Affective Disorders, Psychotic; Schizophrenia and Disorders with Psychotic Features
The main area of research interest has been investigating neurochemical underpinning of schizophrenia. More specifically, investigating effects and interactions of various psychoactive chemicals inducing clinical characteristics of schizophrenia or inducing vulnerability to psychosis in human subjects. In this context, I have involved in several challenge studies using ketamine, iomezanil, and amphetamine during my residency training at Seoul National University and postdoctoral fellowship at the VA-Yale schizophrenia research program. I also have some expertise in neuro-imaging studies from experience as a research fellow at Brain Imaging Center at McLean Hospital, Harvard Medical School. Currently, I am conducting study, as a PI, investigating interactive effects of GABA and Dopamine system in schizophrenia.
- N-methyl-D-aspartate receptor in working memory impairments in schizophrenia: event-related potential study of late stage of working memory process. Prog Neuropsychopharmacol Biol Psychiatry
- White matter hyperintensities in subjects with bipolar disorder. Psychiatry Clin Neurosci.
- Probing GABA receptor function in schizophrenia with iomazenil. Neuropsychopharmacology
- Role of GABA Deficit in Sensitivity to the Psychotomimetic Effects of Amphetamine. Neuropsychopharmacology