Frederick Lewis Altice MD, MA

Professor of Medicine (Infectious Diseases) and of Epidemiology (Microbial Diseases); Director, Clinical and Community Research; Director, HIV in Prisons Program; Director, Community Health Care Van; Icon Professor of Medicine, University of Malaya-Centre of Excellence for Research in AIDS (CERiA); Professor of Epidemiology and Public Health, Division of Epidemiology of Microbial Diseases

Biographical Info

Frederick L. Altice is a professor of Medicine, Epidemiology and Public Health and is a clinician, clinical epidemiologist, intervention and implementation science researcher at Yale University School of Medicine and School of Public Health. Dr. Altice’s primary research project focuses on the interface between infectious diseases and substance use disorders and he has a special interest in Global Health. He also has a number of projects working in the criminal justice system, including transitional programs addressing infectious diseases, medication-assisted therapies (methadone, buprenorphine, extended release naltrexone), mental illness and social instability. Specific topics include alcohol and opioid use disorders on HIV treatment outcomes, HIV and substance abuse treatment, interface with the criminal justice system, and pharmacokinetic drug interactions between treatment for substance use disorders and antiretroviral and tuberculosis therapy. His research has focused on development of and evaluation of interventions to improve adherence to antiretroviral therapy. Newer research interventions are using mobile technology to improve engagement in treatment and to promote medication adherence. Additionally, his research, using health services research techniques and implementation science, seeks to understand integration of methadone, buprenorphine and extended released naltrexone and its role in primary and secondary HIV prevention, including linkage to and retention in care. His work has emerged primarily with a global health focus with funded research projects internationally in Malaysia, Ukraine, Russia, Central Asia, Peru, and Indonesia. He has participated in projects through the National Institute on Alcohol Abuse and Alcoholism, the National Institute on Drug Abuse, Centers for Disease Control and Prevention, Substance Abuse and Mental Health Services Agency and the Center for Substance Abuse Treatment. He is currently also collaborating on projects with the WHO, UNAIDS, USAID, PEPFAR and UNODC. Current internationally funded projects in dedicated research sites that are being conducted in Malaysia, Ukraine, Moldova, Azerbaijan, Kyrgyzstan and Peru. His sites in Malaysia, Peru and Ukraine are dedicatedsites for the Global Health Equity Scholars Fogarty Training Program and the Doris Duke International Fellowship program.


International Activity

  • Studies of Alcohol and Drug Use Among MSM in Peru
    Lima, Peru   (2011 - 2016)
    Biobehavioral Surveys, RCTs of XR-NTX among HIV+ MSM with alcohol use disorders and RCTs of early vs late initiation of ART among newly seroconverted MSM. This is a Fogarty International Global Health Equity Scholars site.
  • HIV, Opioid, Substance abuse, Malaysia
    Malaysia   (2010)
    Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia
  • HIV, Tuberculosis and Drug Dependence In Iran
    Iran   (2009)
    This involves three projects: 1. HIV and TB Coinfection Among Drug Users in Iran 2. Treatment for Opioid Dependence Among Individuals with HIV or TB 3. Prisoners and Methadone Maintenance.
  • Opioid Dependence and HIV in Malaysia
    Malaysia   (2009)
    In 2005, the Malaysian government changed its policies toward substance abuse by implementing syringe exchange programs and methadone maintenance programs. Professor Altice has been a consultant in developing and evaluating the new policies and have since begun several different studies in Malaysia at the interface of substance abuse and infectious diseases, including involvement with the Prison Ministry. Collaboration through the University of Malaysia.
  • Opioid Dependence and HIV in Ukraine
    Ukraine   (2005)
    Since 2005, Professor Altice have trained the physicians on treatment of opioid dependence, HIV and tuberculosis. Specifically, in collaboration with his Ukrainian colleagues, They introduced the first pilot buprenorphine treatment programs in the country. They are now participating in the establishment and expansion of methadone maintenance treatment and how integrated health services can be developed that target substance abuse, HIV and tuberculosis. Currently, there are two NIH funded research projects. One is to expand medication assisted therapies in Ukraine, while the other is to introduce and expand evidence-based intervention for prisoners in Ukraine and Central Asia. This is a Fogarty International Global Health Equity Scholars site.
  • Infectious Diseases and Addiction
    Kuala Lumpur, Malaysia   (2005)
    Funded Research Activities with Centre of Excellence in Research on AIDS (CERiA). Projects are extensive and include epidemiological studies with vulnerable populations including prisoners, female sex workers, men who have sex with men and people who inject drugs. Current studies also include those involving HIV, TB, substance abuse and intervention research. This is a Fogarty International Global Health Equity Scholars site.
  • HIV/AIDS, Tuberculosis and Addiction
    Ukraine   (2005)
    Technical Assistance and Research, Developed integrated health care delivery system, Rolled out buprenorphine and methadone

Education & Training

M.D.
Emory University (1986)
Resident
Yale University School of Medicine, Infectious Diseases 
Fellow
Yale University School of Medicine, Infectious Diseases 
Board Certification
Internal Medicine, Board Certified  (1989)

Honors & Recognition

  • National Hope is a Vaccine" Award Recipient
    GAIA, Global Alliance to Immunize against AIDS (2008)
  • Appointed as Icon Professor of Medicine, Centre for Excellence in Research in AIDS (CERiA) at University of Malaya
    Infectious Diseases Unit, Department of Medicine, Faculty of Medicine, University of Malaya (2009)
  • Board of Permanent Officers
    Yale University School of Medicine (2009)

Professional Service

  • Member (2009 - pres)
  • Chair (2009 - pres)
  •  (2009)
  • Member (2008 - pres)
  • Journal Reviewer (2008 - pres)
  • Editorial Board (2008 - pres)
  •  (2008 - pres)
  •  (2007 - pres)
  • Member (2005 - pres)
  • Journal Reviewer (2005 - pres)
  • Member (2004 - pres)
  • Journal Reviewer (2003 - pres)
  •  (2002 - pres)
  • Member (2001 - pres)
  • Permanent Member (2001 - pres)
  • Member (1997 - pres)
  • Member (1994 - pres)
  • Fellow (1993 - pres)
  • Member (1993 - pres)
  • Member (1992 - pres)

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