GYN Translational Research Interests

Our team has a broad academic interest in the pathogenesis, diagnosis, therapeutic markers of neoplastic and pre-neoplastic lesions of gynecological organs - ovary, uterus, cervix, vulva and vagina. With available state-of-the-art molecular and genetic technology, we are currently undertaking focused investigations of the disease entities including gestational trophoblastic disease, endometrial cancers, uterine smooth muscle neoplasms and cervical glandular lesions. These research endeavors involve highly committed faculty and enthusiastic pathology trainees. A major effort in the gestational trophoblastic disease research program is to improve diagnostic accuracy by incorporating ancillary techniques including DNA genotyping and immunohistochemistry. Studies of endometrial cancers are aimed at identifying (1) early precursor lesions and (2) diagnostic, prognostic and predictive biomarkers. Many of the projects are designed and tailored to the long-term academic career development of individual members and frequently in close collaboration with the Yale Gynecologic Oncology group.


Bio Profile

Pei Hui, PhD, MD

Director GYN Pathology

Professor of Pathology

Clinical Director, Molecular Diagnostics Laboratory

Director, Gynecologic Pathology

Director, Gynecologic and Breast Pathology Fellowship Program.

Research Interests

Breast Neoplasms; Gynecology; Ovarian Neoplasms; Pathology; Endometrial Neoplasms; Molecular Diagnostic Techniques; Gestational Trophoblastic Disease; Genotyping Techniques

I am an academic surgical and molecular pathologist serving Yale-New Haven Hospital and the greater New Haven area with (1) clinical responsibilities including diagnostic gynecologic pathology and molecular diagnostic services, (2) resident training and medical student teaching, and (3) translational and clinical research programs in the fields of gynecologic pathology and molecular diagnostics.

View Full Profile

Bio Profile

Natalia Buza, MD

Assistant Professor of Pathology

Associate Director of Gynecologic Pathology

Research Interests

Breast Diseases; Uterine Cervical Neoplasms; Ovarian Neoplasms; Uterine Neoplasms; Vulvar Neoplasms; Pathological Conditions, Anatomical; Morphological and Microscopic Findings

Dr. Buza specializes in breast and gynecological pathology. She has been part of the Yale Pathology Breast and GYN team since 2010.

View Full Profile

Bio Profile

Susan V Fernandez

Assistant Professor of Pathology

Assistant Professor

View Full Profile

Bio Profile

Serena Wong, MD

Assistant Professor of Pathology

View Full Profile

Additional Team Members

Pathology residents currently pursuing research projects within gynecologic pathology:

Agedi BotoJoshua JeantyRita Abi-Raad, Ryan Carr, and Ahmed Alomari

Collaboration with the members of the Yale Gynecologic Oncology group, lead by Dr. Thomas Rutherford.