Angus Clark Nairn, PhD

Charles B. G. Murphy Professor of Psychiatry and Professor of Pharmacology

Contact Info

Angus Clark Nairn, PhD
Mailing Address
Department of Psychiatry300 George St
New Haven, CT 06511-
Research Image 2

Beyond the Dopamine Receptor: Regulation and Roles of Serine/Threonine Protein Phosphatases: Left Panels: DARPP-32 (left, saggital section, positive immunoreactivity black), RCS (middle, coronal section, positive immunoreactivity white; caudate/putamen (CP) and nucleus accumbens (A); inset at right shows RCS enrichment in nucleus accumbens (left of dashed line) in more rostral section, ARPP-16 (right, saggital section, immunoreactivity white). Simple domain diagrams of each protein with their amino acid number and site of PKA phosphorylation are shown below the respective immunolocalization panels. Right Panel: Interactive roles of DARPP-32, RCS and ARPP-16 in regulation of signal transduction in striatal neurons.