YPTS Publications

Carvajal-Hausdorf DE, Schalper KA, Pusztai L, Psyrri A, Kalogeras KT, Kotoula V, Fountzilas G and Rimm DL: Measurement of Domain-Specific HER2 (ERBB2) Expression May Classify Benefit From Trastuzumab in Breast Cancer. J Natl Cancer Inst. 2015 Aug;107 (8) Epub 2015 May 19. PMID: 25991002

Jilaveanu LB, Parisi F, Barr ML, Zito CR, Cruz-Munoz W, Kerbel RS, Rimm DL, Bosenberg MW, Halaban R, Kluger Y and Kluger HM: PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis. Clin Cancer Res. 2015 May 1;21 (9) :2138-47. Epub 2014 Oct 14. PMID: 25316811

Kunstman JW, Juhlin CC, Goh G, Brown TC, Stenman A, Healy JM, Rubinstein JC, Choi M, Kiss N, Nelson-Williams C, Mane S, Rimm DL, Prasad ML, Höög A, Zedenius J, Larsson C, Korah R, Lifton RP and Carling T: Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing. Hum Mol Genet. 2015 Apr 15;24 (8) :2318-29. Epub 2015 Jan 9. PMID: 25576899

Wimberly H, Brown JR, Schalper K, Haack H, Silver MR, Nixon C, Bossuyt V, Pusztai L, Lannin DR and Rimm DL: PD-L1 Expression Correlates with Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer. Cancer Immunol Res. 2015 Apr;3 (4) :326-32. Epub 2014 Dec 19. PMID: 25527356

Carvajal-Hausdorf DE, Schalper KA, Neumeister VM and Rimm DL: Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic. Lab Invest. 2015 Apr;95 (4) :385-96. Epub 2014 Dec 15. PMID: 25502176

Kluger HM, Zito CR, Barr ML, Baine MK, Chiang VL, Sznol M, Rimm DL, Chen L and Jilaveanu LB: Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites. Clin Cancer Res. 2015 Mar 18; Epub 2015 Mar 18. PMID: 25788491

Davidson NE and Rimm DL: Expertise vs evidence in assessment of breast biopsies: an atypical science. JAMA. 2015 Mar 17;313 (11) :1109-10. PMID: 25781438

Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, Osterman AL, Kluger Y and Ronai ZA: Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 2015 Mar 9;27 (3) :354-69. PMID: 25759021

Blume-Jensen P, Berman DM, Rimm DL, Shipitsin M, Putzi M, Nifong TP, Small C, Choudhury S, Capela T, Coupal L, Ernst C, Hurley A, Kaprelyants A, Chang H, Giladi E, Nardone J, Dunyak J, Loda M, Klein EA, Magi-Galluzzi C, Latour M, Epstein JI, Kantoff P and Saad F: Development and Clinical Validation of an In Situ Biopsy-Based Multimarker Assay for Risk Stratification in Prostate Cancer. Clin Cancer Res. 2015 Mar 2; Epub 2015 Mar 2. PMID: 25733599

Juhlin CC, Goh G, Healy JM, Fonseca AL, Scholl UI, Stenman A, Kunstman JW, Brown TC, Overton JD, Mane SM, Nelson-Williams C, Bäckdahl M, Suttorp AC, Haase M, Choi M, Schlessinger J, Rimm DL, Höög A, Prasad ML, Korah R, Larsson C, Lifton RP and Carling T: Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma. J Clin Endocrinol Metab. 2015 Mar;100 (3) :E493-502. Epub 2014 Dec 9. PMID: 25490274

Vassilakopoulou M, Parisi F, Siddiqui S, England AM, Zarella ER, Anagnostou V, Kluger Y, Hicks DG, Rimm DL and Neumeister VM: Preanalytical variables and phosphoepitope expression in FFPE tissue: quantitative epitope assessment after variable cold ischemic time. Lab Invest. 2015 Mar;95 (3) :334-41. Epub 2014 Nov 24. PMID: 25418580

Schalper KA, Brown J, Carvajal-Hausdorf D, McLaughlin J, Velcheti V, Syrigos KN, Herbst RS and Rimm DL: Objective measurement and clinical significance of TILs in non-small cell lung cancer. J Natl Cancer Inst. 2015 Mar;107 (3) Epub 2015 Feb 3. PMID: 25650315

Salgado R, Denkert C, Demaria S, Sirtaine N, Klauschen F, Pruneri G, Wienert S, Van den Eynden G, Baehner FL, Penault-Llorca F, Perez EA, Thompson EA, Symmans WF, Richardson AL, Brock J, Criscitiello C, Bailey H, Ignatiadis M, Floris G, Sparano J, Kos Z, Nielsen T, Rimm DL, Allison KH, Reis-Filho JS, Loibl S, Sotiriou C, Viale G, Badve S, Adams S, Willard-Gallo K and Loi S: The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014. Ann Oncol. 2015 Feb;26 (2) :259-71. Epub 2014 Sep 11. PMID: 25214542

Agarwal S, Hanna J, Sherman ME, Figueroa J and Rimm DL: Quantitative assessment of miR34a as an independent prognostic marker in breast cancer. Br J Cancer. 2015 Jan 6;112 (1) :61-8. Epub 2014 Dec 4. PMID: 25474246

Brown JR, Wimberly H, Lannin DR, Nixon C, Rimm DL and Bossuyt V: Multiplexed quantitative analysis of CD3, CD8, and CD20 predicts response to neoadjuvant chemotherapy in breast cancer. Clin Cancer Res. 2014 Dec 1;20 (23) :5995-6005. Epub 2014 Sep 25. PMID: 25255793

Cheng H, Ballman K, Vassilakopoulou M, Dueck AC, Reinholz MM, Tenner K, Gralow J, Hudis C, Davidson NE, Fountzilas G, McCullough AE, Chen B, Psyrri A, Rimm DL and Perez EA: EGFR expression is associated with decreased benefit from trastuzumab in the NCCTG N9831 (Alliance) trial. Br J Cancer. 2014 Sep 9;111 (6) :1065-71. Epub 2014 Aug 12. PMID: 25117817

Shipitsin M, Small C, Choudhury S, Giladi E, Friedlander S, Nardone J, Hussain S, Hurley AD, Ernst C, Huang YE, Chang H, Nifong TP, Rimm DL, Dunyak J, Loda M, Berman DM and Blume-Jensen P: Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error. Br J Cancer. 2014 Sep 9;111 (6) :1201-12. Epub 2014 Jul 17. PMID: 25032733

Wimberly H, Han G, Pinnaduwage D, Murphy LC, Yang XR, Andrulis IL, Sherman M, Figueroa J and Rimm DL: ERβ splice variant expression in four large cohorts of human breast cancer patient tumors. Breast Cancer Res Treat. 2014 Aug;146 (3) :657-67. Epub 2014 Jul 10. PMID: 25007965

How J, Brown JR, Saylor S and Rimm DL: Macrophage expression of tartrate-resistant acid phosphatase as a prognostic indicator in colon cancer. Histochem Cell Biol. 2014 Aug;142 (2) :195-204. Epub 2014 Jan 16. PMID: 24429833

Wilson MA, Zhao F, Letrero R, D'Andrea K, Rimm DL, Kirkwood JM, Kluger HM, Lee SJ, Schuchter LM, Flaherty KT and Nathanson KL: Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib. Clin Cancer Res. 2014 Jun 15;20 (12) :3328-37. Epub 2014 Apr 8. PMID: 24714776

Psyrri A, Lee JW, Pectasides E, Vassilakopoulou M, Kosmidis EK, Burtness BA, Rimm DL, Wanebo HJ and Forastiere AA: Prognostic biomarkers in phase II trial of cetuximab-containing induction and chemoradiation in resectable HNSCC: Eastern cooperative oncology group E2303. Clin Cancer Res. 2014 Jun 1;20 (11) :3023-32. Epub 2014 Apr 3. PMID: 24700741

Schalper KA, Velcheti V, Carvajal D, Wimberly H, Brown J, Pusztai L and Rimm DL: In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinomas. Clin Cancer Res. 2014 May 15;20 (10) :2773-82. Epub 2014 Mar 19. PMID: 24647569

Cheng H, Bai Y, Sikov W, Sinclair N, Bossuyt V, Abu-Khalaf MM, Harris LN and Rimm DL: Quantitative measurements of HER2 and phospho-HER2 expression: correlation with pathologic response to neoadjuvant chemotherapy and trastuzumab. BMC Cancer. 2014 May 8;14 :326. Epub 2014 May 8. PMID: 24885187

Viray H, Coulter M, Li K, Lane K, Madan A, Mitchell K, Schalper K, Hoyt C and Rimm DL: Automated objective determination of percentage of malignant nuclei for mutation testing. Appl Immunohistochem Mol Morphol. 2014 May-Jun;22 (5) :363-71. PMID: 24162261

Neumeister VM, Parisi F, England AM, Siddiqui S, Anagnostou V, Zarrella E, Vassilakopolou M, Bai Y, Saylor S, Sapino A, Kluger Y, Hicks DG, Bussolati G, Kwei S and Rimm DL: A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue. Lab Invest. 2014 Apr;94 (4) :467-74. Epub 2014 Feb 17. PMID: 24535259

Rimm DL: Next-gen immunohistochemistry. Nat Methods. 2014 Apr;11 (4) :381-3. PMID: 24681723

Rajbhandari P, Schalper KA, Solodin NM, Ellison-Zelski SJ, Ping Lu K, Rimm DL and Alarid ET: Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation. Oncogene. 2014 Mar 13;33 (11) :1438-47. Epub 2013 Apr 1. PMID: 23542176

Schalper KA, Kumar S, Hui P, Rimm DL and Gershkovich P: A retrospective population-based comparison of HER2 immunohistochemistry and fluorescence in situ hybridization in breast carcinomas: impact of 2007 American Society of Clinical Oncology/College of American Pathologists criteria. Arch Pathol Lab Med. 2014 Feb;138 (2) :213-9. Epub 2013 Oct 28. PMID: 24164555

Velcheti V, Schalper KA, Carvajal DE, Anagnostou VK, Syrigos KN, Sznol M, Herbst RS, Gettinger SN, Chen L and Rimm DL: Programmed death ligand-1 expression in non-small cell lung cancer. Lab Invest. 2014 Jan;94 (1) :107-16. Epub 2013 Nov 11. PMID: 24217091

Brown JR, DiGiovanna MP, Killelea B, Lannin DR and Rimm DL: Quantitative assessment Ki-67 score for prediction of response to neoadjuvant chemotherapy in breast cancer. Lab Invest. 2014 Jan;94 (1) :98-106. Epub 2013 Nov 4. PMID: 24189270

Rothberg BE and Rimm DL: Construction and analysis of multiparameter prognostic models for melanoma outcome. Methods Mol Biol. 2014;1102 :227-58. PMID: 24258982

Vassilakopoulou M, Togun T, Dafni U, Cheng H, Bordeaux J, Neumeister VM, Bobos M, Pentheroudakis G, Skarlos DV, Pectasides D, Kotoula V, Fountzilas G, Rimm DL and Psyrri A: In situ quantitative measurement of HER2mRNA predicts benefit from trastuzumab-containing chemotherapy in a cohort of metastatic breast cancer patients. PLoS One. 2014;9 (6) :e99131. Epub 2014 Jun 26. PMID: 24968015

Shipitsin M, Small C, Giladi E, Siddiqui S, Choudhury S, Hussain S, Huang YE, Chang H, Rimm DL, Berman DM, Nifong TP and Blume-Jensen P: Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality. Proteome Sci. 2014;12 :40. Epub 2014 Jul 12. PMID: 25075204

Viray H, Li K, Long TA, Vasalos P, Bridge JA, Jennings LJ, Halling KC, Hameed M and Rimm DL: A prospective, multi-institutional diagnostic trial to determine pathologist accuracy in estimation of percentage of malignant cells. Arch Pathol Lab Med. 2013 Nov;137 (11) :1545-9. PMID: 24168492

Hickerson RP, Wey WC, Rimm DL, Speaker T, Suh S, Flores MA, Gonzalez-Gonzalez E, Leake D, Contag CH and Kaspar RL: Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device. Mol Ther Nucleic Acids. 2013 Oct 22;2 :e129. Epub 2013 Oct 22. PMID: 24150576

Moretti E, Desmedt C, Biagioni C, Regan MM, Oakman C, Larsimont D, Galardi F, Piccart-Gebhart M, Sotiriou C, Rimm DL and Di Leo A: TOP2A protein by quantitative immunofluorescence as a predictor of response to epirubicin in the neoadjuvant treatment of breast cancer. Future Oncol. 2013 Oct;9 (10) :1477-87. PMID: 24106899

Jilaveanu LB, Zhao F, Zito CR, Kirkwood JM, Nathanson KL, D'Andrea K, Wilson M, Rimm DL, Flaherty KT, Lee SJ and Kluger HM: Expression of drug targets in patients treated with sorafenib, carboplatin and paclitaxel. PLoS One. 2013;8 (8) :e69748. Epub 2013 Aug 6. PMID: 23936348

Viray H, Bradley WR, Schalper KA, Rimm DL and Gould Rothberg BE: Marginal and joint distributions of S100, HMB-45, and Melan-A across a large series of cutaneous melanomas. Arch Pathol Lab Med. 2013 Aug;137 (8) :1063-73. PMID: 23899062

Sgroi DC, Carney E, Zarrella E, Steffel L, Binns SN, Finkelstein DM, Szymonifka J, Bhan AK, Shepherd LE, Zhang Y, Schnabel CA, Erlander MG, Ingle JN, Porter P, Muss HB, Pritchard KI, Tu D, Rimm DL and Goss PE: Prediction of late disease recurrence and extended adjuvant letrozole benefit by the HOXB13/IL17BR biomarker. J Natl Cancer Inst. 2013 Jul 17;105 (14) :1036-42. Epub 2013 Jun 28. PMID: 23812955

Velcheti V, Rimm DL and Schalper KA: Sarcomatoid lung carcinomas show high levels of programmed death ligand-1 (PD-L1). J Thorac Oncol. 2013 Jun;8 (6) :803-5. PMID: 23676558

Liu M, Mor G, Cheng H, Xiang X, Hui P, Rutherford T, Yin G, Rimm DL, Holmberg J, Alvero A and Silasi DA: High frequency of putative ovarian cancer stem cells with CD44/CK19 coexpression is associated with decreased progression-free intervals in patients with recurrent epithelial ovarian cancer. Reprod Sci. 2013 May;20 (5) :605-15. Epub 2012 Nov 20. PMID: 23171677

Velcheti V, Schalper K, Yao X, Cheng H, Kocoglu M, Dhodapkar K, Deng Y, Gettinger S and Rimm DL: High SOX2 levels predict better outcome in non-small cell lung carcinomas. PLoS One. 2013;8 (4) :e61427. Epub 2013 Apr 19. PMID: 23620753

Welsh AW, Harigopal M, Wimberly H, Prasad M and Rimm DL: Quantitative analysis of estrogen receptor expression shows SP1 antibody is more sensitive than 1D5. Appl Immunohistochem Mol Morphol. 2013 Mar;21 (2) :139-47. PMID: 22820659

Dolled-Filhart MP and Rimm DL: Gene expression array analysis to determine tissue of origin of carcinoma of unknown primary: cutting edge or already obsolete? Cancer Cytopathol. 2013 Mar;121 (3) :129-35. Epub 2012 Aug 23. PMID: 22927160

Hahn LD, Hoyt C, Rimm DL and Theoharis C: Spatial spectral imaging as an adjunct to the Bethesda classification of thyroid fine-needle aspiration specimens. Cancer Cytopathol. 2013 Mar;121 (3) :162-7. Epub 2012 Jul 25. PMID: 22833451

Portier BP, Wang Z, Downs-Kelly E, Rowe JJ, Patil D, Lanigan C, Budd GT, Hicks DG, Rimm DL and Tubbs RR: Delay to formalin fixation 'cold ischemia time': effect on ERBB2 detection by in-situ hybridization and immunohistochemistry. Mod Pathol. 2013 Jan;26 (1) :1-9. Epub 2012 Aug 17. PMID: 22899285

Bai Y, Cheng H, Bordeaux J, Neumeister V, Kumar S, Rimm DL and Stern DF: Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method. PLoS One. 2013;8 (11) :e79901. Epub 2013 Nov 21. PMID: 24278211

Neumeister VM, Anagnostou V, Siddiqui S, England AM, Zarrella ER, Vassilakopoulou M, Parisi F, Kluger Y, Hicks DG and Rimm DL: Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues. J Natl Cancer Inst. 2012 Dec 5;104 (23) :1815-24. Epub 2012 Oct 22. PMID: 23090068

Neumeister VM, Sullivan CA, Lindner R, Lezon-Geyda K, Li J, Zavada J, Martel M, Glazer PM, Tuck DP, Rimm DL and Harris L: Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer. Breast Cancer Res Treat. 2012 Nov;136 (1) :67-75. Epub 2012 Sep 14. PMID: 22976806

Peck AR, Witkiewicz AK, Liu C, Klimowicz AC, Stringer GA, Pequignot E, Freydin B, Yang N, Ertel A, Tran TH, Girondo MA, Rosenberg AL, Hooke JA, Kovatich AJ, Shriver CD, Rimm DL, Magliocco AM, Hyslop T and Rui H: Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes. Breast Cancer Res. 2012 Oct 4;14 (5) :R130. Epub 2012 Oct 4. PMID: 23036105

Dimou A, Neumeister V, Agarwal S, Anagnostou V, Syrigos K and Rimm DL: Measurement of aldehyde dehydrogenase 1 expression defines a group with better prognosis in patients with non-small cell lung cancer. Am J Pathol. 2012 Oct;181 (4) :1436-42. Epub 2012 Aug 8. PMID: 22877687

Baquero MT, Hanna JA, Neumeister V, Cheng H, Molinaro AM, Harris LN and Rimm DL: Stathmin expression and its relationship to microtubule-associated protein tau and outcome in breast cancer. Cancer. 2012 Oct 1;118 (19) :4660-9. Epub 2012 Feb 22. PMID: 22359235

Hanna JA, Hahn L, Agarwal S and Rimm DL: In situ measurement of miR-205 in malignant melanoma tissue supports its role as a tumor suppressor microRNA. Lab Invest. 2012 Oct;92 (10) :1390-7. Epub 2012 Aug 13. PMID: 22890556

Agarwal S, Gertler FB, Balsamo M, Condeelis JS, Camp RL, Xue X, Lin J, Rohan TE and Rimm DL: Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer. Breast Cancer Res. 2012 Sep 12;14 (5) :R124. Epub 2012 Sep 12. PMID: 22971274

Andre F, Conforti R, Moeder CB, Mauguen A, Arnedos M, Berrada N, Delaloge S, Tomasic G, Spielmann M, Esteva FJ, Rimm DL and Michiels S: Association between the nuclear to cytoplasmic ratio of p27 and the efficacy of adjuvant polychemotherapy in early breast cancer. Ann Oncol. 2012 Aug;23 (8) :2059-64. Epub 2012 Jan 11. PMID: 22241898

Genovese G, Ergun A, Shukla SA, Campos B, Hanna J, Ghosh P, Quayle SN, Rai K, Colla S, Ying H, Wu CJ, Sarkar S, Xiao Y, Zhang J, Zhang H, Kwong L, Dunn K, Wiedemeyer WR, Brennan C, Zheng H, Rimm DL, Collins JJ and Chin L: microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. Cancer Discov. 2012 Aug;2 (8) :736-49. Epub 2012 Jun 29. PMID: 22750848

Feng C, Neumeister V, Ma W, Xu J, Lu L, Bordeaux J, Maihle NJ, Rimm DL and Huang Y: Lin28 regulates HER2 and promotes malignancy through multiple mechanisms. Cell Cycle. 2012 Jul 1;11 (13) :2486-94. Epub 2012 Jul 1. PMID: 22713243

Hanna JA, Wimberly H, Kumar S, Slack F, Agarwal S and Rimm DL: Quantitative analysis of microRNAs in tissue microarrays by in situ hybridization. Biotechniques. 2012 Apr;52 (4) :235-45. PMID: 22482439

Anagnostou VK, Dimou AT, Botsis T, Killiam EJ, Gustavson MD, Homer RJ, Boffa D, Zolota V, Dougenis D, Tanoue L, Gettinger SN, Detterbeck FC, Syrigos KN, Bepler G and Rimm DL: Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay. Cancer. 2012 Mar 15;118 (6) :1607-18. Epub 2011 Aug 25. PMID: 22009766

Lau E, Kluger H, Varsano T, Lee K, Scheffler I, Rimm DL, Ideker T and Ronai ZA: PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. Cell. 2012 Feb 3;148 (3) :543-55. PMID: 22304920

Agarwal S and Rimm DL: Making every cell like HeLa a giant step for cell culture. Am J Pathol. 2012 Feb;180 (2) :443-5. Epub 2011 Dec 20. PMID: 22192626

Welsh AW, Lannin DR, Young GS, Sherman ME, Figueroa JD, Henry NL, Ryden L, Kim C, Love RR, Schiff R and Rimm DL: Cytoplasmic estrogen receptor in breast cancer. Clin Cancer Res. 2012 Jan 1;18 (1) :118-26. Epub 2011 Oct 6. PMID: 21980134

Bordeaux JM, Cheng H, Welsh AW, Haffty BG, Lannin DR, Wu X, Su N, Ma XJ, Luo Y and Rimm DL: Quantitative in situ measurement of estrogen receptor mRNA predicts response to tamoxifen. PLoS One. 2012;7 (5) :e36559. Epub 2012 May 11. PMID: 22606272

Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Gould Rothberg BE, Taketo MM, Dankort D, Rimm DL, McMahon M and Bosenberg M: β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell. 2011 Dec 13;20 (6) :741-54. PMID: 22172720

Michal AM, Peck AR, Tran TH, Liu C, Rimm DL, Rui H and Benovic JL: Differential expression of arrestins is a predictor of breast cancer progression and survival. Breast Cancer Res Treat. 2011 Dec;130 (3) :791-807. Epub 2011 Feb 12. PMID: 21318602

Rimm DL: C-path: a Watson-like visit to the pathology lab. Sci Transl Med. 2011 Nov 9;3 (108) :108fs8. PMID: 22072635

Baquero MT, Lostritto K, Gustavson MD, Bassi KA, Appia F, Camp RL, Molinaro AM, Harris LN and Rimm DL: Evaluation of prognostic and predictive value of microtubule associated protein tau in two independent cohorts. Breast Cancer Res. 2011 Nov 2;13 (5) :R85. Epub 2011 Nov 2. PMID: 21888627

Romeo E, Gustavson MD and Rimm DL: Breast cancer misclassification: a major obstacle to treatment? Womens Health (Lond Engl). 2011 Nov;7 (6) :615-8. PMID: 22040201

Chagpar AB, Camp RL and Rimm DL: Lymph node ratio should be considered for incorporation into staging for breast cancer. Ann Surg Oncol. 2011 Oct;18 (11) :3143-8. Epub 2011 Aug 17. PMID: 21847696

Kumar S, Park SH, Cieply B, Schupp J, Killiam E, Zhang F, Rimm DL and Frisch SM: A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition. Mol Cell Biol. 2011 Oct;31 (19) :4036-51. Epub 2011 Jul 11. PMID: 21746881

Bartlett JM, Rea D and Rimm DL: Quantification of hormone receptors to guide adjuvant therapy choice in early breast cancer: better methods required for improved utility. J Clin Oncol. 2011 Sep 20;29 (27) :3715-6. Epub 2011 Aug 1. PMID: 21810678

Dimou A, Agarwal S, Anagnostou V, Viray H, Christensen S, Gould Rothberg B, Zolota V, Syrigos K and Rimm DL: Standardization of epidermal growth factor receptor (EGFR) measurement by quantitative immunofluorescence and impact on antibody-based mutation detection in non-small cell lung cancer. Am J Pathol. 2011 Aug;179 (2) :580-9. Epub 2011 Jun 12. PMID: 21722621

Welsh AW, Moeder CB, Kumar S, Gershkovich P, Alarid ET, Harigopal M, Haffty BG and Rimm DL: Standardization of estrogen receptor measurement in breast cancer suggests false-negative results are a function of threshold intensity rather than percentage of positive cells. J Clin Oncol. 2011 Aug 1;29 (22) :2978-84. Epub 2011 Jun 27. PMID: 21709197

Bai Y, Tolles J, Cheng H, Siddiqui S, Gopinath A, Pectasides E, Camp RL, Rimm DL and Molinaro AM: Quantitative assessment shows loss of antigenic epitopes as a function of pre-analytic variables. Lab Invest. 2011 Aug;91 (8) :1253-61. Epub 2011 Apr 25. PMID: 21519325

Ni M, Chen Y, Lim E, Wimberly H, Bailey ST, Imai Y, Rimm DL, Liu XS and Brown M: Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell. 2011 Jul 12;20 (1) :119-31. PMID: 21741601

Scott KL, Nogueira C, Heffernan TP, van Doorn R, Dhakal S, Hanna JA, Min C, Jaskelioff M, Xiao Y, Wu CJ, Cameron LA, Perry SR, Zeid R, Feinberg T, Kim M, Vande Woude G, Granter SR, Bosenberg M, Chu GC, DePinho RA, Rimm DL and Chin L: Proinvasion metastasis drivers in early-stage melanoma are oncogenes. Cancer Cell. 2011 Jul 12;20 (1) :92-103. PMID: 21741599

Peck AR, Witkiewicz AK, Liu C, Stringer GA, Klimowicz AC, Pequignot E, Freydin B, Tran TH, Yang N, Rosenberg AL, Hooke JA, Kovatich AJ, Nevalainen MT, Shriver CD, Hyslop T, Sauter G, Rimm DL, Magliocco AM and Rui H: Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure. J Clin Oncol. 2011 Jun 20;29 (18) :2448-58. Epub 2011 May 16. PMID: 21576635

Rimm DL, Nielsen TO, Jewell SD, Rohrer DC, Broadwater G, Waldman F, Mitchell KA, Singh B, Tsongalis GJ, Frankel WL, Magliocco AM, Lara JF, Hsi ED, Bleiweiss IJ, Badve SS, Chen B, Ravdin PM, Schilsky RL, Thor A and Berry DA: Cancer and Leukemia Group B Pathology Committee guidelines for tissue microarray construction representing multicenter prospective clinical trial tissues. J Clin Oncol. 2011 Jun 1;29 (16) :2282-90. Epub 2011 Apr 25. PMID: 21519016

Tolles J, Bai Y, Baquero M, Harris LN, Rimm DL and Molinaro AM: Optimal tumor sampling for immunostaining of biomarkers in breast carcinoma. Breast Cancer Res. 2011 May 18;13 (3) :R51. Epub 2011 May 18. PMID: 21592345

Jilaveanu LB, Zito CR, Aziz SA, Chakraborty A, Davies MA, Camp RL, Rimm DL, Dudek A, Sznol M and Kluger HM: In vitro studies of dasatinib, its targets and predictors of sensitivity. Pigment Cell Melanoma Res. 2011 Apr;24 (2) :386-9. PMID: 21320292

Osborne CK, Neven P, Dirix LY, Mackey JR, Robert J, Underhill C, Schiff R, Gutierrez C, Migliaccio I, Anagnostou VK, Rimm DL, Magill P and Sellers M: Gefitinib or placebo in combination with tamoxifen in patients with hormone receptor-positive metastatic breast cancer: a randomized phase II study. Clin Cancer Res. 2011 Mar 1;17 (5) :1147-59. Epub 2011 Jan 10. PMID: 21220480

Akirav EM, Baquero MT, Opare-Addo LW, Akirav M, Galvan E, Kushner JA, Rimm DL and Herold KC: Glucose and inflammation control islet vascular density and beta-cell function in NOD mice: control of islet vasculature and vascular endothelial growth factor by glucose. Diabetes. 2011 Mar;60 (3) :876-83. Epub 2011 Feb 9. PMID: 21307078

Aziz SA, Jilaveanu LB, Zito C, Camp RL, Rimm DL, Conrad P and Kluger HM: Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma. Clin Cancer Res. 2010 Dec 15;16 (24) :6029-39. PMID: 21169255

Gualberto A, Dolled-Filhart M, Gustavson M, Christiansen J, Wang YF, Hixon ML, Reynolds J, McDonald S, Ang A, Rimm DL, Langer CJ, Blakely J, Garland L, Paz-Ares LG, Karp DD and Lee AV: Molecular analysis of non-small cell lung cancer identifies subsets with different sensitivity to insulin-like growth factor I receptor inhibition. Clin Cancer Res. 2010 Sep 15;16 (18) :4654-65. Epub 2010 Jul 29. PMID: 20670944

Gould Rothberg BE and Rimm DL: Biomarkers: the useful and the not so useful--an assessment of molecular prognostic markers for cutaneous melanoma. J Invest Dermatol. 2010 Aug;130 (8) :1971-87. Epub 2010 Jun 17. PMID: 20555347

VanHouten J, Sullivan C, Bazinet C, Ryoo T, Camp R, Rimm DL, Chung G and Wysolmerski J: PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer. Proc Natl Acad Sci U S A. 2010 Jun 22;107 (25) :11405-10. Epub 2010 Jun 4. PMID: 20534448

Rokicki J, Das PM, Giltnane JM, Wansbury O, Rimm DL, Howard BA and Jones FE: The ERalpha coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium. Mol Cancer. 2010 Jun 15;9 :150. Epub 2010 Jun 15. PMID: 20550710

Betsou F, Rimm DL, Watson PH, Womack C, Hubel A, Coleman RA, Horn L, Terry SF, Zeps N, Clark BJ, Miranda LB, Hewitt RE and Elliott GD: What are the biggest challenges and opportunities for biorepositories in the next three to five years? Biopreserv Biobank. 2010 Jun;8 (2) :81-8. PMID: 24845936

Anagnostou VK, Lowery FJ, Zolota V, Tzelepi V, Gopinath A, Liceaga C, Panagopoulos N, Frangia K, Tanoue L, Boffa D, Gettinger S, Detterbeck F, Homer RJ, Dougenis D, Rimm DL and Syrigos KN: High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology. BMC Cancer. 2010 May 9;10 :186. Epub 2010 May 9. PMID: 20459695

Neumeister V, Agarwal S, Bordeaux J, Camp RL and Rimm DL: In situ identification of putative cancer stem cells by multiplexing ALDH1, CD44, and cytokeratin identifies breast cancer patients with poor prognosis. Am J Pathol. 2010 May;176 (5) :2131-8. Epub 2010 Mar 12. PMID: 20228222

Harigopal M, Barlow WE, Tedeschi G, Porter PL, Yeh IT, Haskell C, Livingston R, Hortobagyi GN, Sledge G, Shapiro C, Ingle JN, Rimm DL and Hayes DF: Multiplexed assessment of the Southwest Oncology Group-directed Intergroup Breast Cancer Trial S9313 by AQUA shows that both high and low levels of HER2 are associated with poor outcome. Am J Pathol. 2010 Apr;176 (4) :1639-47. Epub 2010 Feb 11. PMID: 20150438

Anagnostou VK, Lowery FJ, Syrigos KN, Cagle PT and Rimm DL: Quantitative evaluation of protein expression as a function of tissue microarray core diameter: is a large (1.5 mm) core better than a small (0.6 mm) core? Arch Pathol Lab Med. 2010 Apr;134 (4) :613-9. PMID: 20367312

Anagnostou VK, Welsh AW, Giltnane JM, Siddiqui S, Liceaga C, Gustavson M, Syrigos KN, Reiter JL and Rimm DL: Analytic variability in immunohistochemistry biomarker studies. Cancer Epidemiol Biomarkers Prev. 2010 Apr;19 (4) :982-91. Epub 2010 Mar 23. PMID: 20332259

Nadler Y, González AM, Camp RL, Rimm DL, Kluger HM and Kluger Y: Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer. Ann Oncol. 2010 Mar;21 (3) :466-73. Epub 2009 Aug 28. PMID: 19717535

Mehnert JM, McCarthy MM, Jilaveanu L, Flaherty KT, Aziz S, Camp RL, Rimm DL and Kluger HM: Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays. Hum Pathol. 2010 Mar;41 (3) :375-84. Epub 2009 Dec 11. PMID: 20004943

Siddiqui S and Rimm DL: Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry. Breast Cancer Res. 2010;12 (6) :113. Epub 2010 Dec 20. PMID: 21176180

Parisi F, Gonzalez AM, Nadler Y, Camp RL, Rimm DL, Kluger HM and Kluger Y: Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models. Breast Cancer Res. 2010;12 (5) :R66. Epub 2010 Sep 1. PMID: 20809974

Dolled-Filhart M, Gustavson M, Camp RL, Rimm DL, Tonkinson JL and Christiansen J: Automated analysis of tissue microarrays. Methods Mol Biol. 2010;664 :151-62. PMID: 20690061

Gould Rothberg BE, Berger AJ, Molinaro AM, Subtil A, Krauthammer MO, Camp RL, Bradley WR, Ariyan S, Kluger HM and Rimm DL: Melanoma prognostic model using tissue microarrays and genetic algorithms. J Clin Oncol. 2009 Dec 1;27 (34) :5772-80. Epub 2009 Nov 2. PMID: 19884546

Gaudet MM, Campan M, Figueroa JD, Yang XR, Lissowska J, Peplonska B, Brinton LA, Rimm DL, Laird PW, Garcia-Closas M and Sherman ME: DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18 (11) :3036-43. Epub 2009 Oct 27. PMID: 19861523

Jilaveanu LB, Zito CR, Aziz SA, Conrad PJ, Schmitz JC, Sznol M, Camp RL, Rimm DL and Kluger HM: C-Raf is associated with disease progression and cell proliferation in a subset of melanomas. Clin Cancer Res. 2009 Sep 15;15 (18) :5704-13. Epub 2009 Sep 8. PMID: 19737955

Weinberger PM, Yu Z, Kountourakis P, Sasaki C, Haffty BG, Kowalski D, Merkley MA, Rimm DL, Camp RL and Psyrri A: Defining molecular phenotypes of human papillomavirus-associated oropharyngeal squamous cell carcinoma: validation of three-class hypothesis. Otolaryngol Head Neck Surg. 2009 Sep;141 (3) :382-9. PMID: 19716018

Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, Rimm DL, Wong H, Rodriguez A, Herschkowitz JI, Fan C, Zhang X, He X, Pavlick A, Gutierrez MC, Renshaw L, Larionov AA, Faratian D, Hilsenbeck SG, Perou CM, Lewis MT, Rosen JM and Chang JC: Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009 Aug 18;106 (33) :13820-5. Epub 2009 Aug 3. PMID: 19666588

Scott KL, Kabbarah O, Liang MC, Ivanova E, Anagnostou V, Wu J, Dhakal S, Wu M, Chen S, Feinberg T, Huang J, Saci A, Widlund HR, Fisher DE, Xiao Y, Rimm DL, Protopopov A, Wong KK and Chin L: GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer. Nature. 2009 Jun 25;459 (7250) :1085-90. PMID: 19553991

Anagnostou VK, Bepler G, Syrigos KN, Tanoue L, Gettinger S, Homer RJ, Boffa D, Detterbeck F and Rimm DL: High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma. Clin Cancer Res. 2009 Jun 15;15 (12) :4157-64. Epub 2009 Jun 9. PMID: 19509151

Giltnane JM, Moeder CB, Camp RL and Rimm DL: Quantitative multiplexed analysis of ErbB family coexpression for primary breast cancer prognosis in a large retrospective cohort. Cancer. 2009 Jun 1;115 (11) :2400-9. PMID: 19330842

Harigopal M, Heymann J, Ghosh S, Anagnostou V, Camp RL and Rimm DL: Estrogen receptor co-activator (AIB1) protein expression by automated quantitative analysis (AQUA) in a breast cancer tissue microarray and association with patient outcome. Breast Cancer Res Treat. 2009 May;115 (1) :77-85. Epub 2008 Jun 3. PMID: 18521745

Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y and Kluger HM: Phosphatidylinositol-3-kinase as a therapeutic target in melanoma. Clin Cancer Res. 2009 May 1;15 (9) :3029-36. Epub 2009 Apr 21. PMID: 19383818

Horst B, Gruvberger-Saal SK, Hopkins BD, Bordone L, Yang Y, Chernoff KA, Uzoma I, Schwipper V, Liebau J, Nowak NJ, Brunner G, Owens D, Rimm DL, Parsons R and Celebi JT: Gab2-mediated signaling promotes melanoma metastasis. Am J Pathol. 2009 Apr;174 (4) :1524-33. PMID: 19342374

Gould Rothberg BE, Bracken MB and Rimm DL: Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2009 Apr 1;101 (7) :452-74. Epub 2009 Mar 24. PMID: 19318635

Agarwal S, Zerillo C, Kolmakova J, Christensen JG, Harris LN, Rimm DL, Digiovanna MP and Stern DF: Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells. Br J Cancer. 2009 Mar 24;100 (6) :941-9. Epub 2009 Feb 24. PMID: 19240716

Liu J, Ghanim M, Xue L, Brown CD, Iossifov I, Angeletti C, Hua S, Nègre N, Ludwig M, Stricker T, Al-Ahmadie HA, Tretiakova M, Camp RL, Perera-Alberto M, Rimm DL, Xu T, Rzhetsky A and White KP: Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. Science. 2009 Feb 27;323 (5918) :1218-22. Epub 2009 Jan 22. PMID: 19164706

Jilaveanu L, Zito C, Lee SJ, Nathanson KL, Camp RL, Rimm DL, Flaherty KT and Kluger HM: Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib. Clin Cancer Res. 2009 Feb 1;15 (3) :1076-85. PMID: 19188183

Sullivan CA, Ghosh S, Ocal IT, Camp RL, Rimm DL and Chung GG: Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer. Hum Pathol. 2009 Feb;40 (2) :156-65. Epub 2008 Sep 16. PMID: 18799189

Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL and Moon RT: Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci U S A. 2009 Jan 27;106 (4) :1193-8. Epub 2009 Jan 14. PMID: 19144919

Anagnostou VK, Syrigos KN, Bepler G, Homer RJ and Rimm DL: Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma. J Clin Oncol. 2009 Jan 10;27 (2) :271-8. Epub 2008 Dec 8. PMID: 19064983

Hanna JA, Bordeaux J, Rimm DL and Agarwal S: The function, proteolytic processing, and histopathology of Met in cancer. Adv Cancer Res. 2009;103 :1-23. PMID: 19854350

Emerson JW, Dolled-Filhart M, Harris L, Rimm DL and Tuck DP: Quantitative assessment of tissue biomarkers and construction of a model to predict outcome in breast cancer using multiple imputation. Cancer Inform. 2009;7 :29-40. Epub 2008 Dec 23. PMID: 19352457

Moeder CB, Giltnane JM, Moulis SP and Rimm DL: Quantitative, fluorescence-based in-situ assessment of protein expression. Methods Mol Biol. 2009;520 :163-75. PMID: 19381954

Ghosh S, Sullivan CA, Zerkowski MP, Molinaro AM, Rimm DL, Camp RL and Chung GG: High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer. Hum Pathol. 2008 Dec;39 (12) :1835-43. Epub 2008 Aug 20. PMID: 18715621

Camp RL, Neumeister V and Rimm DL: A decade of tissue microarrays: progress in the discovery and validation of cancer biomarkers. J Clin Oncol. 2008 Dec 1;26 (34) :5630-7. Epub 2008 Oct 20. PMID: 18936473

Gustavson MD, Molinaro AM, Tedeschi G, Camp RL and Rimm DL: AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. Arch Pathol Lab Med. 2008 Nov;132 (11) :1746-52. PMID: 18976010

Giltnane JM, Molinaro A, Cheng H, Robinson A, Turbin D, Gelmon K, Huntsman D and Rimm DL: Comparison of quantitative immunofluorescence with conventional methods for HER2/neu testing with respect to response to trastuzumab therapy in metastatic breast cancer. Arch Pathol Lab Med. 2008 Oct;132 (10) :1635-47. PMID: 18834223

Rothberg BE, Moeder CB, Kluger H, Halaban R, Elder DE, Murphy GF, Lazar A, Prieto V, Duncan LM and Rimm DL: Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions. Mod Pathol. 2008 Sep;21 (9) :1121-9. Epub 2008 Jun 13. PMID: 18552823

Nadler Y, Camp RL, Schwartz C, Rimm DL, Kluger HM and Kluger Y: Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer. Clin Cancer Res. 2008 Jul 15;14 (14) :4455-62. PMID: 18628459

Kreizenbeck GM, Berger AJ, Subtil A, Rimm DL and Gould Rothberg BE: Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev. 2008 Apr;17 (4) :949-58. PMID: 18398036

McCarthy MM, Pick E, Kluger Y, Gould-Rothberg B, Lazova R, Camp RL, Rimm DL and Kluger HM: HSP90 as a marker of progression in melanoma. Ann Oncol. 2008 Mar;19 (3) :590-4. Epub 2007 Nov 23. PMID: 18037622

Mansoor I, Zalles C, Zahid F, Gossage K, Levenson RM and Rimm DL: Fine-needle aspiration of follicular adenoma versus parathyroid adenoma: the utility of multispectral imaging in differentiating lesions with subtle cytomorphologic differences. Cancer. 2008 Feb 25;114 (1) :22-6. PMID: 18085636

Nadler Y, Camp RL, Giltnane JM, Moeder C, Rimm DL, Kluger HM and Kluger Y: Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer. Breast Cancer Res. 2008;10 (2) :R35. Epub 2008 Apr 23. PMID: 18430249

Hua S, Kallen CB, Dhar R, Baquero MT, Mason CE, Russell BA, Shah PK, Liu J, Khramtsov A, Tretiakova MS, Krausz TN, Olopade OI, Rimm DL and White KP: Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression. Mol Syst Biol. 2008;4 :188. Epub 2008 Apr 15. PMID: 18414489

Moeder CB, Giltnane JM, Harigopal M, Molinaro A, Robinson A, Gelmon K, Huntsman D, Camp RL and Rimm DL: Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome. J Clin Oncol. 2007 Dec 1;25 (34) :5418-25. PMID: 18048824

Yang XR, Pfeiffer RM, Garcia-Closas M, Rimm DL, Lissowska J, Brinton LA, Peplonska B, Hewitt SM, Cartun RW, Mandich D, Sasano H, Evans DB, Sutter TR and Sherman ME: Hormonal markers in breast cancer: coexpression, relationship with pathologic characteristics, and risk factor associations in a population-based study. Cancer Res. 2007 Nov 1;67 (21) :10608-17. Epub 2007 Oct 29. PMID: 17968031

Sherman ME, Rimm DL, Yang XR, Chatterjee N, Brinton LA, Lissowska J, Peplonska B, Szeszenia-Dabrowska N, Zatonski W, Cartun R, Mandich D, Rymkiewicz G, Ligaj M, Lukaszek S, Kordek R, Kalaylioglu Z, Harigopal M, Charrette L, Falk RT, Richesson D, Anderson WF, Hewitt SM and García-Closas M: Variation in breast cancer hormone receptor and HER2 levels by etiologic factors: a population-based analysis. Int J Cancer. 2007 Sep 1;121 (5) :1079-85. PMID: 17487843

Giltnane JM, Rydén L, Cregger M, Bendahl PO, Jirström K and Rimm DL: Quantitative measurement of epidermal growth factor receptor is a negative predictive factor for tamoxifen response in hormone receptor positive premenopausal breast cancer. J Clin Oncol. 2007 Jul 20;25 (21) :3007-14. PMID: 17634479

Boucheron LE, Bi Z, Harvey NR, Manjunath B and Rimm DL: Utility of multispectral imaging for nuclear classification of routine clinical histopathology imagery. BMC Cell Biol. 2007 Jul 10;8 Suppl 1 :S8. Epub 2007 Jul 10. PMID: 17634098

Chung GG, Zerkowski MP, Ghosh S, Camp RL and Rimm DL: Quantitative analysis of estrogen receptor heterogeneity in breast cancer. Lab Invest. 2007 Jul;87 (7) :662-9. Epub 2007 Mar 5. PMID: 17334408

Rimm DL, Giltnane JM, Moeder C, Harigopal M, Chung GG, Camp RL and Burtness B: Bimodal population or pathologist artifact? J Clin Oncol. 2007 Jun 10;25 (17) :2487-8. PMID: 17557963

Pick E, Kluger Y, Giltnane JM, Moeder C, Camp RL, Rimm DL and Kluger HM: High HSP90 expression is associated with decreased survival in breast cancer. Cancer Res. 2007 Apr 1;67 (7) :2932-7. PMID: 17409397

Reshetnikova G, Troyanovsky S and Rimm DL: Definition of a direct extracellular interaction between Met and E-cadherin. Cell Biol Int. 2007 Apr;31 (4) :366-73. Epub 2007 Jan 21. PMID: 17336101

Yang XR, Sherman ME, Rimm DL, Lissowska J, Brinton LA, Peplonska B, Hewitt SM, Anderson WF, Szeszenia-Dabrowska N, Bardin-Mikolajczak A, Zatonski W, Cartun R, Mandich D, Rymkiewicz G, Ligaj M, Lukaszek S, Kordek R and García-Closas M: Differences in risk factors for breast cancer molecular subtypes in a population-based study. Cancer Epidemiol Biomarkers Prev. 2007 Mar;16 (3) :439-43. PMID: 17372238

Pozner-Moulis S, Cregger M, Camp RL and Rimm DL: Antibody validation by quantitative analysis of protein expression using expression of Met in breast cancer as a model. Lab Invest. 2007 Mar;87 (3) :251-60. Epub 2007 Jan 29. PMID: 17260003

Shields JM, Thomas NE, Cregger M, Berger AJ, Leslie M, Torrice C, Hao H, Penland S, Arbiser J, Scott G, Zhou T, Bar-Eli M, Bear JE, Der CJ, Kaufmann WK, Rimm DL and Sharpless NE: Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma. Cancer Res. 2007 Feb 15;67 (4) :1502-12. PMID: 17308088

Zerkowski MP, Camp RL, Burtness BA, Rimm DL and Chung GG: Quantitative analysis of breast cancer tissue microarrays shows high cox-2 expression is associated with poor outcome. Cancer Invest. 2007 Feb;25 (1) :19-26. PMID: 17364553

Kluger HM, McCarthy MM, Alvero AB, Sznol M, Ariyan S, Camp RL, Rimm DL and Mor G: The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization. J Transl Med. 2007 Jan 26;5 :6. Epub 2007 Jan 26. PMID: 17257402

Bamias A, Yu Z, Weinberger PM, Markakis S, Kowalski D, Camp RL, Rimm DL, Dimopoulos MA and Psyrri A: Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer. Ann Oncol. 2006 Dec;17 (12) :1797-802. Epub 2006 Sep 13. PMID: 16971669

Bellovin DI, Simpson KJ, Danilov T, Maynard E, Rimm DL, Oettgen P and Mercurio AM: Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma. Oncogene. 2006 Nov 2;25 (52) :6959-67. Epub 2006 May 22. PMID: 16715134

Dolled-Filhart M, Rydén L, Cregger M, Jirström K, Harigopal M, Camp RL and Rimm DL: Classification of breast cancer using genetic algorithms and tissue microarrays. Clin Cancer Res. 2006 Nov 1;12 (21) :6459-68. PMID: 17085660

Yang XR, Charette LA, Garcia-Closas M, Lissowska J, Paal E, Sidawy M, Hewitt SM, Rimm DL and Sherman ME: Construction and validation of tissue microarrays of ductal carcinoma in situ and terminal duct lobular units associated with invasive breast carcinoma. Diagn Mol Pathol. 2006 Sep;15 (3) :157-61. PMID: 16932071

Pozner-Moulis S, Pappas DJ and Rimm DL: Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density. Cancer Res. 2006 Aug 15;66 (16) :7976-82. PMID: 16912172

Giltnane JM, Murren JR, Rimm DL and King BL: AQUA and FISH analysis of HER-2/neu expression and amplification in a small cell lung carcinoma tissue microarray. Histopathology. 2006 Aug;49 (2) :161-9. PMID: 16879393

Rimm DL: What brown cannot do for you. Nat Biotechnol. 2006 Aug;24 (8) :914-6. PMID: 16900128

Rimm DL: What's in a name? Arch Pathol Lab Med. 2006 Jul;130 (7) :934-5. PMID: 16831045

Cregger M, Berger AJ and Rimm DL: Immunohistochemistry and quantitative analysis of protein expression. Arch Pathol Lab Med. 2006 Jul;130 (7) :1026-30. PMID: 16831029

McCarthy MM, DiVito KA, Sznol M, Kovacs D, Halaban R, Berger AJ, Flaherty KT, Camp RL, Lazova R, Rimm DL and Kluger HM: Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma. Clin Cancer Res. 2006 Jun 15;12 (12) :3856-63. PMID: 16778114

Cowan JD, Rimm DL and Tuck DP: Cruella: developing a scalable tissue microarray data management system. Arch Pathol Lab Med. 2006 Jun;130 (6) :817-22. PMID: 16740033

Psyrri A, Yu Z, Bamias A, Weinberger PM, Markakis S, Kowalski D, Camp RL, Rimm DL and Dimopoulos MA: Evaluation of the prognostic value of cellular inhibitor of apoptosis protein in epithelial ovarian cancer using automated quantitative protein analysis. Cancer Epidemiol Biomarkers Prev. 2006 Jun;15 (6) :1179-83. PMID: 16775178

Dolled-Filhart M, McCabe A, Giltnane J, Cregger M, Camp RL and Rimm DL: Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome. Cancer Res. 2006 May 15;66 (10) :5487-94. PMID: 16707478

Pappas DJ and Rimm DL: Direct interaction of the C-terminal domain of alpha-catenin and F-actin is necessary for stabilized cell-cell adhesion. Cell Commun Adhes. 2006 May-Jun;13 (3) :151-70. PMID: 16798615

Ghofrani M, Beckman D and Rimm DL: The value of onsite adequacy assessment of thyroid fine-needle aspirations is a function of operator experience. Cancer. 2006 Apr 25;108 (2) :110-3. PMID: 16400635

Chung GG, Yoon HH, Zerkowski MP, Ghosh S, Thomas L, Harigopal M, Charette LA, Salem RR, Camp RL, Rimm DL and Burtness BA: Vascular endothelial growth factor, FLT-1, and FLK-1 analysis in a pancreatic cancer tissue microarray. Cancer. 2006 Apr 15;106 (8) :1677-84. PMID: 16532435

Weinberger PM, Yu Z, Haffty BG, Kowalski D, Harigopal M, Brandsma J, Sasaki C, Joe J, Camp RL, Rimm DL and Psyrri A: Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis. J Clin Oncol. 2006 Feb 10;24 (5) :736-47. Epub 2006 Jan 9. PMID: 16401683

McCabe A, Dolled-Filhart M, Camp RL and Rimm DL: Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis. J Natl Cancer Inst. 2005 Dec 21;97 (24) :1808-15. PMID: 16368942

Psyrri A, Kassar M, Yu Z, Bamias A, Weinberger PM, Markakis S, Kowalski D, Camp RL, Rimm DL and Dimopoulos MA: Effect of epidermal growth factor receptor expression level on survival in patients with epithelial ovarian cancer. Clin Cancer Res. 2005 Dec 15;11 (24 Pt 1) :8637-43. PMID: 16361548

Berger AJ, Davis DW, Tellez C, Prieto VG, Gershenwald JE, Johnson MM, Rimm DL and Bar-Eli M: Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction. Cancer Res. 2005 Dec 1;65 (23) :11185-92. PMID: 16322269

Bellovin DI, Bates RC, Muzikansky A, Rimm DL and Mercurio AM: Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease. Cancer Res. 2005 Dec 1;65 (23) :10938-45. PMID: 16322241

Psyrri A, Bamias A, Yu Z, Weinberger PM, Kassar M, Markakis S, Kowalski D, Efstathiou E, Camp RL, Rimm DL and Dimopoulos MA: Subcellular localization and protein levels of cyclin-dependent kinase inhibitor p27 independently predict for survival in epithelial ovarian cancer. Clin Cancer Res. 2005 Dec 1;11 (23) :8384-90. PMID: 16322299

Angeletti C, Harvey NR, Khomitch V, Fischer AH, Levenson RM and Rimm DL: Detection of malignancy in cytology specimens using spectral-spatial analysis. Lab Invest. 2005 Dec;85 (12) :1555-64. PMID: 16200074

Siddiqui SF, Pawelek J, Handerson T, Lin CY, Dickson RB, Rimm DL and Camp RL: Coexpression of beta1,6-N-acetylglucosaminyltransferase V glycoprotein substrates defines aggressive breast cancers with poor outcome. Cancer Epidemiol Biomarkers Prev. 2005 Nov;14 (11 Pt 1) :2517-23. PMID: 16284372

Choi DH, Kim S, Rimm DL, Carter D and Haffty BG: Immunohistochemical biomarkers in patients with early-onset breast carcinoma by tissue microarray. Cancer J. 2005 Sep-Oct;11 (5) :404-11. PMID: 16259871

Bast RC Jr, Lilja H, Urban N, Rimm DL, Fritsche H, Gray J, Veltri R, Klee G, Allen A, Kim N, Gutman S, Rubin MA and Hruszkewycz A: Translational crossroads for biomarkers. Clin Cancer Res. 2005 Sep 1;11 (17) :6103-8. PMID: 16144908

McCarthy MM, Sznol M, DiVito KA, Camp RL, Rimm DL and Kluger HM: Evaluating the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in breast cancer. Clin Cancer Res. 2005 Jul 15;11 (14) :5188-94. PMID: 16033835

Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE and Sellers WR: Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature. 2005 Jul 7;436 (7047) :117-22. PMID: 16001072

Kluger HM, Chelouche Lev D, Kluger Y, McCarthy MM, Kiriakova G, Camp RL, Rimm DL and Price JE: Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease. Cancer Res. 2005 Jul 1;65 (13) :5578-87. PMID: 15994930

Rimm DL: Tissue microarrays without cores. Nat Methods. 2005 Jul;2 (7) :492-3. PMID: 15973417

Harigopal M, Berger AJ, Camp RL, Rimm DL and Kluger HM: Automated quantitative analysis of E-cadherin expression in lymph node metastases is predictive of survival in invasive ductal breast cancer. Clin Cancer Res. 2005 Jun 1;11 (11) :4083-9. PMID: 15930343

Fadare O, Mariappan MR, Hileeto D, Wang S, McAlpine JN and Rimm DL: Upstaging based solely on positive peritoneal washing does not affect outcome in endometrial cancer. Mod Pathol. 2005 May;18 (5) :673-80. PMID: 15578078

Provost E, McCabe A, Stern J, Lizardi I, D'Aquila TG and Rimm DL: Functional correlates of mutation of the Asp32 and Gly34 residues of beta-catenin. Oncogene. 2005 Apr 14;24 (16) :2667-76. PMID: 15829978

Yu Z, Weinberger PM, Provost E, Haffty BG, Sasaki C, Joe J, Camp RL, Rimm DL and Psyrri A: beta-Catenin functions mainly as an adhesion molecule in patients with squamous cell cancer of the head and neck. Clin Cancer Res. 2005 Apr 1;11 (7) :2471-7. PMID: 15814622

Yu Z, Weinberger PM, Haffty BG, Sasaki C, Zerillo C, Joe J, Kowalski D, Dziura J, Camp RL, Rimm DL and Psyrri A: Cyclin d1 is a valuable prognostic marker in oropharyngeal squamous cell carcinoma. Clin Cancer Res. 2005 Feb 1;11 (3) :1160-6. PMID: 15709184

Higgins SA, Matloff ET, Rimm DL, Dziura J, Haffty BG and King BL: Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer. Breast Cancer Res. 2005;7 (6) :R1017-22. Epub 2005 Oct 24. PMID: 16280052

Koullias GJ, Ravichandran P, Korkolis DP, Rimm DL and Elefteriades JA: Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections. Ann Thorac Surg. 2004 Dec;78 (6) :2106-10; discussion 2110-1. PMID: 15561045

Divito KA, Berger AJ, Camp RL, Dolled-Filhart M, Rimm DL and Kluger HM: Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma. Cancer Res. 2004 Dec 1;64 (23) :8773-7. PMID: 15574790

Berger AJ, Camp RL, Divito KA, Kluger HM, Halaban R and Rimm DL: Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome. Cancer Res. 2004 Dec 1;64 (23) :8767-72. PMID: 15574789

Giltnane JM and Rimm DL: Technology insight: Identification of biomarkers with tissue microarray technology. Nat Clin Pract Oncol. 2004 Dec;1 (2) :104-11. PMID: 16264828

Camp RL, Dolled-Filhart M and Rimm DL: X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization. Clin Cancer Res. 2004 Nov 1;10 (21) :7252-9. PMID: 15534099

Weinberger PM, Yu Z, Haffty BG, Kowalski D, Harigopal M, Sasaki C, Rimm DL and Psyrri A: Prognostic significance of p16 protein levels in oropharyngeal squamous cell cancer. Clin Cancer Res. 2004 Sep 1;10 (17) :5684-91. PMID: 15355894

Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE and Halaban R: Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res. 2004 Aug 1;64 (15) :5270-82. PMID: 15289333

DiVito KA, Charette LA, Rimm DL and Camp RL: Long-term preservation of antigenicity on tissue microarrays. Lab Invest. 2004 Aug;84 (8) :1071-8. PMID: 15195116

Angeletti C, Khomitch V, Halaban R and Rimm DL: Novel tyramide-based tyrosinase assay for the detection of melanoma cells in cytological preparations. Diagn Cytopathol. 2004 Jul;31 (1) :33-7. PMID: 15236262

Jaganath R, Angeletti C, Levenson R and Rimm DL: Diagnostic classification of urothelial cells in urine cytology specimens using exclusively spectral information. Cancer. 2004 Jun 25;102 (3) :186-91. PMID: 15211478

Fadare O, Mariappan MR, Wang S, Hileeto D, McAlpine J and Rimm DL: The histologic subtype of ovarian tumors affects the detection rate by pelvic washings. Cancer. 2004 Jun 25;102 (3) :150-6. PMID: 15211473

Chelouche-Lev D, Kluger HM, Berger AJ, Rimm DL and Price JE: alphaB-crystallin as a marker of lymph node involvement in breast carcinoma. Cancer. 2004 Jun 15;100 (12) :2543-8. PMID: 15197794

Kluger HM, DiVito K, Berger AJ, Halaban R, Ariyan S, Camp RL and Rimm DL: Her2/neu is not a commonly expressed therapeutic target in melanoma -- a large cohort tissue microarray study. Melanoma Res. 2004 Jun;14 (3) :207-10. PMID: 15179190

Chung GG, Zerkowski MP, Ocal IT, Dolled-Filhart M, Kang JY, Psyrri A, Camp RL and Rimm DL: beta-Catenin and p53 analyses of a breast carcinoma tissue microarray. Cancer. 2004 May 15;100 (10) :2084-92. PMID: 15139049

Rubin MA, Zerkowski MP, Camp RL, Kuefer R, Hofer MD, Chinnaiyan AM and Rimm DL: Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements. Am J Pathol. 2004 Mar;164 (3) :831-40. PMID: 14982837

Kluger HM, Dolled-Filhart M, Rodov S, Kacinski BM, Camp RL and Rimm DL: Macrophage colony-stimulating factor-1 receptor expression is associated with poor outcome in breast cancer by large cohort tissue microarray analysis. Clin Cancer Res. 2004 Jan 1;10 (1 Pt 1) :173-7. PMID: 14734466

Berger AJ, Kluger HM, Li N, Kielhorn E, Halaban R, Ronai Z and Rimm DL: Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival. Cancer Res. 2003 Dec 1;63 (23) :8103-7. PMID: 14678960

Provost E, Yamamoto Y, Lizardi I, Stern J, D'Aquila TG, Gaynor RB and Rimm DL: Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites. J Biol Chem. 2003 Aug 22;278 (34) :31781-9. Epub 2003 Jun 10. PMID: 12799363

Xie W, Rimm DL, Lin Y, Shih WJ and Reiss M: Loss of Smad signaling in human colorectal cancer is associated with advanced disease and poor prognosis. Cancer J. 2003 Jul-Aug;9 (4) :302-12. PMID: 12967141

Tolgay Ocal I, Dolled-Filhart M, D'Aquila TG, Camp RL and Rimm DL: Tissue microarray-based studies of patients with lymph node negative breast carcinoma show that met expression is associated with worse outcome but is not correlated with epidermal growth factor family receptors. Cancer. 2003 Apr 15;97 (8) :1841-8. PMID: 12673709

Camp RL, Dolled-Filhart M, King BL and Rimm DL: Quantitative analysis of breast cancer tissue microarrays shows that both high and normal levels of HER2 expression are associated with poor outcome. Cancer Res. 2003 Apr 1;63 (7) :1445-8. PMID: 12670887

King BL, Tsai SC, Gryga ME, D'Aquila TG, Seelig SA, Morrison LE, Jacobson KK, Legator MS, Ward DC, Rimm DL and Phillips RF: Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization. Clin Cancer Res. 2003 Apr;9 (4) :1509-16. PMID: 12684427

Kang JY, Dolled-Filhart M, Ocal IT, Singh B, Lin CY, Dickson RB, Rimm DL and Camp RL: Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer. Cancer Res. 2003 Mar 1;63 (5) :1101-5. PMID: 12615728

Kielhorn E, Provost E, Olsen D, D'Aquila TG, Smith BL, Camp RL and Rimm DL: Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome. Int J Cancer. 2003 Feb 20;103 (5) :652-6. PMID: 12494474

Dolled-Filhart M, Camp RL, Kowalski DP, Smith BL and Rimm DL: Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis. Clin Cancer Res. 2003 Feb;9 (2) :594-600. PMID: 12576423

Xie W, Bharathy S, Kim D, Haffty BG, Rimm DL and Reiss M: Frequent alterations of Smad signaling in human head and neck squamous cell carcinomas: a tissue microarray analysis. Oncol Res. 2003;14 (2) :61-73. PMID: 14649540

Camp RL, Chung GG and Rimm DL: Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med. 2002 Nov;8 (11) :1323-7. Epub 2002 Oct 21. PMID: 12389040

Ernst LM and Rimm DL: Quantitative examination of mechanophysical tumor cell enrichment in fine-needle aspiration specimens. Cancer. 2002 Oct 25;96 (5) :275-9. PMID: 12378594

Dillon DA, Hipolito E, Zheng K, Rimm DL and Costa JC: p53 mutations as tumor markers in fine needle aspirates of palpable breast masses. Acta Cytol. 2002 Sep-Oct;46 (5) :841-7. PMID: 12365217

King BL, Crisi GM, Tsai SC, Haffty BG, Phillips RF and Rimm DL: Immunocytochemical analysis of breast cells obtained by ductal lavage. Cancer. 2002 Aug 25;96 (4) :244-9. PMID: 12209667

Chung GG, Kielhorn EP and Rimm DL: Subjective differences in outcome are seen as a function of the immunohistochemical method used on a colorectal cancer tissue microarray. Clin Colorectal Cancer. 2002 Feb;1 (4) :237-42. PMID: 12450422

Xie W, Mertens JC, Reiss DJ, Rimm DL, Camp RL, Haffty BG and Reiss M: Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. Cancer Res. 2002 Jan 15;62 (2) :497-505. PMID: 11809701

Kielhorn E, Schofield K and Rimm DL: Use of magnetic enrichment for detection of carcinoma cells in fluid specimens. Cancer. 2002 Jan 1;94 (1) :205-11. PMID: 11815978

Chung GG, Provost E, Kielhorn EP, Charette LA, Smith BL and Rimm DL: Tissue microarray analysis of beta-catenin in colorectal cancer shows nuclear phospho-beta-catenin is associated with a better prognosis. Clin Cancer Res. 2001 Dec;7 (12) :4013-20. PMID: 11751495

Chen T, Yan W, Wells RG, Rimm DL, McNiff J, Leffell D and Reiss M: Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases. Int J Cancer. 2001 Sep 1;93 (5) :653-61. PMID: 11477574

Rimm DL, Camp RL, Charette LA, Olsen DA and Provost E: Amplification of tissue by construction of tissue microarrays. Exp Mol Pathol. 2001 Jun;70 (3) :255-64. PMID: 11418004

Rimm DL: Impact of microarray technologies on cytopathology. Overview of technologies and commentary on current and future implications for pathologists and cytopathologists. Acta Cytol. 2001 Mar-Apr;45 (2) :111-4. PMID: 11284295

Garcia-Rostan G, Camp RL, Herrero A, Carcangiu ML, Rimm DL and Tallini G: Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis. Am J Pathol. 2001 Mar;158 (3) :987-96. PMID: 11238046

Pradhan D, Lombardo CR, Roe S, Rimm DL and Morrow JS: alpha -Catenin binds directly to spectrin and facilitates spectrin-membrane assembly in vivo. J Biol Chem. 2001 Feb 9;276 (6) :4175-81. Epub 2000 Nov 7. PMID: 11069925

Flynn K and Rimm DL: Diagnosis of "ASCUS" in women over age 50 is less likely to be associated with dysplasia. Diagn Cytopathol. 2001 Feb;24 (2) :132-6. PMID: 11169895

Reyes-Múgica M, Meyerhardt JA, Rzasa J, Rimm DL, Johnson KR, Wheelock MJ and Reale MA: Truncated DCC reduces N-cadherin/catenin expression and calcium-dependent cell adhesion in neuroblastoma cells. Lab Invest. 2001 Feb;81 (2) :201-10. PMID: 11232642

Rimm DL, Camp RL, Charette LA, Costa J, Olsen DA and Reiss M: Tissue microarray: a new technology for amplification of tissue resources. Cancer J. 2001 Jan-Feb;7 (1) :24-31. PMID: 11269645

Camp RL, Charette LA and Rimm DL: Validation of tissue microarray technology in breast carcinoma. Lab Invest. 2000 Dec;80 (12) :1943-9. PMID: 11140706

Rimm DL and Sherman ME: The new Molecular Biology Section of Acta Cytologica. An introduction. Acta Cytol. 2000 Sep-Oct;44 (5) :701-2. PMID: 11015969

Dillon DA, Johnson CC, Topazian MD, Tallini G, Rimm DL and Costa JC: The utility of Ki-ras mutation analysis in the cytologic diagnosis of pancreatobiliary neoplasma. Cancer J. 2000 Sep-Oct;6 (5) :294-301. PMID: 11079168

Camp RL, Rimm EB and Rimm DL: Author reply Cancer. 2000 Jul 1;89 (1) :218-9. PMID: 10897021

Schofield K, D'Aquila T and Rimm DL: E-cadherin expression is a sensitive and specific method for detection of carcinoma cells in fluid specimens. Diagn Cytopathol. 2000 May;22 (5) :263-7. PMID: 10790230

Rimm DL: Molecular biology in cytopathology: current applications and future directions. Cancer. 2000 Feb 25;90 (1) :1-9. PMID: 10692210

Camp RL, Rimm EB and Rimm DL: A high number of tumor free axillary lymph nodes from patients with lymph node negative breast carcinoma is associated with poor outcome. Cancer. 2000 Jan 1;88 (1) :108-13. PMID: 10618612

Camp RL, Rimm EB and Rimm DL: Met expression is associated with poor outcome in patients with axillary lymph node negative breast carcinoma. Cancer. 1999 Dec 1;86 (11) :2259-65. PMID: 10590366

Provost E and Rimm DL: Controversies at the cytoplasmic face of the cadherin-based adhesion complex. Curr Opin Cell Biol. 1999 Oct;11 (5) :567-72. PMID: 10508647

Ilan N, Mahooti S, Rimm DL and Madri JA: PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated beta-catenin. J Cell Sci. 1999 Sep;112 Pt 18 :3005-14. PMID: 10462517

Caca K, Kolligs FT, Ji X, Hayes M, Qian J, Yahanda A, Rimm DL, Costa J and Fearon ER: Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer. Cell Growth Differ. 1999 Jun;10 (6) :369-76. PMID: 10392898

Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML and Rimm DL: Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res. 1999 Apr 15;59 (8) :1811-5. PMID: 10213482

Rimm DL, Caca K, Hu G, Harrison FB and Fearon ER: Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. Am J Pathol. 1999 Feb;154 (2) :325-9. PMID: 10027390

Gold JS, Reynolds AB and Rimm DL: Loss of p120ctn in human colorectal cancer predicts metastasis and poor survival. Cancer Lett. 1998 Oct 23;132 (1-2) :193-201. PMID: 10397474

Magda JL, Minger BA and Rimm DL: Polymerase chain reaction-based detection of clonality as a non-morphologic diagnostic tool for fine-needle aspiration of the breast. Cancer. 1998 Aug 25;84 (4) :262-7. PMID: 9723602

Roe S, Koslov ER and Rimm DL: A mutation in alpha-catenin disrupts adhesion in clone A cells without perturbing its actin and beta-catenin binding activity. Cell Adhes Commun. 1998 Jun;5 (4) :283-96. PMID: 9762469

Ghoussoub RA, Dillon DA, D'Aquila T, Rimm EB, Fearon ER and Rimm DL: Expression of c-met is a strong independent prognostic factor in breast carcinoma. Cancer. 1998 Apr 15;82 (8) :1513-20. PMID: 9554529

Brady-Kalnay SM, Mourton T, Nixon JP, Pietz GE, Kinch M, Chen H, Brackenbury R, Rimm DL, Del Vecchio RL and Tonks NK: Dynamic interaction of PTPmu with multiple cadherins in vivo. J Cell Biol. 1998 Apr 6;141 (1) :287-96. PMID: 9531566

Dillon DA, D'Aquila T, Reynolds AB, Fearon ER and Rimm DL: The expression of p120ctn protein in breast cancer is independent of alpha- and beta-catenin and E-cadherin. Am J Pathol. 1998 Jan;152 (1) :75-82. PMID: 9422525

Hazan RB, Kang L, Roe S, Borgen PI and Rimm DL: Vinculin is associated with the E-cadherin adhesion complex. J Biol Chem. 1997 Dec 19;272 (51) :32448-53. PMID: 9405455

Gold JS, Bao L, Ghoussoub RA, Zetter BR and Rimm DL: Localization and quantitation of expression of the cell motility-related protein thymosin beta15 in human breast tissue. Mod Pathol. 1997 Nov;10 (11) :1106-12. PMID: 9388061

Schofield K, D'Aquila T and Rimm DL: The cell adhesion molecule, E-cadherin, distinguishes mesothelial cells from carcinoma cells in fluids. Cancer. 1997 Oct 25;81 (5) :293-8. PMID: 9349517

Koslov ER, Maupin P, Pradhan D, Morrow JS and Rimm DL: Alpha-catenin can form asymmetric homodimeric complexes and/or heterodimeric complexes with beta-catenin. J Biol Chem. 1997 Oct 24;272 (43) :27301-6. PMID: 9341178

Ji X, Woodard AS, Rimm DL and Fearon ER: Transcriptional defects underlie loss of E-cadherin expression in breast cancer. Cell Growth Differ. 1997 Jul;8 (7) :773-8. PMID: 9218871

Ghoussoub RA and Rimm DL: Degree of dysplasia following diagnosis of atypical squamous cells of undetermined significance is influenced by patient history and type of follow-up. Diagn Cytopathol. 1997 Jul;17 (1) :14-9. PMID: 9218897

Rimm DL, Stastny JF, Rimm EB, Ayer S and Frable WJ: Comparison of the costs of fine-needle aspiration and open surgical biopsy as methods for obtaining a pathologic diagnosis. Cancer. 1997 Feb 25;81 (1) :51-6. PMID: 9100542

Williams ML, Rimm DL, Pedigo MA and Frable WJ: Atypical squamous cells of undetermined significance: correlative histologic and follow-up studies from an academic medical center. Diagn Cytopathol. 1997 Jan;16 (1) :1-7. PMID: 9034728

Cepek KL, Rimm DL and Brenner MB: Expression of a candidate cadherin in T lymphocytes. Proc Natl Acad Sci U S A. 1996 Jun 25;93 (13) :6567-71. PMID: 8692857

Rimm DL, Gmitro S and Frable WJ: Atypical reparative change on cervical/vaginal smears may be associated with dysplasia. Diagn Cytopathol. 1996 Jun;14 (4) :374-9. PMID: 8725141

Rimm DL, Koslov ER, Kebriaei P, Cianci CD and Morrow JS: Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc Natl Acad Sci U S A. 1995 Sep 12;92 (19) :8813-7. PMID: 7568023

Brady-Kalnay SM, Rimm DL and Tonks NK: Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo. J Cell Biol. 1995 Aug;130 (4) :977-86. PMID: 7642713

Rimm DL, Sinard JH and Morrow JS: Reduced alpha-catenin and E-cadherin expression in breast cancer. Lab Invest. 1995 May;72 (5) :506-12. PMID: 7745946

Rimm DL, Holland TE, Morrow JS and Anderson JM: Autoantibodies specific for villin found in patients with colon cancer and other colitides. Dig Dis Sci. 1995 Feb;40 (2) :389-95. PMID: 7851204

Cepek KL, Shaw SK, Parker CM, Russell GJ, Morrow JS, Rimm DL and Brenner MB: Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin. Nature. 1994 Nov 10;372 (6502) :190-3. PMID: 7969453

Rimm DL, Kebriaei P and Morrow JS: Molecular cloning reveals alternative splice forms of human alpha(E)-catenin. Biochem Biophys Res Commun. 1994 Sep 30;203 (3) :1691-9. PMID: 7945318

Rimm DL and Morrow JS: Molecular cloning of human E-cadherin suggests a novel subdivision of the cadherin superfamily. Biochem Biophys Res Commun. 1994 May 16;200 (3) :1754-61. PMID: 8185635

Rimm DL, Horness D, Kucera J and Blattner FR: Construction of coliphage lambda charon vectors with BamH1 cloning sites. 1980. Biotechnology. 1992;24 :220-8. PMID: 1422018

Thadani VM, Rimm DL, Urquhart L, Fisher L, Williamson PD, Enriquez R, Kim JH and Levy LL: 'Locked-in syndrome' for 27 years following a viral illness: clinical and pathologic findings. Neurology. 1991 Apr;41 (4) :498-500. PMID: 2011245

Pollard TD and Rimm DL: Analysis of cDNA clones for Acanthamoeba profilin-I and profilin-II shows end to end homology with vertebrate profilins and a small family of profilin genes. Cell Motil Cytoskeleton. 1991;20 (2) :169-77. PMID: 1751969

Rimm DL and Pollard TD: Purification and characterization of an Acanthamoeba nuclear actin-binding protein. J Cell Biol. 1989 Aug;109 (2) :585-91. PMID: 2760108

Morris RD, Rimm DL, Hartz AJ, Kalkhoff RK and Rimm AA: Obesity and heredity in the etiology of non-insulin-dependent diabetes mellitus in 32,662 adult white women. Am J Epidemiol. 1989 Jul;130 (1) :112-21. PMID: 2787103

Rimm DL, Sinard JH and Pollard TD: Location of the head-tail junction of myosin. J Cell Biol. 1989 May;108 (5) :1783-9. PMID: 2715178

Rimm DL and Pollard TD: New plasmid vectors for high level synthesis of eukaryotic fusion proteins in Escherichia coli. Gene. 1989 Feb 20;75 (2) :323-7. PMID: 2653968

Pollard TD, Tseng PC, Rimm DL, Bichell DP, Williams RC Jr, Sinard J and Sato M: Characterization of alpha-actinin from Acanthamoeba. Cell Motil Cytoskeleton. 1986;6 (6) :649-61. PMID: 2948678

Rimm DL, Horness D, Kucera J and Blattner FR: Construction of coliphage lambda Charon vectors with BamHI cloning sites. Gene. 1980 Dec;12 (3-4) :301-9. PMID: 6265323