C&MP 550a: Physiological Systems

Course Listings

• Cellular and Molecular Physiology: C&MP 550a
• Biomedical Engineering: BENG 350a
• Engineering and Applied Science: ENAS 550a
• Molecular and Cellular Developmental Biology: MCDB 310a/550a

Course Information

Web site for course information: https://classesv2.yale.edu/portal/ 
Weekly quiz website:  http://courseinfo.med.yale.edu

Classes:   MWF 9:25-10:15 am
Location:211 Mason Laboratory
Format:36 Lectures, weekly quizzes, two midterm examinations, final examination.
Discussion Sections:Students will be assigned to one discussion section M 7-8pm; M 8-9pm; T 7-8pm; or T 8-9pm.

Additional weekly meeting for graduate students:

Wednesdays with Instructor in SHM B-145 at 5 to 6pm.

Instructors 

Lead Instructor: Mark Saltzman, Ph.D.

Graduate Student Conference Leader:Emile Boulpaep, M.D.

Teaching Fellows & Discussion Section Leaders:
TBA

Course Description

The course develops a foundation in human physiology by examining the homeostasis of vital parameters within the body, and the biophysical properties of cells, tissues, and organs. Basic concepts in cell and membrane physiology are synthesized through exploring the function of skeletal, smooth, and cardiac muscle. The physical basis of blood flow, mechanisms of vascular exchange cardiac performance and regulation of overall circulatory function are discussed. Respiratory physiology explores the mechanics of ventilation, gas diffusion, and acid-base balance. Renal physiology examines the formation and composition of urine and the regulation of electrolyte, fluid, and acid-base balance. Organs of the digestive system are discussed from the perspective of substrate metabolism and energy balance. Hormonal regulation is applied to metabolic control and to calcium, water, and electrolyte balance. The biology of nerve cells is addressed with emphasis on synaptic transmission and simple neuronal circuits within the central nervous system. The special senses are considered in the framework of sensory transduction. Weekly discussion sections provide a forum for in-depth exploration of topics. Graduate students evaluate research findings through literature review and weekly meetings with the instructor.

Nature and amount of work required

Text (BENG 350a, MCDB 310a): Berne and Levy "Physiology", Koeppen and Stanton , 2008 6th edition

Text (ENAS 550a, MCDB 550a, CMP 550a):Textbook of Medical Physiology (2002) by Walter Boron and Emile Boulpaep, W.B. Saunders Company

Number of pages of reading per week: ~ 50 to 70; indicated for each lecture.
Quizzes and Discussion Sections: (20% of grade)
Midterm: Two midterms (each 20% of grade).
End of term: Final examination (40% of grade).
Examination format: multiple choice, true-false, & short answer.
Graduate students: weekly meeting and report (20% of grade).

Fall 2008 Schedule