Alan S Lewis, MD, PhD

Research Interests

Research Summary

Aggression is comorbid with numerous neuropsychiatric disorders across the lifespan. Understanding is limited as to how such conditions might increase predisposition to aggression. Furthermore, treatment for aggression, which includes both behavioral and pharmacological approaches, can be incompletely effective, and in the case of pharmacotherapy, places patients at high risk for serious side effects. The overall goal of my current research is to identify how the nicotinic acetylcholinergic receptor system governs aggressive behavior in preclinical models, with the ultimate goal of translating these findings into improved treatments for clinical populations.

Selected Publications

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