Enhancing a High School Based Smoking Cessation Program


Nicotine Dependence

Trial Phase


Trial Purpose and Description

Trial Purpose

The purpose of this study is to examine the the efficacy of adjunctive nicotine replacement therapy when used in combination with the contingency management (CM) + cognitive behavioral therapy intervention. Subjects will be randomly assigned to receive either a nicotine transdermal patch or a placebo patch as well as being randomly assigned to receive either CM or no CM; all subjects will receive cognitive behavioral therapy. We hypothesize that that subjects receiving both active nicotine patch and CM will have higher rates of abstinence from tobacco than subjects in the other groups.

Participation Guidelines

14 Years - 19 Years

Eligibility Criteria

Inclusion Criteria:

- High School aged

- Desire to quit smoking

- Smoking >5 cigarettes per day

- Able to read and write in English

Exclusion Criteria:

- Current dependence on other substances

- Medical conditions that would contraindicate the use of a nicotine patch
National Institutes of Health (NIH)
Yale University
November 2009
Last Updated:
June 18, 2014
Study HIC#:

Clinicaltrials.gov ID: NCT01145001