Edward Vincent S. Faustino MD
Assistant Professor of Pediatrics (Critical Care)
Glucose control in critically ill children; Prevention of deep venous thrombosis; Sedation in children with respiratory failure; Improving quality of care and safety in the PICU
Current Projects1. Epidemiology of Central Venous Line-Related Deep Venous Thrombosis in Critically Ill Children. The goal of this study is to determine the incidence and outcomes of central venous line-related deep venous thrombosis in critically ill children.
2. Sedation Management in Pediatric Patients with Acute Respiratory Failure. The goal of this study is to test an innovative approach to sedation management of children with acute respiratory failure.
3. Genetic Variations and Biomarkers in Children with Acute Lung Injury. The goal of this study is to test the prediction that genetic variations in selected candidate genes and selected plasma biomarkers related to inflammation, coagulation, and/or surfactant are associated with the development of acute lung injury in children with parenchymal lung disease.
4. Prevention of Ventilator-Associated Pneumonia in Critically Ill Children. The goal of this project is to determine the incidence of ventilator-associated pneumonia in critically ill children and to develop a bundle to minimize its occurrence.
5. A Pilot Randomized Controlled Trial of Strict Blood Glucose Control utilizing eProtocol-Insulin in Pediatric ICUs. The objective of this study is to determine the feasibility of randomizing hyperglycemic critically ill children to either strict or liberal blood glucose control.
Dr. Faustino is involved in improving the outcomes and care of critically ill children. He is working on the prevention of the development of blood clots in this patient population. He is also involved in studies to improve the sedation of patients requiring mechanical assistance to breathe, to prevent the occurrence of lung infections in these patients and to improve survival by controlling blood sugar.
Extensive Research Description
Dr. Faustino is involved in patient-oriented clinical research and performance improvement. His primary research interest is the prevention of deep vein thrombosis in critically ill children. He has ongoing projects (1) to determine the population of critically ill children that will benefit the most from pharmacologic prophylaxis against deep vein thromobosis, and (2) to identify the optimal outcome measure for trials on prevention of deep vein thrombosis. He is also investigating glucose control in critically ill children, sedation in mechanically ventilated patients and ventilator-associated pneumonia.