PET Imaging in Cocaine Self Administration

Conditions

Cocaine Dependence

What is the purpose of this trial?

There has been recent interest in the role of the 5-HT1B receptor as a possible modulating factor in cocaine dependence, certainly in preclinical models. The Yale Positron Emission Tomography (PET) Center has developed a novel 5-HT1B receptor antagonist radioligand, [11C]-P943, which has been validated in human studies. We hypothesize that the 5-HT1B receptor plays a key role in cocaine dependence. The long term goal of this project would be to study pharmacological manipulation of the 5-HT1B receptor as a potential molecular target for cocaine dependence.


Participation Guidelines

Age:
18 Years - 50 Years
Gender:
Both

Click here for detailed information about who can participate in this trial.


Sponsor:
National Institute on Drug Abuse
Dates:
07/15/2014
Last Updated:
Study HIC#:
0811004457