Natalia Buza, MD

Associate Professor of Pathology; Associate Director of Gynecologic Pathology

Physician Biography

As a pathologist specializing in gynecologic and breast cancers and diseases, Natalia Buza, MD, rarely sees the patients she spends many hours thinking about; her work is done not in an exam room, but behind a high-powered microscope. This doesn’t make her patients any less real, however. Dr. Buza explains that she became a pathologist because “it’s an exciting discipline and so important for patient care.” 

Working closely with gynecologic cancer doctors, Dr. Buza examines samples of patients’ tissue taken for a biopsy to look for signs of endometrial, ovarian and cervical cancers. Once a cancer has been identified, she continues her examination of the cells, specifying the tumor subtype and looking for specific markers at the protein and genetic level that could help the patient’s physician create a personalized cancer treatment plan. Also, she notes, “I do a lot of collaborative research and studies.” For example, she and other colleagues recently investigated the possibility of using targeted anti-HER2 therapy in certain endometrial cancers. 

Dr. Buza is an associate professor of pathology and associate director of gynecologic pathology at Yale School of Medicine.

Clinical Interests

  • Uterine Cervical Diseases
  • Uterine Cervical Dysplasia
  • Uterine Cervical Neoplasms
  • Endometrial Hyperplasia
  • Endometriosis
  • Endometritis
  • Ovarian Cysts
  • Ovarian Diseases
  • Ovarian Neoplasms
  • Ovary
  • Pathology Department, Hospital
  • Pathology, Surgical
  • Vaginal Diseases
  • Vulvar Neoplasms
  • Endometrial Neoplasms
  • Sarcoma, Endometrial Stromal
  • Carcinoma, Endometrioid
  • Cervical Intraepithelial Neoplasia
  • Gestational Trophoblastic Disease
  • Choriocarcinoma, Non-gestational
  • Endometrial Stromal Tumors
  • Hereditary Breast and Ovarian Cancer Syndrome

Patient Care

Accepts new patients? Yes
Patient Type: Adult; Adolescent; Geriatric
Referrals: MD to MD Consult

Patient Care Organizations

Pathology: Surgical Pathology: Breast Pathology; Gynecological Pathology

Yale Cancer Center: Breast Center

Yale Medicine

Office of Cooperative Research

Board Certifications

  • Anatomic Pathology AB of Pathology (2009)

Clinical Trials

Conditions Study Title
Corpus Uteri A phase II evaluation of pembrolizumab, a fully human antibody against PD-1, in the treatment of persistent or recurrent hypermutated/ultramutated endometrial cancer identified by next generation sequencing (NGS) and comprehensive genomic profiling (CGP), A Pilot Study
Cervix Uteri Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) Using a Novel "Prime and Pull" Strategy

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Contact Info

Natalia Buza, MD
Patient Care Locations
Yale PathologyYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Farnam Memorial Building
310 Cedar Street

New Haven, CT 06510
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Office Location
Yale Pathology - EPYale New Haven Hospital
20 York Street, Ste EP2-608B

New Haven, CT 06510
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Mailing Address
310 Cedar Street
PO Box 208023

New Haven, CT 06520-8023