Selected Recent Publications

Bloch, MH, Panza, KE, Grant, JE, Pittenger, C, Leckman, JF.  N-Acetylcysteine in the treatment of pediatric trichotillomania: A randomized, double-blind, placebo-controlled add-on trial. Journal of the American Academy of Child & Adolescent Psychiatry. 2013; 52 (3): 231-240

Bloch, M, State, M, Pittenger, C. Recent advances in Tourette syndrome. Current Opinion in Neurology. 2011;24:119-125.

Jakubovski, E, Pittenger, C, Torres, AR, Fontenelle, LF, do Rosario, MC, Ferrao, YA, de Mathis, MA, Miguel, EC, Bloch, MH. Dimensional correlates of poor insight in obsessive-compulsive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2011;35:1677-1681.

Landeros-Weisenberger, A, Bloch, MH, Kelmendi, B, Wegner, R, Nudel, J, Dombrowski, P, Pittenger, C, Krystal, JH, Goodman, WK, Leckman, JF, Coric, C. Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder. Journal of Affective Disorders. 2010;121:175-179.

Palermo, SD, Bloch, MH, Craiglow, B, Landeros-Weisberger, A, Dombrowski, PA, Panza, K, Smith, ME, Peterson, BS, Leckman, JF. Predictors of early adulthood quality of life in children with obsessive compulsive disorder. Social Psychiatry and Psychiatric Epidemiology. 2011;46:291-297.

Pittenger, C, Bloch, MH, Williams, K. Glutamate abnormalities in obsessive-compulsive disorder: Neurobiology, pathophysiology, and treatment. Pharmacology & Therapeutics. 2011;132:314-332.

Pittenger, C, Coric, V, Banasr, M, Bloch, M, Krystal, JH, Sanacora, G. Riluzole in the treatment of mood and anxiety disorders. CNS Drugs. 2008;22:761-786.

Publications

Bloch MH and Mulqueen J: Nutritional supplements for the treatment of ADHD. Child Adolesc Psychiatr Clin N Am. 2014 Oct;23 (4) :883-97. Epub 2014 Aug 12. PMID: 25220092


Pittenger C and Bloch MH: Pharmacological treatment of obsessive-compulsive disorder. Psychiatr Clin North Am. 2014 Sep;37 (3) :375-91. Epub 2014 Jul 24. PMID: 25150568


Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrió GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ and Pauls DL: Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD. Am J Psychiatry. 2014 Aug 26; Epub 2014 Aug 26. PMID: 25158072


McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K and Scharf JM: Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. J Am Acad Child Adolesc Psychiatry. 2014 Aug;53 (8) :910-9. Epub 2014 Jun 24. PMID: 25062598


Adelman CB, Panza KE, Bartley CA, Bontempo A and Bloch MH: A meta-analysis of computerized cognitive-behavioral therapy for the treatment of DSM-5 anxiety disorders. J Clin Psychiatry. 2014 Jul;75 (7) :e695-704. PMID: 25093485


Jakubovski E and Bloch MH: Prognostic subgroups for citalopram response in the STAR*D trial. J Clin Psychiatry. 2014 Jul;75 (7) :738-47. PMID: 24912106


Yang GJ, Murray JD, Repovs G, Cole MW, Savic A, Glasser MF, Pittenger C, Krystal JH, Wang XJ, Pearlson GD, Glahn DC and Anticevic A: Altered global brain signal in schizophrenia. Proc Natl Acad Sci U S A. 2014 May 20;111 (20) :7438-43. Epub 2014 May 5. PMID: 24799682


Anticevic A, Hu S, Zhang S, Savic A, Billingslea E, Wasylink S, Repovs G, Cole MW, Bednarski S, Krystal JH, Bloch MH, Li CS and Pittenger C: Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder. Biol Psychiatry. 2014 Apr 15;75 (8) :595-605. Epub 2013 Nov 4. PMID: 24314349


Bloch MH: Meta-analysis and moderator analysis: can the field develop further? J Am Acad Child Adolesc Psychiatry. 2014 Feb;53 (2) :135-7. PMID: 24472248


Castellan Baldan L, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, Ohtsu H, Bloch MH, Hughes ZA, Krystal JH, Mayes L, de Araujo I, Ding YS, State MW and Pittenger C: Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice. Neuron. 2014 Jan 8;81 (1) :77-90. PMID: 24411733


Scheinost D, Stoica T, Wasylink S, Gruner P, Saksa J, Pittenger C and Hampson M: Resting state functional connectivity predicts neurofeedback response. Front Behav Neurosci. 2014;8 :338. Epub 2014 Sep 24. PMID: 25309375


Lee AS, André JM and Pittenger C: Lesions of the dorsomedial striatum delay spatial learning and render cue-based navigation inflexible in a water maze task in mice. Front Behav Neurosci. 2014;8 :42. Epub 2014 Feb 13. PMID: 24592223

Pittenger C: Disorders of memory and plasticity in psychiatric disease. Dialogues Clin Neurosci. 2013 Dec;15 (4) :455-63. PMID: 24459412


Driesen NR, McCarthy G, Bhagwagar Z, Bloch MH, Calhoun VD, D'Souza DC, Gueorguieva R, He G, Leung HC, Ramani R, Anticevic A, Suckow RF, Morgan PT and Krystal JH: The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity. Neuropsychopharmacology. 2013 Dec;38 (13) :2613-22. Epub 2013 Jul 16. PMID: 23856634


Sukhodolsky DG, Bloch MH, Panza KE and Reichow B: Cognitive-behavioral therapy for anxiety in children with high-functioning autism: a meta-analysis. Pediatrics. 2013 Nov;132 (5) :e1341-50. Epub 2013 Oct 28. PMID: 24167175


Zebardast N, Crowley MJ, Bloch MH, Mayes LC, Wyk BV, Leckman JF, Pelphrey KA and Swain JE: Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: initial findings. Psychiatry Res. 2013 Oct 30;214 (1) :33-41. Epub 2013 Jul 31. PMID: 23916249


Reichow B, Volkmar FR and Bloch MH: Systematic review and meta-analysis of pharmacological treatment of the symptoms of attention-deficit/hyperactivity disorder in children with pervasive developmental disorders. J Autism Dev Disord. 2013 Oct;43 (10) :2435-41. PMID: 23468071


Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Mesa Restrepo SC, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosàrio MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Valencia Duarte AV, Vallada H, Van Nieuwerburgh F, Veenstra-Vanderweele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ and Scharf JM: Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet. 2013 Oct;9 (10) :e1003864. Epub 2013 Oct 24. PMID: 24204291


Mulqueen JM, Bartley CA and Bloch MH: Meta-Analysis: Parental Interventions for Preschool ADHD. J Atten Disord. 2013 Sep 26; Epub 2013 Sep 26. PMID: 24071773


Bloch MH, Green C, Kichuk SA, Dombrowski PA, Wasylink S, Billingslea E, Landeros-Weisenberger A, Kelmendi B, Goodman WK, Leckman JF, Coric V and Pittenger C: Long-term outcome in adults with obsessive-compulsive disorder. Depress Anxiety. 2013 Aug;30 (8) :716-22. Epub 2013 Mar 26. PMID: 23532944


Bartley CA and Bloch MH: Meta-analysis: pharmacological treatment of pathological gambling. Expert Rev Neurother. 2013 Aug;13 (8) :887-94. Epub 2013 Aug 16. PMID: 23952195


Bartley CA, Hay M and Bloch MH: Meta-analysis: aerobic exercise for the treatment of anxiety disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45 :34-9. Epub 2013 Apr 30. PMID: 23643675


Niciu MJ, Grunschel BD, Corlett PR, Pittenger C and Bloch MH: Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive-compulsive disorder and a history of major depressive disorder. J Psychopharmacol. 2013 Jul;27 (7) :651-4. Epub 2013 May 15. PMID: 23676198


Cohen SC, Leckman JF and Bloch MH: Clinical assessment of Tourette syndrome and tic disorders. Neurosci Biobehav Rev. 2013 Jul;37 (6) :997-1007. Epub 2012 Dec 1. PMID: 23206664


Weisman H, Qureshi IA, Leckman JF, Scahill L and Bloch MH: Systematic review: pharmacological treatment of tic disorders--efficacy of antipsychotic and alpha-2 adrenergic agonist agents. Neurosci Biobehav Rev. 2013 Jul;37 (6) :1162-71. Epub 2012 Oct 23. PMID: 23099282


Kichuk SA, Torres AR, Fontenelle LF, Rosário MC, Shavitt RG, Miguel EC, Pittenger C and Bloch MH: Symptom dimensions are associated with age of onset and clinical course of obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 1;44 :233-9. Epub 2013 Feb 12. PMID: 23410525


Ferracioli-Oda E, Qawasmi A and Bloch MH: Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8 (5) :e63773. Epub 2013 May 17. PMID: 23691095


Quinn JJ, Pittenger C, Lee AS, Pierson JL and Taylor JR: Striatum-dependent habits are insensitive to both increases and decreases in reinforcer value in mice. Eur J Neurosci. 2013 Mar;37 (6) :1012-21. Epub 2013 Jan 9. PMID: 23298231


Panza KE, Pittenger C and Bloch MH: Age and gender correlates of pulling in pediatric trichotillomania. J Am Acad Child Adolesc Psychiatry. 2013 Mar;52 (3) :241-9. PMID: 23452681


Bloch MH, Panza KE, Grant JE, Pittenger C and Leckman JF: N-Acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial. J Am Acad Child Adolesc Psychiatry. 2013 Mar;52 (3) :231-40. PMID: 23452680


Frick LR, Williams K and Pittenger C: Microglial dysregulation in psychiatric disease. Clin Dev Immunol. 2013;2013 :608654. Epub 2013 Apr 18. PMID: 23690824


Qawasmi A, Landeros-Weisenberger A and Bloch MH: Meta-analysis of LCPUFA supplementation of infant formula and visual acuity. Pediatrics. 2013 Jan;131 (1) :e262-72. Epub 2012 Dec 17. PMID: 23248232

Bloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G and Pittenger C: Effects of ketamine in treatment-refractory obsessive-compulsive disorder. Biol Psychiatry. 2012 Dec 1;72 (11) :964-70. Epub 2012 Jul 10. PMID: 22784486


Anticevic A, Gancsos M, Murray JD, Repovs G, Driesen NR, Ennis DJ, Niciu MJ, Morgan PT, Surti TS, Bloch MH, Ramani R, Smith MA, Wang XJ, Krystal JH and Corlett PR: NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia. Proc Natl Acad Sci U S A. 2012 Oct 9;109 (41) :16720-5. Epub 2012 Sep 25. PMID: 23012427


Middei S, Spalloni A, Longone P, Pittenger C, O'Mara SM, Marie H and Ammassari-Teule M: CREB selectively controls learning-induced structural remodeling of neurons. Learn Mem. 2012 Jul 18;19 (8) :330-6. Epub 2012 Jul 18. PMID: 22815537


Bloch MH: Misplaced Fear? FDA Contraindication to Psychostimulant Use in Children with Tics. Evid Based Child Health. 2012 Jul;7 (4) :1231-1234. PMID: 25152702


Gray SM and Bloch MH: Systematic review of proinflammatory cytokines in obsessive-compulsive disorder. Curr Psychiatry Rep. 2012 Jun;14 (3) :220-8. PMID: 22477442


Qawasmi A, Landeros-Weisenberger A, Leckman JF and Bloch MH: Meta-analysis of long-chain polyunsaturated fatty acid supplementation of formula and infant cognition. Pediatrics. 2012 Jun;129 (6) :1141-9. Epub 2012 May 28. PMID: 22641753


Carrasco M, Volkmar FR and Bloch MH: Pharmacologic treatment of repetitive behaviors in autism spectrum disorders: evidence of publication bias. Pediatrics. 2012 May;129 (5) :e1301-10. Epub 2012 Apr 23. PMID: 22529279


Bontempo A, Panza KE and Bloch MH: D-cycloserine augmentation of behavioral therapy for the treatment of anxiety disorders: a meta-analysis. J Clin Psychiatry. 2012 Apr;73 (4) :533-7. PMID: 22579153


Lebowitz ER, Panza KE, Su J and Bloch MH: Family accommodation in obsessive-compulsive disorder. Expert Rev Neurother. 2012 Feb;12 (2) :229-38. PMID: 22288678


Hampson M, Stoica T, Saksa J, Scheinost D, Qiu M, Bhawnani J, Pittenger C, Papademetris X and Constable T: Real-time fMRI biofeedback targeting the orbitofrontal cortex for contamination anxiety. J Vis Exp. 2012 Jan 20; (59) Epub 2012 Jan 20. PMID: 22297729


Chalita PJ, Palacios L, Cortes JF, Landeros-Weisenberger A, Panza KE and Bloch MH: Relationship of dropout and psychopathology in a high school sample in Mexico. Front Psychiatry. 2012;3 :20. Epub 2012 Mar 13. PMID: 22419912

Pittenger C: Pathophysiological modeling of obsessive-compulsive disorder: challenges, and progress. Biol Psychiatry. 2011 Dec 1;70 (11) :1002-3. PMID: 22045035


Pittenger C, Bloch MH and Williams K: Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment. Pharmacol Ther. 2011 Dec;132 (3) :314-32. Epub 2011 Sep 22. PMID: 21963369


Bloch MH and Qawasmi A: Omega-3 fatty acid supplementation for the treatment of children with attention-deficit/hyperactivity disorder symptomatology: systematic review and meta-analysis. J Am Acad Child Adolesc Psychiatry. 2011 Oct;50 (10) :991-1000. Epub 2011 Aug 12. PMID: 21961774


Bloch MH, Sukhodolsky DG, Dombrowski PA, Panza KE, Craiglow BG, Landeros-Weisenberger A, Leckman JF, Peterson BS and Schultz RT: Poor fine-motor and visuospatial skills predict persistence of pediatric-onset obsessive-compulsive disorder into adulthood. J Child Psychol Psychiatry. 2011 Sep;52 (9) :974-83. Epub 2011 Jan 19. PMID: 21244423


Jakubovski E, Pittenger C, Torres AR, Fontenelle LF, do Rosario MC, Ferrão YA, de Mathis MA, Miguel EC and Bloch MH: Dimensional correlates of poor insight in obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15;35 (7) :1677-81. Epub 2011 May 27. PMID: 21640153


Kelmendi B, Holsbach-Beltrame M, McIntosh AM, Hilt L, George ED, Kitchen RR, Carlyle BC, Pittenger C, Coric V, Nolen-Hoeksema S, Sanacora G and Simen AA: Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder. Neurosci Lett. 2011 Jun 8;496 (3) :195-9. Epub 2011 Apr 20. PMID: 21529705


Pittenger C: Epigenetic modification of the BDNF locus by early-life enrichment: towards a molecular correlate of resilience? Neurosci Lett. 2011 May 20;495 (3) :165-7. Epub 2011 Mar 22. PMID: 21435373


Krusong K, Ercan-Sencicek AG, Xu M, Ohtsu H, Anderson GM, State MW and Pittenger C: High levels of histidine decarboxylase in the striatum of mice and rats. Neurosci Lett. 2011 May 16;495 (2) :110-4. Epub 2011 Apr 1. PMID: 21440039


Bloch M, State M and Pittenger C: Recent advances in Tourette syndrome. Curr Opin Neurol. 2011 Apr;24 (2) :119-25. PMID: 21386676


Palermo SD, Bloch MH, Craiglow B, Landeros-Weisenberger A, Dombrowski PA, Panza K, Smith ME, Peterson BS and Leckman JF: Predictors of early adulthood quality of life in children with obsessive-compulsive disorder. Soc Psychiatry Psychiatr Epidemiol. 2011 Apr;46 (4) :291-7. Epub 2010 Feb 27. PMID: 20191262


Reyes MM, Panza KE, Martin A and Bloch MH: Time-lag bias in trials of pediatric antidepressants: a systematic review and meta-analysis. J Am Acad Child Adolesc Psychiatry. 2011 Jan;50 (1) :63-72. Epub 2010 Nov 25. PMID: 21156271

Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC and Lombroso PJ: Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A. 2010 Nov 2;107 (44) :19014-9. Epub 2010 Oct 18. PMID: 20956308


Gourley SL, Lee AS, Howell JL, Pittenger C and Taylor JR: Dissociable regulation of instrumental action within mouse prefrontal cortex. Eur J Neurosci. 2010 Nov;32 (10) :1726-34. Epub 2010 Oct 12. PMID: 21044173


Baldan Ramsey LC and Pittenger C: Cued and spatial learning in the water maze: equivalent learning in male and female mice. Neurosci Lett. 2010 Oct 11;483 (2) :148-51. Epub 2010 Aug 5. PMID: 20691760


Leckman JF, Bloch MH, Smith ME, Larabi D and Hampson M: Neurobiological substrates of Tourette's disorder. J Child Adolesc Psychopharmacol. 2010 Aug;20 (4) :237-47. PMID: 20807062


Bloch MH and Pittenger C: The Genetics of Obsessive-Compulsive Disorder. Curr Psychiatry Rev. 2010 May 1;6 (2) :91-103. PMID: 23970845


Landeros-Weisenberger A, Bloch MH, Kelmendi B, Wegner R, Nudel J, Dombrowski P, Pittenger C, Krystal JH, Goodman WK, Leckman JF and Coric V: Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder. J Affect Disord. 2010 Feb;121 (1-2) :175-9. Epub 2009 Jul 3. PMID: 19577308

Bloch MH and Leckman JF: Clinical course of Tourette syndrome. J Psychosom Res. 2009 Dec;67 (6) :497-501. PMID: 19913654


Bloch MH, Craiglow BG, Landeros-Weisenberger A, Dombrowski PA, Panza KE, Peterson BS and Leckman JF: Predictors of early adult outcomes in pediatric-onset obsessive-compulsive disorder. Pediatrics. 2009 Oct;124 (4) :1085-93. Epub 2009 Sep 28. PMID: 19786445


Bloch MH: Trichotillomania across the life span. J Am Acad Child Adolesc Psychiatry. 2009 Sep;48 (9) :879-83. PMID: 19692854


Bloch MH, Panza KE, Landeros-Weisenberger A and Leckman JF: Meta-analysis: treatment of attention-deficit/hyperactivity disorder in children with comorbid tic disorders. J Am Acad Child Adolesc Psychiatry. 2009 Sep;48 (9) :884-93. PMID: 19625978


Leckman JF, Bloch MH and King RA: Symptom dimensions and subtypes of obsessive-compulsive disorder: a developmental perspective. Dialogues Clin Neurosci. 2009;11 (1) :21-33. PMID: 19432385


Fasano S, Pittenger C and Brambilla R: Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse. Front Behav Neurosci. 2009;3 :29. Epub 2009 Sep 9. PMID: 19826621

Bloch MH, Landeros-Weisenberger A, Rosario MC, Pittenger C and Leckman JF: Meta-analysis of the symptom structure of obsessive-compulsive disorder. Am J Psychiatry. 2008 Dec;165 (12) :1532-42. Epub 2008 Oct 15. PMID: 18923068


Lee AS, Duman RS and Pittenger C: A double dissociation revealing bidirectional competition between striatum and hippocampus during learning. Proc Natl Acad Sci U S A. 2008 Nov 4;105 (44) :17163-8. Epub 2008 Oct 27. PMID: 18955704


Leckman JF and Bloch MH: A developmental and evolutionary perspective on obsessive-compulsive disorder: whence and whither compulsive hoarding? Am J Psychiatry. 2008 Oct;165 (10) :1229-33. PMID: 18829875


Bloch MH, Landeros-Weisenberger A, Sen S, Dombrowski P, Kelmendi B, Coric V, Pittenger C and Leckman JF: Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: systematic review. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B (6) :850-8. PMID: 18186076


Bloch MH: Emerging treatments for Tourette's disorder. Curr Psychiatry Rep. 2008 Aug;10 (4) :323-30. PMID: 18627671


Pittenger C, Kelmendi B, Wasylink S, Bloch MH and Coric V: Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a series of 13 cases, with long-term follow-up. J Clin Psychopharmacol. 2008 Jun;28 (3) :363-7. PMID: 18480706


Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS and Flavell RA: Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nat Med. 2008 Jun;14 (6) :681-7. Epub 2008 Jun 1. PMID: 18516051


Pittenger C, Coric V, Banasr M, Bloch M, Krystal JH and Sanacora G: Riluzole in the treatment of mood and anxiety disorders. CNS Drugs. 2008;22 (9) :761-86. PMID: 18698875


Pittenger C and Duman RS: Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology. 2008 Jan;33 (1) :88-109. Epub 2007 Sep 12. PMID: 17851537

Bloch MH, Landeros-Weisenberger A, Dombrowski P, Kelmendi B, Wegner R, Nudel J, Pittenger C, Leckman JF and Coric V: Systematic review: pharmacological and behavioral treatment for trichotillomania. Biol Psychiatry. 2007 Oct 15;62 (8) :839-46. Epub 2007 Aug 28. PMID: 17727824


Pittenger C, Sanacora G and Krystal JH: The NMDA receptor as a therapeutic target in major depressive disorder. CNS Neurol Disord Drug Targets. 2007 Apr;6 (2) :101-15. PMID: 17430148


Pittenger C and Desan PH: Gabapentin abuse, and delirium tremens upon gabapentin withdrawal. J Clin Psychiatry. 2007 Mar;68 (3) :483-4. PMID: 17388722


Coric V, Kelmendi B, Pittenger C, Wasylink S, Bloch MH and Green J: Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania. J Clin Psychiatry. 2007 Jan;68 (1) :170-1. PMID: 17284151

Sasso DA, Kalanithi PS, Trueblood KV, Pittenger C, Kelmendi B, Wayslink S, Malison RT, Krystal JH and Coric V: Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors. J Clin Psychopharmacol. 2006 Dec;26 (6) :685-7. PMID: 17110840


Leckman JF, Bloch MH, Scahill L and King RA: Tourette syndrome: the self under siege. J Child Neurol. 2006 Aug;21 (8) :642-9. PMID: 16970864


Bloch MH, Sukhodolsky DG, Leckman JF and Schultz RT: Fine-motor skill deficits in childhood predict adulthood tic severity and global psychosocial functioning in Tourette's syndrome. J Child Psychol Psychiatry. 2006 Jun;47 (6) :551-9. PMID: 16712631


Pittenger C, Naungayan C, Kendell SF, Coric V, Malison R, Krystal JH and Sanacora GS: Visual hallucinations from the addition of riluzole to memantine and bupropion. J Clin Psychopharmacol. 2006 Apr;26 (2) :218-20. PMID: 16633160


Pittenger C, Fasano S, Mazzocchi-Jones D, Dunnett SB, Kandel ER and Brambilla R: Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. J Neurosci. 2006 Mar 8;26 (10) :2808-13. PMID: 16525060


Leckman JF, Bloch MH, King RA and Scahill L: Phenomenology of tics and natural history of tic disorders. Adv Neurol. 2006;99 :1-16. PMID: 16536348


Bloch MH, Peterson BS, Scahill L, Otka J, Katsovich L, Zhang H and Leckman JF: Adulthood outcome of tic and obsessive-compulsive symptom severity in children with Tourette syndrome. Arch Pediatr Adolesc Med. 2006 Jan;160 (1) :65-9. PMID: 16389213


Pittenger C, Krystal JH and Coric V: Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. NeuroRx. 2006 Jan;3 (1) :69-81. PMID: 16490414


Lafleur DL, Pittenger C, Kelmendi B, Gardner T, Wasylink S, Malison RT, Sanacora G, Krystal JH and Coric V: N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder. Psychopharmacology (Berl). 2006 Jan;184 (2) :254-6. Epub 2005 Dec 22. PMID: 16374600

Pittenger C, Krystal JH and Coric V: Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder. J Clin Psychiatry. 2005 Nov;66 (11) :1492-3. PMID: 16420092


Pittenger C, Kelmendi B, Bloch M, Krystal JH and Coric V: Clinical treatment of obsessive compulsive disorder. Psychiatry (Edgmont). 2005 Nov;2 (11) :34-43. PMID: 21120095


Bloch MH, Leckman JF, Zhu H and Peterson BS: Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome. Neurology. 2005 Oct 25;65 (8) :1253-8. PMID: 16247053


Coric V, Taskiran S, Pittenger C, Wasylink S, Mathalon DH, Valentine G, Saksa J, Wu YT, Gueorguieva R, Sanacora G, Malison RT and Krystal JH: Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. Biol Psychiatry. 2005 Sep 1;58 (5) :424-8. PMID: 15993857


Etkin A, Pittenger C, Polan HJ and Kandel ER: Toward a neurobiology of psychotherapy: basic science and clinical applications. J Neuropsychiatry Clin Neurosci. 2005 Spring;17 (2) :145-58. PMID: 15939967

Bloch MH, Hwang WC, Baehring JM and Chambers SK: Paraneoplastic limbic encephalitis: ovarian cancer presenting as an amnesic syndrome. Obstet Gynecol. 2004 Nov;104 (5 Pt 2) :1174-7. PMID: 15516442


Huang YY, Pittenger C and Kandel ER: A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing. Proc Natl Acad Sci U S A. 2004 Jan 20;101 (3) :859-64. Epub 2004 Jan 7. PMID: 14711997

Pittenger C and Kandel ER: In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus. Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29;358 (1432) :757-63. PMID: 12740123


Kandel ER and Pittenger C: [Past and future studies of memory]. Kos. 2003 Apr; (211) :38-43. PMID: 12760381


Barco A, Pittenger C and Kandel ER: CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects. Expert Opin Ther Targets. 2003 Feb;7 (1) :101-14. PMID: 12556206

Pittenger C, Huang YY, Paletzki RF, Bourtchouladze R, Scanlin H, Vronskaya S and Kandel ER: Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory. Neuron. 2002 Apr 25;34 (3) :447-62. PMID: 11988175