
William H. Prusoff Professor of Pharmacology; Chair, Pharmacology; Director, Cancer Biology Institute

Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology: Cell Cycle and Signal Transduction; Drug Design, Discovery and Mechanism; Membrane Biology and MotionSignal Transduction
Structural Biology
Pharmacology: Schlessinger Lab: Investigator
Diabetes Endocrinology Research Center
Center for X-Linked Hypophosphatemia, Yale
Research Interests
Growth factor receptors; Intracellular signaling pathways;protein kinases; phosphorylation; SH2, SH3 and other protein modules involved in signal transduction; drug discovery
Education
- B.S., Hebrew University of Jerusalem , 1968
- M.Sc., Hebrew University of Jerusalem , 1969
- Ph.D., Weizmann Institute of Science, Isarel , 1974
Selected Publication
- M.A. Lemmon and J. Schlessinger. Cell signaling by receptor tyrosine kinases. Cell 141, 1117-1134 (2010).
Latest Honor and Recognition
- AACR International Award for Cancer(2010) , Penzcoller Foundation
Articles

July/August 2007
Finding a new chink in cancer’s armor
In the July 27 issue of Cell, a research team led by Joseph Schlessinger, Ph.D., William H. Prusoff Professor and chair...
Jan/Feb 2007
A scientist soldiers on
When Joseph Schlessinger, Ph.D., was born in Nazi-occupied Yugoslavia in 1945, gunfire crackled and shells exploded...

July/August 2007
Research center aims to make rickets history
When we think of rickets, the bone-softening disorder that causes short stature and bowing deformations of the legs,...
July/August 2006
Pioneer of antiviral therapies is awarded the Parker Medal, school’s highest honor
The Peter Parker Medal, the School of Medicine’s premier award, is named for an intrepid alumnus and graduate of the...

March/April 2006
Yale scientist shares $1 million Dan David prize for work on cell signaling and cancer
Though 2006 is not even half over, it’s already a year to remember for Joseph Schlessinger, Ph.D., chair and William H....

Jan/Feb 2010
Developer of new cancer drugs is honored with international award
Joseph Schlessinger, Ph.D., chair and William H. Prusoff Professor of Pharmacology, has been named winner of the 2010...

December 2010
Yale’s picks to beat cancer: a pair of aces
It has been an eventful December for the advancement of basic and translational cancer research at Yale. On the 13th,...

May/June 2011
New alliance with Gilead Sciences is ‘transformative’
When Robert J. Alpern, M.D., dean of the School of Medicine, was asked recently to prepare a brief overview of the...

July/August 2011
A young scientist scores another first
“This is the material that’s not in the biochemistry textbooks yet,” says Ya Ha, Ph.D. “This is preliminary work, but...

Jan/Feb 2006
Banner year for Yale as six on faculty join Institute of Medicine
Six Yale researchers, five with appointments at the School of Medicine and one from the School of Nursing, were among...


