Emanuela Marina Bruscia PhD

Assistant Professor of Pediatrics (Respiratory)

Departments & Organizations

Office of Student ResearchPediatrics: Pediatric Respiratory Medicine

Research Interests

Cystic Fibrosis; Lung inflammation; Macrophages more...


  • Ph.D., Tor Vergata University in Rome, 2002

Selected Publications

  • Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation. Zhang PX, Cheng J, Zou S, D'Souza AD, Koff JL, Lu J, Lee PJ,n Krause DS, Egan ME, Bruscia EM. Nat Commun. 2015 Feb 10;6:6221.
  • Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator. Zhang PX, Murray TS, Villella VR, Ferrari E, Esposito S, D'Souza A, Raia V, Maiuri L, Krause DS, Egan ME, Bruscia EM. J Immunol. 2013 May 15;190(10):5196-206.
  • Innate immunity in cystic fibrosis lung disease (Review). Hartl D, Gaggar A, Bruscia EM, Hector A, Marcos V, Jung A, Greene C, McElvaney G, Mall M, Döring G. J Cyst Fibros. 2012 Sep;11(5):363-82.



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