Ania Magdalena Jastreboff MD, PhD

Assistant Professor of Medicine (Endocrinology) and of Pediatrics (Endocrinology); Assistant Professor of Pediatrics (Pediatric Endocrinology)

Research Interests

Obesity; Insulin resistance; Type 2 diabetes; Neural control of eating behaviors; Weight-loss maintenance; Dietary glycemic index, Diabetes technology tools, Transitions of care from pediatric to adult care

Research Summary

Dr. Jastreboff’s research seeks to elucidate neural mechanisms involved in obesity including neural control of eating behaviors. During her doctoral thesis work, Dr. Jastreboff became interested in understanding how metabolic perturbations, such as insulin resistance, hyperinsulinemia, leptin resistance, etc, affect neural mechanisms, which subsequently impact eating behavior and weight gain. To this end, she utilizes functional MRI to examine neural responses in obese adults and adolescents (insulin resistant and insulin sensitive) to various food cues (viewing images of high-calorie and low-calorie foods, ingestion of glucose or fructose drinks, etc). Dr. Jastreboff’s overarching goal is to conduct research that is clinically applicable for the treatment of obesity and has a clear public health impact to mitigate the obesity pandemic.

Selected Publications

  • Sherwin R, Jastreboff AM. Year in Diabetes 2012: The Diabetes Tsunami. J Clin Endocrinol Metab. 2012 Nov 26. [Epub ahead of print] (PMID: 23185035)
  • Jastreboff AM, Sinha R, Lacadie C, Small D, Sherwin RS, Potenza MN. Neural Correlates of Stress- and Food- Cue–Induced Food Craving In Obesity: Association with insulin levels. Diabetes Care 2012 October 15 [Epub ahead of print] (PMID: 23069840)
  • Hairston KG, Ducharme JL, Treuth MS, Hsueh WC, Jastreboff AM, Ryan KA, Shi X, Mitchell BD, Shuldiner AR, Snitker S. Comparison of BMI and Physical Activity Between Old Order Amish Children and Non-Amish Children. Diabetes Care 2012 Oct 23 [Epub ahead of print] (PMID: 23093661)
  • Phipps MS, Jastreboff AM, Furie K, Kernan WN. The diagnosis and management of cerebrovascular disease in diabetes. Curr Diab Rep 2012 Jun; 12(3):314-23. (PMID 22492061)
  • Jastreboff AM, Potenza MN, Lacadie C, Hong K, Sherwin RS, Sinha R. Body Mass Index, metabolic factors, and striatal activation during stressful and neutral-relaxing states: an fMRI study. Neuropsychopharmacology. January 2011; 36: 627-637. (PMID: 21048702)
  • Jastreboff A & Sherr J. Three faces of hypothalamic tumors. Journal of Pediatric Endocrinology & Metabolism. 2007 April; 20(4): 471. (PMID: 17550209)
  • Jastreboff AM, Cymet TC (2002). Role of the human papilloma virus in the development of cervical intraepithelial neoplasia and malignancy. Postgraduate Medical Journal 78: 225-228. (PMCID: PMC1742321)

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