Pathogenesis of Youth and Type 2 Diabetes and Prediabetes

What is the purpose of this trial?

The goal is to explore if genetic factors are associated with insulin resistance in children and and adolescents. Screening includes having an oral glucose tolerance test to measure blood glucose levels and insulin levels and to have a blood sample drawn for genetic testing. Individuals with the CC or TT genotype of the TCF7L2 gene and are have impaired glucose tolerance based on the oral glucose tolerance test are eligible to participate in the main study which includes an infusion study and other tests of glucose and insulin secretion.


Participation Guidelines

Ages: 12 - 18 years

Gender: Both


National Institute of Diabetes and Digestive & Kidney Diseases

Dates: 02/22/2017 - 10/01/2022

Last Updated: 04/04/2017

Study HIC#: 2000020183

Get Involved

For more information about this study, contact:
Bridget M. Pierpont
203-785-2942
bridget.pierpont@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

Trial Image

Investigators

Sonia Caprio

Principal Investigator

Sub-Investigators