Christopher H Van Dyck, MD

Professor of Psychiatry, Neurology, and Neuroscience; Director, Alzheimer's Disease Research Unit; Director, Yale Alzheimer's Disease Research Center; Director, Division of Aging and Geriatric Psychiatry

Clinical Interests

  • Alzheimer Disease

Patient Care

Accepts new patients? Yes
Patient Type: Geriatric
Referrals: From patients or physicians

Patient Care Organizations

Psychiatry: Alzheimer's Disease Research Unit

Dorothy Adler Geriatric Assessment Center

Yale Medicine

Office of Cooperative Research

Clinical Trials

Conditions Study Title
Alzheimer's Disease An Efficacy and Safety Study of JNJ-54861911 in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia (EARLY)
Alzheimer's Disease Exercise in Adults With Mild Memory Problems (EXERT)
Alzheimer's Disease Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol (ADNI3)
Alzheimer's Disease A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (Generation)
Alzheimer's Disease A Study of LY3314814 in Participants With Mild Alzheimer's Disease Dementia (DAYBREAK-ALZ)
Alzheimer's Disease CREAD Study: A Study of Crenezumab Versus Placebo to Evaluate the Efficacy and Safety in Participants With Prodromal to Mild Alzheimer's Disease (AD)
Alzheimer's Disease Apathy in Dementia Methylphenidate Trial 2 (ADMET2)
Alzheimer's Disease 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease (EMERGE)
Alzheimer's Disease Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. (DIAN-TU)

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Contact Info

Christopher H Van Dyck, MD
Patient Care Locations
Yale Alzheimer's Disease Research Unit1 Church Street, Ste Suite 600
New Haven, CT 06510
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Adler Geriatric Assessment Center874 Howard Avenue
New Haven, CT 06519
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Mailing Address
Yale University School of Medicine
One Church Street

New Haven, CT 06510

Alzheimer's Disease Research Unit

Research Image 1

Frequency of psychosis by ApoE e4 carrier status and dementia severity. Mini Mental State Examination (MMSE) score was used to classify AD patients as mild (MMSE>19, n=103), moderate (MMSE=12-19, n=121), or severe (MMSE<12, n=42). Separate multiple logistic regression analyses were performed for each severity category, with presence of psychosis as dependent variable and the following independent variables (in addition to e4 carrier status): age, sex, educational attainment, and MMSE. *Only at the severe stage was the presence of e4 significantly associated with psychosis (odds ratio [OR]=16.61, 95% CI=2.11-130.51, P=.008). (From Zdanys KF , et al. 2007.)