Flora Maria Vaccarino MD
Harris Professor in the Child Study Center and Professor of Neurobiology and Residential College Associate Fellow in Faculty of Arts and Sciences

Departments & Organizations
Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and DevelopmentInterdepartmental Neuroscience Program
Stem Cell Center, Yale: Stem Cell Genetics
Albert J. Solnit Integrated Training Program
Program in Neurodevelopment and Regeneration
Neurobiology: Kavli Institute for Neuroscience
Child Study Center: Tourette’s Syndrome & Obsessive-Compulsive Disorders | NIMH Research Training Program in Childhood-onset Neuropsychiatric Disorders | Child & Adolescent Psychiatry Training Program | Program in Neurodevelopment and Regeneration
Biography
Dr. Flora Vaccarino graduated in Medicine at Padua University in Italy and studied neuropharmacology and cell biology at NIH as a research fellow before starting her Residency in Psychiatry at Yale University. After her residency, she studied developmental biology and genetics and was appointed Assistant Professor at Yale University in 1994. She then pursued several lines of research, using genetic mouse models as well as human brain specimens, to understand the pathophysiology of neuropsychiatric disorders. Her 1999 paper in Nature Neuroscience (Vaccarino et al, 3: 246-253, 1999) showing that a single administration of Fibroblast Growth Factor 2 can induce permanent increases in cerebral cortical size, embodies the powerful role of these factors in development and plasticity.Together with people in her lab, Dr. Vaccarino, now a full Professor at Yale University School of Medicine, studies mouse and human neural stem cells and their role in development and repair. She and a group of colleagues recently founded the Program in Neurodevelopment and Regeneration to harness the power of induced pluripotent stem cells for understanding individual variation in neurodevelopment and the pathophysiology of neuropsychiatric disorders.
Education
- M.D., Padua University Medical University , 1979
Selected Publication
- Abyzov, A., Mariani, J., Palejev, D., Zhang, Y., Haney, M.S., Tomasini, L., Ferrandino, A., Rosenberg Belmaker, L., Szekely, A., Wilson, M., Kocabas, A., Calixto, N.E., Grigorenko, E.L., Huttner, A., Chawarska, K., Weissman, S., Eckehart Urban, A., Gerstein, M, & Vaccarino, F.M. Somatic copy-number mosaicism in human skin revealed by induced pluripotent stem cells. Nature, in press. doi: 10.1038/nature11629
Latest Honor and Recognition
- Harris Endowed Professorship(2010) , Child Study Center, Yale University School of Medicine
Articles

March 2013
Stem cells reveal a long-hidden mosaic
Although the many cells in a human body have distinct functions and appearances, it’s generally been assumed that they...

December 2010
Neuropsychiatrist, stem cell researcher is new Harris Professor of Child Psychiatry
Flora M. Vaccarino, M.D., who studies the pathophysiology of neuropsychiatric disorders and has elucidated how neural...


