Kathleen M. Carroll PhD

Albert E. Kent Professor of Psychiatry; Director of Psychosocial Research, Division of Addictions; Principal Investigator, Psychotherapy Development Center for Drug Abuse

Research Interests

Addiction and treatment; Evidence-based treatments; Treatment development; Computer-assisted therapies; Research-practice partnerships; Clinician training; Psychotherapy-pharmacotherapy combinations; Neurocognitive effects of behavioral therapies

Current Projects

Principal Investigator:

  • NIDA U10 “Clinical Trials Network: New England Node”
  • NIDA K05 “Psychotherapy of Substance Use Disorders”
  • NIDA R37 (NIH MERIT award) Computer Based Training in Cognitive Behavioral Therapy:
  • NIDA P50 Psychotherapy Development Center.
  • NIDA R01 CBT4CBT for Spanish Speakers (with Dr. Manny Paris)

Research Summary

My long-term goal is to improve the effectiveness of addiction treatment through:

  • More precise understanding of the treatments and mechanisms that produce the best outcomes in substance abusers;
  • Development, refinement, and evaluation of innovative behavioral approaches;
  • Working to increase the methodological quality of research in the field of substance abuse;
  • Evaluating effective means of transferring new technologies and fostering broader use of empirically supported treatments by the clinical community;
  • Training new researchers in the most rigorous methodology of treatment outcome research.

Current interests include computer-based treatments and training (CBT4CBT)


Selected Publications

  • Carroll, K.M., Kiluk, B.D., Nich, C., DeVito, E.E., Decker, S., LaPaglia, D., Duffey, D., Babuscio, T.A. & Ball, S.A. (2014). Towards empirical identification of a reliable and clinically meaningful indicator of treatment outcome for illicit drug use. Drug and Alcohol Dependence, 137, 3-19
  • Carroll, K.M, Kiluk, B.D., Nich, C., Gordon, M.A., Portnoy, G.A., Martino, D.R., & Ball, S.A. (2014). Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and durability of CBT4CBT among cocaine-dependent individuals maintained on methadone. The American Journal of Psychiatry, 171, 436-444
  • Kiluk, B.D.., Sugarman, D.E., Nich, C., Gibbons, C.R., Martino, S., Rounsaville, B.J. & Carroll, K.M. (2011). A methodological analysis of randomized clinical trials of computer-assisted therapies for psychiatric disorders: Towards improved standards for an emerging field. American Journal of Psychiatry, 168: 790-799.
  • Carroll, K.M., Ball, S.A., Martino, S., Nich, C., Babuscio, T. A. & Rounsaville, B.J. (2009). Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A six-month follow-up of CBT4CBT. Drug and Alcohol Dependence, 100, 178-181. NIHMS ID: 93825
  • Carroll, K.M., Ball, S.A., Martino, S. Nich, C., Gordon, M.A., Portnoy, G.A. & Rounsaville, B.J. (2008). Computer-assisted delivery of cognitive behavioral therapy for addiction: A randomized trial of CBT4CBT. The American Journal of Psychiatry, 165:7, 881-889. PMCID: 2562873
  • Carroll, K.M. & Rounsaville, B.J. (2007). A vision of the next generation of behavioral therapies research in the addictions. Addiction, 102, 850-862. PMCID: 2148498
  • Carroll, K.M. & Onken, L.S. (2005). Behavioral therapies for drug abuse (invited review for Special Series honoring 30th Anniversary of NIDA). American Journal of Psychiatry, 162, 1452-1460
  • Carroll, K.M., Fenton, L.R., Ball, S.A., Nich, C., Frankforter, T.L., Shi, J. & Rounsaville, B.J. (2004). Efficacy of disulfiram and cognitive-behavioral therapy in cocaine-dependent outpatients: A randomized placebo-controlled trial. Archives of General Psychiatry, 61, 264-272.
  • Carroll, K.M., Ball, S.A., Nich, C., O’Connor, P.G., Eagan, D., Frankforter, T.L., Triffleman, E.G., Shi, J. & Rounsaville, B.J. (2001). Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: Efficacy of contingency management and significant other involvement. Archives of General Psychiatry, 58, 755-761.
  • Carroll, K.M., Rounsaville, B.J., Nich, C., Gordon, L.T., Wirtz, P.W., & Gawin, F.H. (1994). One year follow-up of psychotherapy and pharmacotherapy for cocaine dependence: Delayed emergence of psychotherapy effects. Archives of General Psychiatry, 51, 989-997.

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