Seth R Axelrod PhD

Associate Professor of Psychiatry; Dialectical Behavior Therapy Team Leader at the Yale-New Haven Psychiatric Hospital Intensive Outpatient Program

Research Interests

Borderline personality disorder and comorbid conditions (e.g., substance use disorders, PTSD); Adaptations of Dialectical Behavior Therapy (DBT); Mindfulness; Emotion regulation; DBT Formulation; Burnout

Current Projects

Current Research collaborations include:
  • Dialectical Behavior Therapy modified for Children
  • Cognitive and Emotion Regulation Process in Borderline Personality Disorder
  • Associations of Iraq deployment and combat-related PTSD with Borderline Personality Disorder features

Research Summary

My primary clinical, research, and training interests center around personality disorders, with a focus on borderline personality disorder and Dialectical Behavior Therapy (DBT). I am particularly interested in adaptations of DBT, including DBT modified for the day hospital setting, for comorbid borderline personality disorder and substance use disorders, and for children with suicidal and self-injurious behaviors. My other research interests include trauma, PTSD, mindfulness, and emotion regulation.


Selected Publications

  • Axelrod, S. R., & Lee, J. (2013). Applying Dialectical Behavior Therapy Methods to Personality Disorder Patients in Healthcare Settings. Asia Health Care Journal, 1, 5-10.
  • Perepletchikova, F., Ansell, E. B., & Axelrod, S. R. (2012). Borderline personality disorder features and history of childhood maltreatment in mothers involved with child protective services. Child Maltreatment, 17, 182-190.
  • Axelrod, S. R., Perepletchikova, F., Holtzman, K., & Sinha, R. (2011). Emotion Regulation and Substance Use Frequency in Women with Substance Dependence and Borderline Personality Disorder Receiving Dialectical Behavior Therapy. American Journal of Drug and Alcohol Abuse, 37, 37-42.
  • Perepletchikova, F., Axelrod, S. R., Kaufman, J., Rounsaville, B. J., Douglas-Palumberi, H., & Miller, A. L. (2011). Adapting dialectical behavior therapy for children: Towards a new research agenda for Paediatric suicidal and non-suicidal self-injurious behaviors. Child and Adolescent Mental Health. 16, 116–121.
  • Wupperman, P., Neumann, C. S., Whitman, J., & Axelrod, S. R. (2009). The role of mindfulness in borderline personality disorder features. Journal of Nervous and Mental Disease, 197, 766-71.
  • Wupperman, P., Neumann, C. S., & Axelrod, S. R. (2008). Do deficits in mindfulness underlie borderline personality features and core difficulties? Journal of Personality Disorders, 22, 466-482.
  • Fox, H. C., Axelrod, S. R., Paliwal, P., Sleeper, J., & Sinha, R. (2007). Difficulties in emotion regulation and impulse control during cocaine abstinence. Drug and Alcohol Dependence, 89, 298-301.
  • Axelrod, S. R., Morgan, C. A., & Southwick, S. M. (2005) Symptoms of posttraumatic stress disorder and borderline personality disorder features in veterans of operation desert storm. American Journal of Psychiatry,162, 270-275.
  • Southwick, S. M., Axelrod, S. R., Wang, S. Yehuda, R., Morgan III, C. A., Charney, D., Rosenheck. R., & Mason, J. (2003). Twenty-four hour urine cortisol in combat veterans with PTSD and comorbid borderline personality disorder. Journal of Nervous and Mental Disease, 191, 261-262.
  • Sanislow, C. A., Grilo, C. M., Fehon, D., Axelrod, S. R., & McGlashan, T. H. (2003). Correlates of suicide risk in juvenile detainees and adolescent inpatients. Journal of the American Academy of Child and Adolescent Psychiatry. 42, 234-240.

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