Anxiety Disorders; Child Psychiatry; Genetics; Genetics, Behavioral; Tourette Syndrome; Psychiatry; Tic Disorders
Uncovering the genetic and epigenetic basis of childhood neuropsychiatric disorders including Tourette Syndrome, OCD, anxiety, and autism spectrum disorders. Using these findings to understand the biology of disorders, improve diagnosis and treatment.
Extensive Research Description
- Genetic sequence and structural variation in Tourette syndrome, Complex Motor Stereotypies, and Obsessive-Compulsive Disorder
- Clinical trials of medications for children with tic disorders
- Fernandez TV, King RA, Pittenger C (2015). Tourette syndrome and translational clinical science. Journal of the American Academy of Child & Adolescent Psychiatry 54 (1):6-8.
- Lennington J, et al. (2014). Transcriptome analysis of the human striatum in Tourette syndrome. Biological Psychiatry. Jul 24 Epub ahead of print.
- Fernandez TV, et al. (2012). Rare copy number variants in Tourette syndrome disrupt genes in histaminergic pathways and overlap with autism. Biological Psychiatry 71 (5):392-402.
- Scharf JM, et al. (2012). Genome-wide association study of Tourette syndrome. Molecular Psychiatry. Aug 14 [Epub].
- Sanders SJ et al. (2011). Multiple recurrent de novo copy number variations (CNVs), including duplications of the 7q11.23 Williams-Buren syndrome region, are strongly associated with autism. Neuron 70 (5):863-885.
- Ercan-Sencicek AG, et al. (2010). L-histidine decarboxylase and Tourette’s syndrome. New England Journal of Medicine 362: 1901-8.