John H. Krystal MD

Robert L. McNeil Jr. Professor of Psychiatry and Professor of Neurobiology; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Departments & Organizations



NIMH Research Training Program in Childhood-onset Neuropsychiatric Disorders

Diabetes Endocrinology Research Center

Psychiatry: Center for the Translational Neuroscience of Alcoholism | Obsessive Compulsive Disorder Research Clinic | Adult Psychiatry | VA Alcohol Research Center | VA National Center for PTSD

Research Interests

Neurobiology; Pharmacotherapy; Genetics; Neuroimaging; Schizophrenia; Alcoholism; PTSD more...


  • B.A., University of Chicago, 1980
  • M.D., Yale University, 1984

Selected Publications

  • Jiang L, Gulanski BI, De Feyter HM, Weinzimer SA, Pittman B, Guidone E, Koretski J, Harman S, Petrakis IL, Krystal JH, Mason GF. Increased brain uptake and oxidation of acetate in heavy drinkers. J Clin Invest. 2013 Mar 8. doi:pii: 65153. 10.1172/JCI65153. [Epub ahead of print] PubMed PMID: 23478412.
  • Murray JD, Anticevic A, Gancsos M, Ichinose M, Corlett PR, Krystal JH, Wang XJ. Linking Microcircuit Dysfunction to Cognitive Impairment: Effects of Disinhibition Associated with Schizophrenia in a Cortical Working Memory Model. Cereb Cortex. 2012 Nov 29. [Epub ahead of print] PubMed PMID: 23203979.
  • Anticevic A, Cole MW, Murray JD, Corlett PR, Wang XJ, Krystal JH. The role of default network deactivation in cognition and disease. Trends Cogn Sci. 2012 Dec;16(12):584-92. doi: 10.1016/j.tics.2012.10.008. PubMed PMID:23142417; PubMed Central PMCID: PMC3501603.



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