Naltrexone and Memantine Effects on Alcohol Drinking Behaviors


Alcohol Drinking

What is the purpose of this trial?

The purpose of this study is to evaluate the combined effects of the study medications naltrexone and memantine on alcohol drinking behaviors. Participants will be randomized to receive a combination of these medications over a one week period and then participate in a laboratory session. During this session, participants are given an initial drink of alcohol followed by the choice to drink up to 12 more drinks over a three-hour period. These medications are hypothesized to reduce craving and number of drinks consumed prior to and after exposure to the initial drink of alcohol and during the three hour drinking period.

Participation Guidelines

21 Years - 50 Years

Click here for detailed information about who can participate in this trial.

National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Yale University
January 2012
Last Updated:
August 19, 2013
Study HIC#: ID: NCT01519063