Research

The Pediatric Neurology Team at Yale University and Yale-New Haven Hospital is involved in a wide spectrum of Clinical and Basic Science Research. Our research seeks to improve the lives of children with neurological problems by understanding the mechanisms of disease and developing new therapies. Research interests include:

  • Bioethics: applying principles of beneficence, autonomy, respect for persons and justice as applied to neurological disease and care of neurological patients (Dr. Miller)
  • Connectivity: Alterations in functional organization of the developing brain: Resting state functional connectivity studies of extremely preterm neonates and gestational-age matched typically developing babies (Dr. Ment)
  • Development: Mechanisms of developmental regression in autism and epilepsy (Dr. McVicar)
  • Dyslexia: Longitudinal studies of dyslexia, including functional imaging, outcome and treatment strategies (Drs. B Shaywitz and S Shaywitz)
  • Epilepsy: Pediatric epilepsy and the mechanisms of early infantile epileptogenic encephalopathy (Dr. Knight)
  • Habit formation: Synaptic plasticity in models of substance dependence (Dr. Bamford)
  • Movement and paroxysmal disorders: Mechanisms of L-Dopa induced dyskinesias in Parkinsonism, Synaptic plasticity in Parkinson’s disease and Huntington’s disease (Dr. Bamford)
  • Multiple sclerosis and pediatric white matter disorders: Demyelinating disease and risk of further multiple sclerosis following a radiological isolated event (Dr. Makhani)
  • Neuromuscular disease: Mechanisms underlying neuromuscular disease in children (Dr. Ionita)

For more information about the research of our faculty, view their faculty profiles: