Recent Pharmacology Theses

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Here is a list of students who have recently defended their Ph.D. Thesis in Pharmacology, along with a brief description of their thesis work.

2/24/15 Oriana Fisher - Structural studies of Cerebral Cavernous Malformations 2 (CCM2) reveal the basis for its interactions with protein binding

2/18/13 Catherine Chen - Functional re-engineering of protein kinase specificity

10/30/12 Nilda Alicea Velazquez - Guided studies of SHP-1 phosphatase substrate recognition

6/15/12 Michelle Mo - The role of NCS-1 in chemotherapy-induced peripheral neuropathy

8/23/11 Fatih Mercan - SHP-2 is Required for Nutrient-Mediated Calcium Activation of S6 Kinase 1

3/26/11 Yao Cheng - Mechanistic Studies of the Anti-Hepatitis C Activity of a Novel Class of Tetraphenylporphyrins

1/28/11 Alicia Koblansky - Characterization of a novel Toll-like Receptor, TLR12, in the host-pathogen immunse response to Apicomplexan parasites

10/21/10 Genevieve Ko - Probing the physiological function of epsin isoforms

9/2/10 Jasmine Escalera – Role of TRPA1 in Cutaneous Irritant Sensing and Contact Dermatitis

8/13/10 Mayra Garcia - Regulation of Hepatitis B Virus Replication by the Ubiquitin-Proteasome Pathway

3/2/10 Jiae Kim - Determining the Role of Viral and Cellular Proteins in Human Immunodeficiency Virus Type-1 Replication

1/15/10 David Harburger - Structure/function analysis of the kindlin family proteins.

11/3/09 Paulette Wright - The role of Nogo-B in asthma pathogenesis: An airway epithelial inhibitor of allergic inflammation

9/28/09 Kenneth Harrison - Characterization of the Nogo-B receptor: Identification of a nexus between intracellular cholesterol trafficking and cis-prenyltransferase activity.

9/24/09 Robert Carrillo - Electrical activity regulates developmental plassticity at the Drosphila neuromuscular junction.

9/18/09 Erika Andrade - Mechanisms of Neuroplasticity in Drug Addiction: Regulation of serine/threonine phosphatases and their roles in the striatum.

9/10/09 Jan Pawlicki - Molecular mechanisms underlying efficient and regulated microRNA production.

3/5/09 Chris Bailey - Mechanistic Insight into the Design of Novel Bifunctional Inhibitors of HIV-1 Reverse Trasnscriptase.

3/10/09 Maya Davis - The Calcineurin Connection: Regulator of Calmodulin Signaling (RCS) and Nuclear Factor of Activated T-cells (NFAT) in Rodent Striatum.

3/13/09 Rachel Roth - Regulation of Metabolic Homeostatis by the MAP Kinase Phosphatase-1.

9/29/08 Michael Sivula - TRPA1 is a Peripheral Neuronal Sensor for Oxidants and Lipid Peroxidation Products.