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Specialized Translational Services

The Specialized Translational Services Lab provides automated quantitation along with in-situ analysis of proteins and nucleic acids.

STS miscroscope

Mission

Our mission is to provide standardized and reproducible high quality analyses of biomarker expression levels.

The specialized Translational Services Laboratory (STS Lab) at Yale University is a CLIA certified research and service facility.  We specialize in in-situ quantification of biomarkers in various tissue types, maintaining tissue morphology and spatial information.  We offer objective and reproducible quantification of proteins and nucleic acids of formalin fixed paraffin embedded (FFPE) tissues using quantitative immunofluorescence (QIF) to measure biomarkers of interest in tumor/stromal areas and subcellular compartments.  

       

Rimm, David L

Director Yale Pathology Tissue Services

Professor of Pathology and of Medicine (Medical Oncology)
Director of Pathology Tissue Services
Director of Translational Pathology

Research Interests: Quantitative Pathology; Cancer Tissue Biomarkers; Melanoma; Breast Cancer; Cell-cell adhesion in cancer; Translation of molecular techniques to diagnostic cytopathology; General Cytopathology; Immunohistochemistry; thyroid pathology

Clinical Interests: Molecular diagnostics; thyroid cytopathology; urine cytopathology; breast cancer; cancer biomarkers; growth factor receptors

       

Neumeister, Veronique

Director Specialized Translational Services Lab

Associate Research Scientist in Pathology

Research Interests: early breast carcinogenesis, development of companion diagnostic tests, in situ quantification of proteins and nucleic acids, development of prognostic and predictive biomarker signatures for breast and other cancers

       

McGuire, John

Research Assistant

Research Interests: Quantification of proteins, development of prognostic and predictive biomarker assays, immunohistochemistry,