Sonia Caprio MD

Professor of Pediatrics (Endocrinology)

Research Interests

Pathophysiology of Insulin Resistance in Children; Metabolic Complications of Childhood Obesity; Pathophysiology of Prediabetes in Obese Youth


Research Summary

Dr. Sonia Caprio researches the pathophysiology of metabolic defects of juvenile obesity, including metabolic predictors and markers of childhood obesity. Her research includes the pathophysiology of Type 2 Diabetes in youth, including uncovering the metabolic phenotype of pre-diabetes in youth. She is the Principle Investigator of an NIH-funded multicenter study of the treatment of T2DM in youth.


Selected Publications

  • A low disposition index in adolescent offspring of mothers with gestational diabetes: a risk marker for the development of impaired glucose tolerance in youth. Holder T, Giannini C, Santoro N, Pierpont B, Shaw M, Duran E, Caprio S, Weiss R. Diabetologia. 2014 Nov;57(11):2413-20. doi: 10.1007/s00125-014-3345-2. Epub 2014
  • The development of type 2 diabetes in the obese adolescents: a growing challenge. Caprio S. Clin Biochem. 2014 Jun;47(9):721. doi: 10.1016/j.clinbiochem.2014.05.027. Epub 2014 May 20
  • Leptin Is Associated With Exaggerated Brain Reward and Emotion Responses to Food Images in Adolescent Obesity. Jastreboff AM, Lacadie C, Seo D, Kubat J, Van Name MA, Giannini C, Savoye M, Constable RT, Sherwin RS, Caprio S, Sinha R. Diabetes Care. 2014 Aug 19. pii: DC_140525.

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