Nicola Santoro MD, PhD

Associate Research Scientist in Pediatrics (Endocrinology)

Research Interests

Childhood obesity, hepatic steatosis, dyslipidemia.


Research Summary

Genetics of obesity, type 2 diabetes, hepatic steatosis, dyslipidemia in obese youths


Selected Publications

  • Tuomi T, Santoro N, Caprio S, Cai M, Weng J, Groop L. The many faces of diabetes: a disease with increasing heterogeneity. Lancet in press
  • Giannini C, Dalla Man C, Groop L, Cobelli C, Zhao H, Shaw MM, Duran E, Pierpont B, Bale AE, Caprio S, Santoro N. The co-occurrence of risk alleles in or near genes modulating insulin secretion predisposes obese youth to prediabetes. Diabetes Care 2013 In press
  • Santoro N, Feldstein AE, Enoksson E, Pierpont B, Kursawe R, Kim G, Caprio S. The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance and common gene variants. Diabetes Care 2013; 36: 1353-60.
  • Santoro N, Zhang CK, Zhao H, Pakstis AJ, Kim G, Kursawe R, Dykas DJ, Bale AE, Giannini C, Pierpont B, Shaw MM, Groop L, Caprio S. A Variant in the Glucokinase Regulatory Protein (GCKR) Gene is Associated with Fatty Liver in Obese Children and Adolescents. Hepatology 2012; 55:781-789
  • Santoro N, Kursawe R, D’Adamo E, Dykas DJ, Zhang CK, Bale AE, Cali’ A, Narayan D,Shaw MM, Pierpont B, Savoye M, Lartaud D, Eldrich S, Cushman SW, Zhao H, Shulman GI, Caprio S. A Common Variant in the Patatin-Like Phopholipase 3 Gene (PNPLA3) is Associated with Fatty Liver Disease in Obese Children and Adolescents. Hepatology 2010; 52: 1281-90.

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