John H. Krystal MD

Robert L. McNeil Jr. Professor of Psychiatry and Professor of Neurobiology; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Departments & Organizations



NIMH Research Training Program in Childhood-onset Neuropsychiatric Disorders

Diabetes Endocrinology Research Center

Psychiatry: Center for the Translational Neuroscience of Alcoholism | Obsessive Compulsive Disorder Research Clinic | Adult Psychiatry | VA Alcohol Research Center | VA National Center for PTSD


Dr. Krystal is a leading expert in the areas of alcoholism, schizophrenia, and post-traumatic stress disorders. His work links psychopharmacology, neuroimaging, and molecular genetics to study the neurobiology and to develop novel treatments for these disorders.

He is a member of the Institute of Medicine of the National Academy of Sciences. He also serves in a variety of advisory and review capacities for NIAAA, NIMH, Wellcome Trust, Brain and Behavior Research Foundation, and the Karolinska Institutet.

He previously served on the National Alcohol Abuse and Alcoholism Advisory Council (NIAAA), the Department of Defense Psychological Health Advisory Committee, the NIMH Board of Scientific Counselors (chair, 2005-2007), and American College of Neuropsychopharmacology (president, 2012).

Dr. Krystal also edits the journal, Biological Psychiatry (impact factor: 9.247).


  • B.A., University of Chicago , 1980
  • M.D., Yale University , 1984

Selected Publication

  • Jiang L, Gulanski BI, De Feyter HM, Weinzimer SA, Pittman B, Guidone E, Koretski J, Harman S, Petrakis IL, Krystal JH, Mason GF. Increased brain uptake and oxidation of acetate in heavy drinkers. J Clin Invest. 2013 Mar 8. doi:pii: 65153. 10.1172/JCI65153. [Epub ahead of print] PubMed PMID: 23478412.

Latest Honor and Recognition

  • Kempf Award for Contributions to Schizophrenia Research through Research and Mentorship(06/2005) , American Psychiatric Association